Product introduction
Protolac 20mg Tablet is a medicine that helps reduce the amount of acid made by the stomach. It is used for the treatment of peptic ulcer, gastric ulcer, gastroesophageal reflux disease (GERD), and for the management of Zollinger-Ellison syndrome, a rare condition in which the stomach produces too much acid.
Take Protolac 20mg Tablet exactly as directed by your doctor, usually once daily before a meal. Swallow it whole; do not chew or crush it. To get the most benefit, take it regularly at the same time each day. Continue the full course even if you feel better, as stopping too soon may cause symptoms to return. Along with treatment, avoid irritants such as alcohol, tobacco, and spicy or acidic foods. Eat smaller, more frequent meals and do not lie down immediately after eating.
The most common side effects include headache, stomach pain, nausea, diarrhea, vomiting, and gas. These are generally mild and often go away as your body adjusts to the medicine. If diarrhea is severe, persistent, or watery, inform your doctor. Staying hydrated and maintaining a balanced diet can help reduce discomfort.
Before taking this medicine, tell your doctor if you have liver disease or any kidney problems. Long-term or high-dose use may increase the risk of bone fractures, low vitamin B12 or magnesium levels, or fundic gland polyps in the stomach. Therefore, the medicine should be used at the lowest effective dose for the shortest possible time. Seek immediate help if you notice signs of severe allergic reaction, such as swelling, breathing difficulty, or rash with blisters. Do not take Protolac 20mg Tablet if you are allergic to omeprazole or any ingredients in the medicine. Inform your doctor about all other medicines you take, as Protolac 20mg Tablet can affect how other medicines work.
Uses of Protolac Tablet
- Treatment of Stomach ulcers
- Treatment of Gastroesophageal reflux disease (Acid reflux)
- Treatment of Peptic ulcer disease
- Management of Zollinger-Ellison syndrome
Benefits of Protolac Tablet
In Treatment of Stomach ulcers
In gastric ulcers, Protolac 20mg Tablet lowers acid levels in the stomach, protecting the stomach wall from further damage and giving it time to recover. Regular use as prescribed can help relieve symptoms such as burning pain and discomfort, and promote complete ulcer healing.
In Treatment of Gastroesophageal reflux disease (Acid reflux)
Protolac 20mg Tablet provides relief from the burning sensation of acid reflux and heartburn caused by gastroesophageal reflux disease (GERD). It reduces acid production, preventing stomach acid from flowing back into the food pipe, and helps heal irritation or inflammation of the esophagus, improving comfort and digestion.
In Treatment of Peptic ulcer disease
Protolac 20mg Tablet helps relieve pain and promotes healing in peptic ulcers (duodenal ulcers) by reducing excess stomach acid that irritates the ulcer lining. It blocks acid production and allows the damaged tissue in the stomach and upper intestine to heal properly. It also helps prevent the ulcer from coming back.
In Management of Zollinger-Ellison syndrome
For people with Zollinger-Ellison syndrome, where the stomach produces too much acid, Protolac 20mg Tablet helps control acid secretion and prevents complications such as ulcers. It provides long-term management of acid levels, improving quality of life and preventing damage to the stomach and intestines.
Side effects of Protolac Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Protolac
- Abdominal pain
- Flatulence
- Headache
- Nausea
- Diarrhea
- Vomiting
How to use Protolac Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Protolac 20mg Tablet is to be taken on an empty stomach.
How Protolac Tablet works
Protolac 20mg Tablet works by specifically blocking an enzyme system known as the “acid pump” in the stomach lining. This enzyme is responsible for the final step in the production of gastric acid. Inhibiting this pump reduces both the volume and acidity of stomach secretions, providing lasting acid suppression and promoting healing of acid-related conditions such as ulcers and reflux disease.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Protolac 20mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Protolac 20mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Protolac 20mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Protolac 20mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Protolac 20mg Tablet in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Protolac 20mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Protolac Tablet?
If you miss a dose of Protolac 20mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Take it before a meal, preferably in the morning, 30–60 minutes before breakfast, to get the best effect.
- Take it at the same time every day to help maintain consistent acid control.
- Avoid trigger foods, such as spicy, fatty, or acidic foods, and limit caffeine and alcohol intake.
- Avoid laying down right after eating. Wait at least 2–3 hours after meals before lying down to prevent acid reflux.
- Combine the treamtent with with lifestyle changes, such as healthy weight and quitting smoking.
- If you still experience heartburn or indigestion after 2 weeks, consult with your doctor.
Fact Box
Chemical Class
Sulfinylbenzimidazoles
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors
Interaction with drugs
Taking Protolac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Do not consume Atazanavir with Omeprazole. If concurrent use is essential, please consult your doctor. Omeprazole may reduce blood levels of Atazanavir.
Your doctor may monitor your treatment and adjust the doses as per the observations. Omeprazole may raise blood levels of Voriconazole.
Voriconazole may raise blood levels of Omepr
Do not consume Erlotinib with Omeprazole. Omeprazole may reduce blood levels of Erlotinib.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Patient concerns
FAQs
What is Protolac 20mg Tablet used for?
Protolac 20mg Tablet is used to treat several acid-related stomach and intestinal conditions such as peptic ulcer, gastric ulcer, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It helps relieve heartburn, heals ulcers, and prevents damage caused by excess acid in the stomach and food pipe.
How long does Protolac 20mg Tablet take to work?
Some people begin to feel better within a few days, but it may take up to 4 weeks for full relief. Most ulcers and reflux symptoms heal within 4 to 8 weeks of treatment, depending on your condition.
Can I take Protolac 20mg Tablet every day?
Yes, Protolac 20mg Tablet can be taken daily as prescribed. However, prolonged or unnecessary use should be avoided. Long-term use may increase the risk of bone fractures, vitamin B12 deficiency, magnesium imbalance, or fundic gland polyps. Use the lowest effective dose for the shortest duration necessary.
Can I take Protolac 20mg Tablet with other medicines?
Some medicines can interact with Protolac 20mg Tablet. Do not take it with rilpivirine-containing medicines. Avoid combining it with St. John’s Wort or rifampin, as these can reduce its effectiveness. This medicine may also affect the way clopidogrel, warfarin, methotrexate, and digoxin work. Always inform your doctor about all other medicines or supplements you use.
Is Protolac 20mg Tablet safe during pregnancy or while breastfeeding?
Studies have not shown an increased risk of birth defects with Protolac 20mg Tablet use during pregnancy. It may be used if clearly needed under medical advice. Small amounts may pass into breast milk, but no harmful effects have been reported in infants. Always consult your doctor before use if you are pregnant or breastfeeding.
Can I stop taking Protolac 20mg Tablet once I feel better?
Do not stop taking it suddenly without consulting your doctor. Stopping early may cause your symptoms to return or worsen. Complete the full treatment course as directed.
What should I avoid while taking Protolac 20mg Tablet?
Avoid drinking alcohol, smoking, or eating spicy and fatty foods, as these can worsen acid-related symptoms. Do not take it with rilpivirine or herbal products such as St. John’s Wort, as they may interfere with treatment.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Omeprazole [Prescribing Information]. Columbus, Ohio: American Health Packaging; 2025. [Accessed 28 Oct. 2025] (online) Available from:
- Omeprazole [Prescribing Information]. Auckland, New Zealand: Teva Pharma (New Zealand) Limited; 2024. [Accessed 28 Oct. 2025] (online) Available from:
Marketer details
Name: USV Ltd
Address: Arvind Vithal Gandhi Chowk, BSD Marg, Station Road, Govandi East, Mumbai - 400 088. , India.
Country of origin: India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Protolac 20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: February, 2026
A licensed vendor partner from your nearest location will deliver Protolac 20mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹51.56 11% OFF
₹45.9
Inclusive of all taxes
15.0 tablets in 1 strip
New GST benefit included in this MRP, may differ from label
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