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Pentoxifylline

INFORMATION

Uses

Pentoxifylline is used in the treatment of peripheral vascular disease (poor circulation to the arms and legs) and intermittent claudication (pain on walking or at rest caused by poor circulation to the legs).

How it works

Pentoxifylline reduces the action of a protein called phosphodiesterase making erythrocyte membrane more resistant to deformity. It also decreases blood viscosity and promotes proper blood flow thereby relieving pain.

Common side effects

Nausea, Abdominal bloating, Agitation, Aseptic meningitis, Biliary obstruction, Bleeding, Blood in vomit, Blood in stool, Diarrhoea, Dizziness, Headache, Altered heart rate, Skin bleeding, Skin redness, Tachycardia, Vomiting

AVAILABLE MEDICINE

Expert advice

  • Do not use pentoxifylline if you are allergic (hypersensitive) to pentoxifylline or any other ingredient in the medicine.
  • Do not use pentoxifylline if you have serious heart problems, if you had a stroke with bleeding in brain; or if you had bleeding in the eye.
  • Patients taking pentoxifylline are advised to exercise caution while driving or operating machines.
  • Do not stand up and raise from the bed quickly as it may cause dizziness.

Frequently asked questions

Pentoxifylline

Q.Is pentoxifylline a blood thinner/ an anticoagulant/ a narcotic/ an antibiotic?
Pentoxifylline is not an anticoagulant or an antibiotic or a narcotic. Pentoxifylline is vasodilator (dilates blood vessels) and improves blood flow

Q.Is pentoxifylline safe?
Pentoxifylline is safe at prescribed dose and duration as advised by your doctor

Q.Is pentoxifylline over the counter?
No. Pentoxifylline belongs to the schedule H and can be obtained only on production of valid prescription

Q.Does pentoxifylline work for Peyronie's disease?
Yes, pentoxifylline can be used for Peyronie's disease

Q.How does pentoxifylline work in alcoholic hepatitis?
Pentoxifylline may improve short-term survival in chronic alcoholic hepatitis

Q.Does pentoxifylline cause weight gain?
Pentoxifylline may cause weight gain but this is very rare side effect.


Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)