Retisphere Gel

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 22 Feb 2026 | 06:32 PM (IST)

Retisphere Gel is a prescription medicine that has a combination of medicines that are used to treat acne. It removes the dead layer of the skin, which is present on the top, and stops the growth of bacteria.

Genuine

Authenticity Assured

Prescription

required

₹231 MRP ₹253.139% off

Retisphere Gel is currently sold out

Same composition alternative:

Deriva-Bpo Gel

₹518~~₹561~~

Available alternative from Glenmark Pharmaceuticals

Sold out

Retisphere Gel

tube of 25 gm Gel

₹231

~~₹253.13~~

Same composition

Deriva-Bpo Gel

tube of 20 gm Gel

Adapalene (0.1% w/w) + Benzoyl Peroxide (2.5% w/w)

by Glenmark Pharmaceuticals Ltd

Get in 30 mins

₹518

₹22.0 per gm

₹440

order for

₹1200

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Adapalene (0.1% w/w)+ Benzoyl Peroxide (2.5% w/w)

Marketer

Amwill Healthcare

Storage

Store below 30°C

The content is shown in English

Product introduction

Retisphere Gel should be used in the dose and duration as advised by your doctor. It is for external use only. Wash your hands before using this medicine. Apply only on the affected areas of the skin. It is advised to check the label for directions before use.

The most common side effects include skin irritation, itchiness, burning, and sensation at the application site. If this side effect persists for a longer duration, inform your doctor. In case by accident, this medicine goes into your eyes, ears, nose, or mouth, immediately rinse it with water.

Inform your doctor if you notice darkening discoloration or a severe burning sensation on the treated skin. Inform your doctor if you have known allergies to this medicine. If you are pregnant or breastfeeding and suffering from any other condition, please inform your doctor.

Uses of Retisphere Gel

Acne

Benefits of Retisphere Gel

Acne
Retisphere Gel helps treat acne by reducing the production of excessive oil in the skin. This helps keep your pores open and prevent further acne breakouts. It helps reduce redness and swelling around acne and promotes healing. It also helps reduce acne blemishes and gives you a smoother-looking skin. Retisphere Gel usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. This medicine will help improve your mood and uplift your confidence as acne reduces.

Side effects of Retisphere Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Retisphere

Burning sensation

How to use Retisphere Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Retisphere Gel works

Retisphere Gel is a combination of two medicines: Adapalene and Benzoyl Peroxide, which treat acne (pimples). Adapalene is a form of vitamin A, and Benzoyl Peroxide is a keratolytic medicine. Together, they prevent the accumulation of sebum (skin’s natural oil), unblock the pores, and allow natural exfoliation of the outer layers of the skin. Benzoyl Peroxide additionally penetrates the skin and kills acne-causing bacteria.

All substitutes for Retisphere Gel

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Apply it to the affected area once a day at bedtime.
Retisphere Gel can make your skin more sensitive to sunlight. Apply sunscreen or wear protective clothing while stepping out.
Avoid getting it in your eyes or mouth. If this happens, rinse with water immediately.
Do not apply to broken, sunburnt, or sensitive areas of skin. Inform your doctor if you notice unusual dryness, redness, and peeling of the skin.
Be careful when applying Retisphere Gel to large areas since it can bleach hair, clothing, and furnishings upon contact.
Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Safety advice

Alcohol

No interaction found/established

Pregnancy

UNSAFE

Retisphere Gel is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

SAFE IF PRESCRIBED

Retisphere Gel may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

What are the instructions for the storage and disposal of Retisphere Gel?

Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

Can I use Retisphere Gel as a spot treatment (single pimple)?

It is not used for spot treatment and should not be used to treat a single pimple. Retisphere Gel should be applied to the entire face. Using it once daily can help treat your acne.

How long does Retisphere Gel take to work?

It may take up to 2-3 weeks before your symptoms improve. Retisphere Gel may take some time to deliver significant results. Use the medicine as directed and tell your doctor if your symptoms do not improve or if they get worse.

Fact Box

Habit Forming

Therapeutic Class

DERMA

References

User feedback

Patients taking Retisphere Gel

Once A Day

85%

Four Times A Day

Twice A Day

What are you using Retisphere Gel for?

Acne

100%

How much was the improvement?

Average

67%

Excellent

20%

Poor

13%

What were the side-effects while using Retisphere Gel?

No Side Effect

50%

Skin irritation

17%

Skin peeling

17%

Dry skin

17%

How do you take Retisphere Gel?

With or without food

33%

Empty stomach

33%

With food

33%

Please rate Retisphere Gel on price

Not Expensive

47%

Average

33%

Expensive

20%

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Amwill Healthcare
Address: No.157, 1st Floor, 2nd Main Road, 3rd Cross, Chamrajpet, Bangalore, Karnataka 560018 – India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Retisphere Gel

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Retisphere Gel

Benefits of Retisphere Gel

Side effects of Retisphere Gel

How to use Retisphere Gel

How Retisphere Gel works

All substitutes for Retisphere Gel

Minoz-BPO Gel

Peroduo Gel

Persol PLUS Gel

Epiduo 0.1%/2.5% Gel

aDApero Gel

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What are the instructions for the storage and disposal of Retisphere Gel?

Can I use Retisphere Gel as a spot treatment (single pimple)?

How long does Retisphere Gel take to work?

Fact Box

Habit Forming

Therapeutic Class

References

User feedback

Patients taking Retisphere Gel

What are you using Retisphere Gel for?

How much was the improvement?

What were the side-effects while using Retisphere Gel?

How do you take Retisphere Gel?

Please rate Retisphere Gel on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests