Prucalopride

Information about Prucalopride

Prucalopride Uses

Prucalopride is used in the treatment of constipation. It helps in relieving constipation that is long-lasting or keeps coming back.

How Prucalopride works

Prucalopride is a selective 5-HT4 receptor agonist that has high intrinsic activity. It indirectly stimulates the release of acetylcholine, a chemical messenger that increases the motility of the intestine and treats even chronic (long-term) constipation very effectively.

Common side effects of Prucalopride

Headache, Nausea, Diarrhea, Abdominal pain, Decreased appetite, Dyspepsia, Abnormal gastrointestinal sound, Dizziness, Vomiting, Flatulence, Fatigue
CONTENT DETAILS
Written By
Dr. Betina Chandolia
MDS, BDS
Reviewed By
Dr. Lalit Kanodia
MBA, MD Pharmacology
Last updated
27 Sep 2022 | 01:22 PM (UTC)

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Available Medicine for Prucalopride

PruvictTorrent Pharmaceuticals Ltd
₹237 to ₹3722 variant(s)
PresmovacTorrent Pharmaceuticals Ltd
₹198 to ₹3652 variant(s)
ConsticaloTorrent Pharmaceuticals Ltd
₹226 to ₹3652 variant(s)
PrueaseSun Pharmaceutical Industries Ltd
₹209 to ₹3592 variant(s)
PruwelIntas Pharmaceuticals Ltd
₹232 to ₹3662 variant(s)
PrudacZydus Cadila
₹163 to ₹2732 variant(s)
DuphaproAbbott
₹181 to ₹2692 variant(s)
PrusentLupin Ltd
₹207 to ₹3862 variant(s)
MuvpruEmcure Pharmaceuticals Ltd
₹149 to ₹2292 variant(s)
PrucaplaCipla Ltd
₹154 to ₹2542 variant(s)

Expert advice for Prucalopride

  • Prucalopride helps treat chronic constipation and improve bowel movements, when laxatives have failed to provide adequate relief.
  • It can be taken with or without food, at any time of the day.
  • It may cause diarrhea. Drink plenty of water and inform your doctor if it bothers you.
  • Inform your doctor if your constipation has not improved even after four weeks of taking this medication.

Frequently asked questions for Prucalopride

Prucalopride

Q. How quickly does Prucalopride work?

Prucalopride has been found to act rapidly but the effect varies from person to person. This is because the response to a particular medication varies in every patient. Usually, the medicine generates a bowel movement within 2-3 hours. However, it may take about 4-5 days to show complete effect and rapid bowel movements.

Q. Is Prucalopride safe in pregnancy?

No, Prucalopride is not safe to be taken during pregnancy. There are few reported cases of spontaneous abortion that have been noted when given in pregnant women. There is little evidence of use of Prucalopride in pregnant women. Therefore, its use during pregnancy should be avoided. It is important to consult your doctor before starting this medication.

Q. When should I take Prucalopride?

Prucalopride can be taken at any time of the day. Normally, it is taken orally with or without food once daily. The exact dosage of this medication is to be decided by your prescribing physician. Usually, it is taken as 2 milligrams per day.

Q. Can Prucalopride cause gastroparesis?

Prucalopride has been proven to be beneficial in cases of gastroparesis and constipation. Gastroparesis is a condition where there is reduced movement of the gut that leads to delayed emptying of the stomach and constipation. Generally, this occurs in conditions like diabetes or after surgery.

Q. When should I avoid taking Prucalopride?

You should avoid taking Prucalopride if you are allergic to it. It should also be avoided if you have a tear in your stomach or intestinal wall, a bowel blockage or inflammatory conditions of the intestinal wall like Crohn’s disease or ulcerative colitis. Always consult your doctor before starting the medication. The doctor should be informed about any ongoing medication and conditions you have.

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