Raparen 1 mg Tablet


Overview

Uses of Raparen Tablet

Raparen 1 mg Tablet is used for prevention of kidney transplant rejection.

Raparen Tablet side effects

Common
  • Increased risk of infection
  • Mouth ulcer
  • Vomiting
  • Nausea
  • Decreased blood cells (red cells, white cells, and platelets)
  • Stomach upset
  • Protein in urine

How to use Raparen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Raparen 1 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Raparen Tablet works

Raparen 1 mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

Raparen Tablet related warnings

Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Raparen 1 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Raparen 1 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
SAFE
Raparen 1 mg Tablet does not usually affect your ability to drive.
Kidney
SAFE
Raparen 1 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Raparen 1 mg Tablet is recommended.
Liver
Raparen 1 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Raparen 1 mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Raparen 1 mg Tablet
₹157.4/Tablet
Siromus 1mg Tablet
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Expert Advice

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.

Interaction with Drugs

Taking Raparen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Clarimac
LIFE-THREATENING
Brand(s): Zuroxy, Roxilim, Rox Thro
LIFE-THREATENING
Brand(s): Torcillin
SERIOUS
Brand(s): Indizole, Itraspan, Itzo
SERIOUS
Brand(s): Shinosun
SERIOUS
Brand(s): Ketozoe, Ketazol
SERIOUS
Brand(s): Fungis, Fluzole
SERIOUS
Brand(s): Benzol
SERIOUS
Brand(s): Stoin
SERIOUS

User Feedback


FAQs

Q. Is Raparen dialyzable?

Raparen is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.

Q. Is Raparen a calcineurin inhibitor?

Raparen is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system

Q. Is Raparen cytotoxic?

Raparen is a cytotoxic agent

Q. What is Raparen-eluting stent?

The Raparen-eluting stent is a metal stent coated with 140 µg/cm2 of Raparen blended with synthetic polymers. After stent implantation, Raparen is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month

Q. Does Raparen cause hair loss?

Raparen causes hair loss

Q. Why does Raparen cause hyperlipidemia?

Raparen alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
Information last updated by Dr. Varun Gupta, MD Pharmacology on 6th Sep 2018.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
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MRP
1574
10 tablets in 1 strip
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