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Premarin Vaginal Cream
Prescription Required
Product introduction
Premarin Vaginal Cream is a female sex hormone (estrogen). It is a part of female hormone replacement therapy which helps in treating estrogen deficiency symptoms like hot flushes (red and warm face) and vaginal dryness.
In some cases, Premarin Vaginal Cream is also used to treat breast cancer and prostate cancer along with other anticancer medicines. It is to be taken at a fixed time(s) daily. The dose and duration will be decided by your doctor so that you get the right amount to control your symptoms. If you have missed a dose, take it as soon as you remember it. Do not skip any dose and finish the full course of treatment. The treatment should not be stopped abruptly without consulting your doctor as this may affect the potency of this medicine.
The most common side effects of this HRT are headaches, breast pain, irregular vaginal bleeding or spotting, abdominal cramps or bloating, and vomiting. Some of the warning signs and symptoms that need immediate medical attention are breast lumps, unusual vaginal bleeding, dizziness and faintness, severe headaches, chest pain, shortness of breath, pains in your legs, etc.
Before taking this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Before you initiate with this HRT, you must consult the doctor if you have a history of unexplained vaginal bleeding or if you have ever had a blood clot in your legs or your lungs. If you are pregnant or breastfeeding, you should tell your doctor before taking this medicine. Your doctor may suggest you some diagnostic or laboratory tests to know the effects and side effects of this medicine on your body.
Uses of Premarin Vaginal Cream
Benefits of Premarin Vaginal Cream
In Hormone replacement therapy
Hormone placement therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Estrogen is one of two important hormones (the other is progesterone) used in this treatment. Vaginal tablets and gels are an easy way to deliver hormones but may not treat all the symptoms. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.
Side effects of Premarin Vaginal Cream
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Premarin
- Abnormal vaginal bleeding
- Irritation
- Pelvic pain
- Breast pain
- Irregular vaginal bleeding
- Edema (swelling)
- Vaginal spotting
- Vaginal itching
- Depression
- Leg cramps
- Abdominal cramp
- Vaginal burning sensation
How to use Premarin Vaginal Cream
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream by using applicator. Wash your hands after applying.
How Premarin Vaginal Cream works
Premarin Vaginal Cream is a mixture of estrogens (a female sex hormone). As a part of the hormone replacement therapy, it works by maintaining the estrogen levels in the body in menopausal women. It also prevents the vaginal wall from becoming thin and dry thereby reducing inflammation.
Safety advice
Alcohol
No interaction found/established
Pregnancy
CONSULT YOUR DOCTOR
Premarin Vaginal Cream is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Premarin Vaginal Cream is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
No interaction found/established
Kidney
No interaction found/established
Liver
No interaction found/established
What if you forget to take Premarin Vaginal Cream?
If you miss a dose of Premarin Vaginal Cream, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- You have been prescribed Premarin Vaginal Cream as a part of hormone replacement therapy to relieve symptoms of menopause.
- It can be applied to the external vaginal area, or inserted into the vagina using the applicator provided.
- It does not expose the rest of your body to the medicine thereby avoiding side effects that happen more often with pills.
- Do not have sex right after using Premarin Vaginal Cream as some of the medicine can be absorbed into your partner's skin.
- Inform your doctor if you experience any vaginal bleeding or spotting, abnormal vaginal discharge or vaginal discomfort while using this medicine.
- Do not use Premarin Vaginal Cream if you are pregnant or breastfeeding, over 35, smoke, or have a history of blood clots or heart diseases.
Fact Box
Chemical Class
Estradiol Congeners
Habit Forming
No
Therapeutic Class
GYNAECOLOGICAL
Interaction with drugs
Taking Premarin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Altrom, Cenorol, Cgtrom
Life-threatening
Brand(s): Fetrop, Fertitone, Pifert
Life-threatening
Brand(s): Donogen, Gonablok, Danzox
Life-threatening
Brand(s): Xemasin
Life-threatening
Patient concerns
User feedback
Patients taking Premarin Vaginal Cream
Once A Day
72%
Twice A Day
14%
Alternate Day
4%
Twice A Week
4%
Once A Week
2%
Thrice A Day
2%
Thrice A week
1%
What are you using Premarin Vaginal Cream for?
Others
48%
Hormone repla*
26%
Dryness in va*
22%
Contraception
4%
*Hormone replacement therapy, Dryness in vagina
How much was the improvement?
Average
42%
Excellent
30%
Poor
27%
What were the side-effects while using Premarin Vaginal Cream?
No Side Effec*
100%
*No Side Effect
How do you take Premarin Vaginal Cream?
With or witho*
100%
*With or without food
Please rate Premarin Vaginal Cream on price
Average
78%
Not Expensive
22%
FAQs
Q. What is Premarin Vaginal Cream and what it is used for?
Premarin Vaginal Cream is a vaginal cream, which contains a mixture of estrogens (a female sex hormones). It is used to treat vaginal problems (itching, dryness, and irritation) caused due to lack of estrogen. It may also be used as a hormone replacement therapy in postmenopausal women.
Q. How to use Premarin Vaginal Cream?
This type of cream or gel usually comes with an applicator and the directions to use. You must clean and dry the affected area, before applying the cream. Use this medicine only as advised by your doctor. Do not use more than you have been advised.
Q. What if I forget to use Premarin Vaginal Cream?
You may apply the missed dose as soon as you remember unless you are not 12 hours late. If you are more than 12 hours late, then skip the missed dose and follow the usual dosing schedule.
Q. What are the common side effects of using Premarin Vaginal Cream?
The side effects of using Premarin Vaginal Cream are rare. However, initially, you may feel irritation or itching of the skin in or around the vagina, which usually gets better after a few weeks. Other side effects may include a headache, flu-like symptoms, skin rash, pain in breasts, and increased vaginal discharge. Most of these symptoms are temporary, however, if these persist, consult with your doctor.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 501.
- Conjugated estrogens. Philadelphia, PA: Wyeth Pharmaceuticals LLC; 1946 [revised Sep. 2018]. [Accessed 21 Jun. 2019] (online) Available from:
- RxList. Conjugated estrogens vaginal cream. [Accessed 21 Jun. 2019] (online) Available from:
- Conjugated estrogens [Prescribing Information]. Philadelphia, PA: Wyeth Pharmaceuticals Inc.; 2017. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Pfizer Ltd
Address: The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051.
Country of origin: Canada
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Premarin Vaginal Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Premarin Vaginal Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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