Prulac Syrup

Lactulose (10gm/15ml)

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Prulac Syrup is a type of sugar used to treat constipation. It is a laxative that makes your stool easier to pass by drawing water into your bowel. It is also used to treat hepatic encephalopathy (a liver disease causing confusion, tremor, and decreased level of consciousness).

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 07 May 2026 | 03:31 PM (IST)

MRP ₹196.88

Gurgaon

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Prulac Syrup

bottle of 200 ml Oral Solution

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General Information

Contains

Lactulose (10gm/15ml)

Marketer

Pmed Healthcare

Storage

Store below 25°C

The content is shown in English

Product introduction

Prulac Syrup can be taken with or without food. Take it in the exact dose and duration advised by your doctor. Use it regularly to get the maximum benefit. Your doctor may adjust the dose depending on how well it is working. Do not take more than or longer than the advised duration. This medicine takes at least 48 hours to work. Talk to your doctor if you are still constipated after 3 days. The most common side effects are diarrhea, flatulence, nausea, vomiting, and abdominal pain. These are usually mild and go away after a couple of days. Occasionally, people develop serious side effects, including severe diarrhea and electrolyte imbalance. Talk to your doctor straight away if you notice any of these. Before taking this medicine, tell your doctor if you have diabetes or if you are unable to digest milk sugar (lactose intolerant). If you are taking this medicine for the long term, your doctor may recommend occasional blood tests to check your mineral levels (e.g., potassium and sodium). Do not take other laxative alone with this medicine, and check with your doctor if you are pregnant or breastfeeding.

Uses of Prulac Oral Solution

Constipation : Prulac Syrup helps soften hard and dry stools and make them easier to pass.
Treatment of Hepatic encephalopathy

Benefits of Prulac Oral Solution

Constipation
Constipation occurs when bowel movements become less frequent, and stools are hard to pass. Prulac Syrup helps soften the stool and increases bowel movement frequency by drawing water into the intestines. This provides gentle and effective relief from constipation and improves digestive comfort.

Treatment of Hepatic encephalopathy
Hepatic encephalopathy is a liver-related condition that affects brain function due to the buildup of toxins in the blood. Prulac Syrup helps remove these toxins, especially ammonia, through bowel movements. This helps improve mental clarity, reduces confusion, and supports better liver health and overall well-being.

Side effects of Prulac Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prulac

Nausea
Flatulence
Abdominal pain
Diarrhea
Vomiting

How to use Prulac Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Prulac Syrup may be taken with or without food.

How Prulac Oral Solution works

Prulac Syrup works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

All substitutes for Prulac Syrup

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Prulac Syrup should preferably be taken at bedtime, as it requires 6 to 8 hours to show its effect.
It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by your doctor.
Inform your doctor if you have a history of stomach disorders such as appendicitis or a bowel obstruction.
Eat a fiber-rich diet (20–35 g/day) and drink 8–10 glasses of water daily to keep stools soft and regular.
Exercise regularly (at least 3 times a week) to support healthy bowel movements.
Do not delay bowel movements, as holding stool can worsen constipation.
Do not take this medicine for several months unless specifically advised by your doctor, especially for chronic conditions.
If you are using this medicine for a liver-related condition, your doctor may ask you to monitor and record the number of bowel movements per day.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Prulac Syrup. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Prulac Syrup is safe to use during pregnancy. Most studies have shown low or no risk to the developing baby.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

SAFE

Prulac Syrup does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Prulac Syrup in patients with kidney disease. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Prulac Syrup is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Prulac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Acenocoumarol (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine). Lactulose may increase the effect of Acenocoumarol.

Moderate

Warfarin (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine). Lactulose may increase the effect of Warfarin.

Mild

Mesalazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Lactulose may reduce blood levels and efficacy of the active form of Mesalazine.

Frequently asked questions

How should Prulac Syrup be taken?

Take Prulac Syrup exactly as advised by your doctor. It is usually taken by mouth, with or without food. You may take it with water or fruit juice to improve the taste. Try to take it at the same time each day to help maintain a regular bowel routine. Follow the prescribed dose and do not change it without consulting your doctor.

How long does it take for Prulac Syrup to work?

Prulac Syrup may take about 24 to 48 hours to produce a bowel movement. It does not work immediately. In some people, it may take a little longer. Continue taking it as advised and speak to your doctor if you do not notice any improvement after a few days.

Is it okay to take Prulac Syrup every day?

Prulac Syrup may be prescribed for daily use in certain conditions. However, it should only be taken for the duration recommended by your doctor. Long-term or frequent use without medical supervision is not advised. Always follow your doctor’s instructions regarding how long to continue treatment.

Can I take other laxatives along with Prulac Syrup?

You should not take other laxatives along with Prulac Syrup unless your doctor advises it. Using multiple laxatives at the same time may increase the risk of diarrhea, dehydration, or electrolyte imbalance. If constipation persists, consult your doctor before adding any other medicine.

What if I take more than the recommended dose of Prulac Syrup?

Taking more than the recommended dose of Prulac Syrup may cause diarrhea, stomach cramps, or dehydration. In some cases, it may also disturb your body’s electrolyte balance. If you have taken too much and feel unwell, contact your doctor for advice. Drink enough fluids if diarrhea occurs.

What is Prulac Syrup and what is it used for?

Prulac Syrup is a laxative. It is commonly used to treat constipation by helping soften the stool and making it easier to pass. In some cases, it may also be prescribed for certain liver-related conditions where reducing blood ammonia levels is required. Your doctor will decide the appropriate use based on your condition.

Is it safe to use Prulac Syrup if I have diabetes?

Prulac Syrup contains small amounts of sugars such as lactose and galactose. These sugars are absorbed in small amounts, but they may affect blood glucose levels if taken in high doses or for a long time. If you have diabetes, inform your doctor before starting this medicine. Your blood sugar may need to be monitored during treatment.

Does Prulac Syrup cause gas or abdominal bloating?

Gas, bloating, and mild stomach cramps are common, especially during the first few days of treatment. These effects occur because gut bacteria break down the sugars in the medicine, which can produce gas. These symptoms often improve with continued use. Consult your doctor if the discomfort becomes severe or persistent.

Is Prulac Syrup safe for patients with lactose intolerance?

Prulac Syrup contains small amounts of lactose. People with lactose intolerance may experience gas, bloating, or stomach cramps after taking it. If you are sensitive to dairy products, inform your doctor before starting this medicine. They can decide whether this option is suitable for you.

Does Prulac Syrup help with acidity or gas?

No, Prulac Syrup is not an antacid. It is used to relieve constipation by promoting bowel movements. It may actually increase gas during the initial days of use. If you have symptoms such as heartburn or reflux, talk to your doctor about appropriate treatment options.

Fact Box

Chemical Class

O-glycosyl compounds

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Osmotic Laxatives / Purgatives

Related lab tests

Ammonia

Liver Function Test

Potassium

Sodium

References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1332.
McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1079.
Lactulose. Maidenhead, Berkshire: Intrapharm Laboratories Limited; 2015 [revised 12 Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
Lactulose. Greenville, SC: PAI Pharma; 2025 [Accessed 04 Feb. 2026] (online). Available from:
Lactulose. Olst, The Netherlands: Abbott Biologicals B.V.; 2022 [Accessed 04 Feb. 2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)IndoRama Health Care Pvt. Ltd.
Address: A)204-205, HSIIDC, Manakpur, Industrial Area Jagadhri, Distt. Yamuna Nagar (Haryana)-135003

Marketer details

Name: Pmed Healthcare
Address: Property No. 19, 2nd Floor, Shopping Centre, Lawrence Road, Industrial Area, Delhi-110035

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Prulac Syrup

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Prulac Oral Solution

Benefits of Prulac Oral Solution

Side effects of Prulac Oral Solution

How to use Prulac Oral Solution

How Prulac Oral Solution works

All substitutes for Prulac Syrup

Easylax L Oral Solution Lemon Sugar Free

Easylax L Oral Solution Lemon Sugar Free

Lactolook Oral Solution Sugar Free

Looz Oral Solution

Emty Oral Solution

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Acenocoumarol (Oral Route)

Warfarin (Oral Route)

Mesalazine (Oral Route)

Frequently asked questions

How should Prulac Syrup be taken?

How long does it take for Prulac Syrup to work?

Is it okay to take Prulac Syrup every day?

Can I take other laxatives along with Prulac Syrup?

What if I take more than the recommended dose of Prulac Syrup?

What is Prulac Syrup and what is it used for?

Is it safe to use Prulac Syrup if I have diabetes?

Does Prulac Syrup cause gas or abdominal bloating?

Is Prulac Syrup safe for patients with lactose intolerance?

Does Prulac Syrup help with acidity or gas?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Ammonia

Liver Function Test

Potassium

Sodium

References

Want to know more

Have issue with the content

Disclaimer

Manufacturer details

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests