Puregraf 150 IU PFS
Prescription Required
Product introduction
Puregraf 150 IU PFS is used in the treatment of infertility in women. It is also helpful in the treatment of male hypogonadism (delayed puberty, and low sperm count) and male infertility. It works by releasing the eggs from the ovary in women and by increasing the testosterone level in men.
Puregraf 150 IU PFS is given as an injection under the supervision of a doctor. Your doctor will decide the right time to take the injection, so always follow your doctor's advice. The dose and how often you take it depends on what you are taking it for. You might be prescribed with certain other medicine as a part of your treatment. You should take this medicine for as long as it is prescribed for you.
The most common side effects of this medicine include headache, injection site pain, injection site allergic reaction, abdominal swelling, or pain. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Male might notice acne, or sweating and deepening of the voice.
Before taking this medicine, tell your doctor if you have ever had heart disease, or had an ovarian cyst, or had thyroid gland disorder. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. You should avoid alcohol or have to follow doctor advice related to diet while taking this medicine.
Uses of Puregraf Injection
- Female infertility
- Male hypogonadism
- Male infertility
Benefits of Puregraf Injection
In Female infertility
Puregraf 150 IU PFS helps in normal development of an egg in a woman's ovary (female reproductive organ), and stimulates the release of a healthy, matured egg. This helps to treat infertility in women and increases the chance of a successful pregnancy. It is given as an injection by a doctor or nurse and should not be self-administered. You should use the medicine as prescribed for it to be effective.
In Male hypogonadism
Male Hypogonadism is the improper functioning of reproductive organs, that is, testes in males, which causes failure to produce sex hormones required for fertility. Puregraf 150 IU PFS acts as the male sex hormone, testosterone and therefore, improves sperm production in males. This can reduce infertility and helps to treat hypogonadism in males. Follow your doctor’s instructions carefully to get the most benefit.
In Male infertility
Male infertility refers to a male's inability to cause pregnancy in a fertile female. This may be due to inadequate amount of sex hormone in males which affects the sperm health as well as sperm count. Puregraf 150 IU PFS behaves as the male sex hormone, testostrone, and helps in treating infertility in males. It improves sperm count as well as their quality. This helps proper functioing of sex organs in males and increase schances of conceiving for a female.
Side effects of Puregraf Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Puregraf
- Headache
- Injection site pain
- Injection site allergic reaction
- Abdominal pain
- Abdominal cramp
- Nausea
How to use Puregraf Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Puregraf Injection works
Puregraf 150 IU PFS is a mixture of hormones. In females, it works by facilitating the maturation of follicles (which contain eggs) in the ovaries. This helps treat female infertility due to improper egg production (anovulatory infertility). In males, it works by increasing the low sperm count.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with Puregraf 150 IU PFS. Please consult your doctor.
Pregnancy
UNSAFE
Puregraf 150 IU PFS is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Puregraf 150 IU PFS during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether Puregraf 150 IU PFS alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Puregraf 150 IU PFS in patients with kidney disease. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Puregraf 150 IU PFS in patients with liver disease. Please consult your doctor.
What if you forget to take Puregraf Injection?
If you miss a dose of Puregraf 150 IU PFS, please consult your doctor.
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For informational purposes only. Consult a doctor before taking any medicines.
Puregraf 150 IU PFS
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Quick tips
- Puregraf 150 IU PFS stimulates the production of eggs in women undergoing treatment for infertility.
- It may also be used to stimulate sperm formation in men.
- Your doctor may prescribe more than one medicine as part of your suggested pregnancy plan.
- Pregnancy following treatment with Puregraf 150 IU PFS is more likely to result in a multiple pregnancy (twins or more) than if you had conceived naturally.
- The injection is administered under the skin. Follow the recommended dosage and monitoring schedules to minimise the possibility of ovarian hyperstimulation.
- Inform your doctor immediately if you have severe pelvic pain, nausea, vomiting, diarrhea, sudden weight gain, trouble breathing, or decreased or no urination during treatment, as these could be symptoms of ovarian hyperstimulation syndrome (OHSS).
- Do not use Puregraf 150 IU PFS if you are already pregnant or breastfeeding.
Fact Box
Chemical Class
Hormones
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Action Class
Gonadotropins
Patient concerns
FAQs
What is Puregraf 150 IU PFS and what it is used for?
Puregraf 150 IU PFS contains an active ingredient called Menotrophin. Menotrophin is a mixture of follicle stimulating hormone (FSH) and luteinizing hormone (LH). It is used to treat infertility in women, who face a problem with ovulation. It works by helping follicles (which contains egg) to mature in the ovaries, resulting in the release of a properly developed egg. It is also used in assisted reproductive technology procedures (ART) such as in-vitro fertilization (IVF), which help women to become pregnant. It may also be used in adult men, who have low sperm cell count, due to lack of certain hormones.
How and in what dose can it be used?
It is given as an injection into a muscle or under the skin. Always take this medicine as prescribed by your doctor. Your doctor might decide the dose based on your gender and the condition for which treatment is being given. In women, treatment duration depends on the ovarian response, for which constant monitoring is done by the doctor.
What if I miss a dose of Puregraf 150 IU PFS?
Ideally, you should try not to miss a dose of Puregraf 150 IU PFS. However, please talk to your doctor as soon as you remember that you have missed a dose.
What are the side effects of using Puregraf 150 IU PFS?
The common side effects are pain and swelling at injection site, headache, nausea, vomiting, and stomach pain. If any of these side effects bother you, please consult with your doctor. In addition, this medicine may increase the likelihood of conditions like ovarian hyperstimulation syndrome (OHSS) and multiple pregnancy.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Menotropins. Parsippany, New Jersey: Ferring Pharmaceuticals Inc.; 1975 [revised Feb. 2014]. [Accessed 24 Jan. 2019] (online) Available from:
- Menotrophin. Church Road, West Drayton: Ferring Pharmaceuticals Ltd.; 2010 [revised Jun. 2011]. [Accessed 03 Apr. 2019] (online) Available from:
- Menotropins [Prescribing Information]. Parsippany, NJ: Ferring Pharmaceuticals; 2014. [Accessed 25 Jul. 2024] (online) Available from:
Marketer details
Name: Gufic Bioscience Ltd
Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)
Country of origin: India
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1.0 Injection in 1 prefilled syringe
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