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Prota 10mg Injection

Protamine sulfate (10mg)
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Prota 10mg Injection is a medicine which is used in the treatment of heparin overdose. It neutralizes the anti-blood clotting effect of heparin and stops excessive bleeding.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 08 May 2026 | 03:58 PM (IST)
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Prota 10mg Injection image
Prota 10mg Injection image

Product introduction

Prota 10mg Injection is used to stop bleeding in patients caused by heparin

Uses of Prota Injection

  • Heparin overdose

Benefits of Prota Injection

Heparin overdose
Heparin overdose can lead to excessive bleeding because it thins the blood more than needed, which may occur during or after surgery or medical treatment. Prota 10mg Injection helps stop the bleeding by reversing the effects of heparin. It stabilizes the blood’s ability to clot properly, reducing the risk of serious bleeding complications and supporting a safe and quicker recovery.

Side effects of Prota Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Prota
  • Injection site reactions (pain, swelling, redness)

How to use Prota Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Prota Injection works

Prota 10mg Injection is used to counteract the anticoagulant effect of heparin and is used to stop bleeding in patients caused by heparin.

All substitutes for Prota 10mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Prota 10mg Injection helps neutralize the effect of anti-clotting medicine heparin.
  • It should not be used to reverse the effects of other anti-clotting medicines (anticoagulants) such as warfarin.
  • It should be used under medical supervision. Do not self-administer.
  • Inform your doctor if you experience a sudden fall in blood pressure, breathlessness, or chest and abdominal pain when receiving Prota 10mg Injection.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Prota 10mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Prota 10mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Prota 10mg Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CAUTION
Prota 10mg Injection may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Prota 10mg Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Prota 10mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Yes. Protamine sulphate is used as an antidote in the case of overdose of lovenox.
When administered alone, protamine has an anticoagulant effect. However, when it is given in the presence of heparin, a stable salt is formed and the anticoagulant activity of both drugs is lost

Fact Box

Chemical Class

Peptides

Habit Forming

No

Therapeutic Class

OTHERS

Action Class

Heparin Antagonists

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1167-68.
  2. Protamine. Lake Zurich, Illinois: Fresenius Kabi; 2016. [Accessed 06 Apr. 2019] (online) Available from:
  3. Protamine sulfate. Wrexham: Wockhardt UK Ltd.; 1991 [revised 4 May 2018]. [Accessed 6 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Samarth Life Sciences Pvt Ltd
Address: Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Prota 10mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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