Prucalax Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 21 Jan 2026 | 01:28 AM (IST)

Prucalax Tablet is a prescription medicine used in the treatment of constipation. It increases the release of certain chemicals that improve the movement of food inside the intestine and help to increase gastric emptying of both liquid and solid.

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General Information

Contains

Prucalopride (2mg)

Marketer

Kylon Remedies Pvt. Ltd.

Storage

Store below 25°C

The content is shown in English

Product introduction

Prucalax Tablet is taken with or without food in a dose and duration as advised by the doctor. The dose you're given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking, as some may affect, or be affected by, this medicine.

The most common side effects are headache, nausea, abdominal pain, decreased appetite, dizziness, and dyspepsia. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. This medicine may cause diarrhea, so it is better to take plenty of fluids while taking this medicine, as it may help to prevent dehydration.

Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. You should avoid this medicine if you are suffering from bleeding ulcers of the stomach. Consult with your doctor if you are pregnant or breastfeeding.

Uses of Prucalax Tablet

Treatment of Constipation

Benefits of Prucalax Tablet

Treatment of Constipation
Constipation refers to infrequent or difficult bowel movements that can lead to bloating, discomfort, and a feeling of incomplete evacuation. Prucalax Tablet helps relieve chronic constipation when laxatives have not worked by improving bowel motility and increasing complete bowel movements, which can reduce bloating and discomfort.

Side effects of Prucalax Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Prucalax

Decreased appetite
Dizziness
Indigestion
Diarrhea
Nausea
Abdominal pain
Headache
Dyspepsia
Abnormal gastrointestinal sound
Vomiting
Flatulence
Fatigue

How to use Prucalax Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Prucalax Tablet may be taken with or without food.

How Prucalax Tablet works

Prucalax Tablet is a selective 5-HT4 receptor agonist that has high intrinsic activity. It indirectly stimulates the release of acetylcholine, a chemical messenger that increases the motility of the intestine and treats even chronic (long-term) constipation very effectively.

All substitutes for Prucalax Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Prucalax Tablet helps treat chronic constipation and improve bowel movements, when laxatives have failed to provide adequate relief.
It can be taken with or without food, at any time of the day.
It may cause diarrhea. Drink plenty of water and inform your doctor if it bothers you.
Inform your doctor if your constipation has not improved even after four weeks of taking this medication.

Safety advice

Alcohol

SAFE

Consuming alcohol with Prucalax Tablet does not usually cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Prucalax Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Prucalax Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Prucalax Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Prucalax Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Prucalax Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
Limited information is available on the use of Prucalax Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.

Interaction with drugs

Taking Prucalax with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Erythromycin (Oral Route)

If concurrent use is essential, your doctor may monitor your electrocardiogram (ECG) regularly.

Moderate

Erythromycin (Injection Route)

If concurrent use is essential, your doctor may monitor your electrocardiogram (ECG) regularly.

Moderate

Atropine (Injection Route)

If concurrent use is essential, please consult with your doctor.

Mild

Ciclosporin (Injection Route)

Your doctor may monitor the treatment outcome and may modify the treatment protocol as per the observation.

Mild

Ciclosporin (Oral Route)

Your doctor may monitor the treatment outcome and may modify the treatment protocol as per the observation.

Frequently asked questions

How quickly does Prucalax Tablet work?

Prucalax Tablet has been found to act rapidly, but the effect varies from person to person. This is because the response to a particular medication varies in every patient.

Is Prucalax Tablet safe in pregnancy?

Prucalax Tablet is not recommended during pregnancy. Use during pregnancy should be avoided. It is important to consult your doctor before starting this medication. Additionally, women of childbearing potential should use effective contraception during treatment with this medicine.

When should I take Prucalax Tablet?

Prucalax Tablet can be taken at any time of the day. Normally, it is taken orally with or without food once daily. The exact dosage of this medication is to be decided by your prescribing physician. Usually, it is taken as 2 milligrams per day.

When should I avoid taking Prucalax Tablet?

You should avoid taking Prucalax Tablet if you are allergic to it. It should also be avoided if you have a tear in your stomach or intestinal wall, a bowel blockage, or inflammatory conditions of the intestinal wall like Crohn’s disease or ulcerative colitis. Always consult your doctor before starting the medication. The doctor should be informed about any ongoing medication and conditions you have.

Fact Box

Chemical Class

Aminobenzamides

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Selective Serotonin 5-HT4 Receptor Agonists

References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1327.
Prucalopride succinate [EMC SmPC]. London, England: Shire Pharmaceuticals Limited; 2022. [Accessed 28 Jan. 2019] (online) Available from:
Prucalopride [EMC SmPC]. Baggot Street Lower Dublin: Shire Pharmaceuticals; 2022. [Accessed 28 Mar. 2019] (online) Available from:
Prucalopride [Package Insert]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2020. [Accessed 05 Aug. 2023] (online) Available from:
Prucalopride [Summary of Product Characteristics]. Turnhout, Belgium: Sanico NV; 2014.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Kylon Remedies Pvt. Ltd.
Address: Shed No. 17 Parshwanath Estate, Opp. Om Shanti School, B/H CTM Mill, CTM, Ahmedabad-380026. (Guj.) INDIA

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Prucalax Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Prucalax Tablet

Benefits of Prucalax Tablet

Side effects of Prucalax Tablet

How to use Prucalax Tablet

How Prucalax Tablet works

All substitutes for Prucalax Tablet

Pruloford 2mg Tablet

Pruvict 2 Tablet

Presmovac 2 Tablet

Consticalo 2 Tablet

Pruease 2mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Erythromycin (Oral Route)

Erythromycin (Injection Route)

Atropine (Injection Route)

Ciclosporin (Injection Route)

Ciclosporin (Oral Route)

Frequently asked questions

How quickly does Prucalax Tablet work?

Is Prucalax Tablet safe in pregnancy?

When should I take Prucalax Tablet?

When should I avoid taking Prucalax Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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