RB FLEX 20MG/1ML INJECTION

Pentoxifylline (20mg/1ml)

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RB FLEX 20MG/1ML INJECTION is used to treat peripheral vascular disease (poor circulation to the arms and legs) and intermittent claudication (pain on walking or at rest caused by poor circulation to the legs). It works by increasing the blood flow to the arms and legs.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 29 Apr 2026 | 11:11 AM (IST)

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General Information

Contains

Pentoxifylline (20mg/1ml)

Marketer

Torrent Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

RB FLEX 20MG/1ML INJECTION is administered under the supervision of a doctor. Your doctor will decide the dose and duration of the medicine for you. You should continue all your other medicines that are advised by the doctor for your long-term treatment even after this injection.

Common side effects of this medicine include nausea, vomiting, diarrhea, dizziness, headache, flushing (sense of warmth in the face, ears, neck, and trunk), and weakness. Consult your doctor if these effects bother you. This medicine is used with caution for some people. Thus, you must inform the doctor if you are suffering from any liver or kidney disease. Also, let your doctor know if you are pregnant or breastfeeding and about all the other medications that you are taking regularly.

Uses of RB Flex Injection

Peripheral vascular disease
Intermittent claudication

Benefits of RB Flex Injection

Peripheral vascular disease
Peripheral vascular disease refers to the condition of disturbed blood circulation in blood vessels. RB FLEX 20MG/1ML INJECTION prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). It helps prevent the formation of blood clots and also prevents the existing ones from growing bigger in size. Make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.

Intermittent claudication
Intermittent claudication refers to muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), classically in the calf muscle, which occurs during exercise or even walking, and it gets better with a short period of rest. RB FLEX 20MG/1ML INJECTION helps relieve this pain in the legs that is caused due to disturbed blood supply in the legs. It helps prevent formation of blood clots, improves blood flow and maintains free flowing of blood in your body.

Side effects of RB Flex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of RB Flex

Bloating
Diarrhea
Flushing (sense of warmth in the face, ears, neck and trunk)
Heartburn
Lightheadedness
Nausea
Stomach discomfort
Vomiting
Weakness
Headache
Dizziness

How to use RB Flex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How RB Flex Injection works

RB FLEX 20MG/1ML INJECTION is a peripheral vasodilator. It works by decreasing the thickness (viscosity) of blood, allowing it to pass more easily through the blood vessels. This effect is beneficial in peripheral vascular disease, where the blood vessels in the arms and legs are narrowed.

Quick tips

Do not drive or perform activities that require mental focus until you know how RB FLEX 20MG/1ML INJECTION affects you.
Your doctor may get regular blood tests done to monitor liver function while taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with RB FLEX 20MG/1ML INJECTION. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

RB FLEX 20MG/1ML INJECTION is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

RB FLEX 20MG/1ML INJECTION may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

RB FLEX 20MG/1ML INJECTION may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

RB FLEX 20MG/1ML INJECTION should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

RB FLEX 20MG/1ML INJECTION should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking RB Flex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Aminophylline (Oral Route)

Do not consume Aminophylline with Pentoxifylline. If concurrent use is essential, watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may monitor and adjust the dose of Aminophylline accordingly. Pentoxifylline may raise blood levels of Aminophylline.

Severe

Phenindione (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Severe

Ciprofloxacin (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Ciprofloxacin may raise blood levels of Pentoxifylline.

Severe

Ciprofloxacin (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Ciprofloxacin may raise blood levels of Pentoxifylline.

Severe

Aminophylline (Injection Route)

Fact Box

Chemical Class

Xanthine derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Hemorrheologic Agents

References

Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 205.
Gersh BJ, Opie LH. Which Therapy for Which Condition? In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1089-90.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pentoxifylline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Pentoxifylline [Prescribing Information]. Bridgewater, NJ: Sanofi-Aventis US, LLC.; 2010. [Accessed 27 Jul. 2024] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India

Lab tests offered by us

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RB FLEX 20MG/1ML INJECTION

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General Information

Contains

Marketer

Storage

Product introduction

Uses of RB Flex Injection

Benefits of RB Flex Injection

Side effects of RB Flex Injection

How to use RB Flex Injection

How RB Flex Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Phenindione (Oral Route)

Ciprofloxacin (Oral Route)

Ciprofloxacin (Injection Route)

Aminophylline (Injection Route)

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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