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Pramirol 1 Tablet

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Overview

Introduction

Pramirol 1 Tablet is a prescription medicine used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements.

Pramirol 1 Tablet should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.

Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble or uncontrolled spending as these may prove very harmful.

Uses of Pramirol Tablet

  • Parkinson's disease
  • Restless leg syndrome

Side effects of Pramirol Tablet

Common
  • Dizziness
  • Sleepiness
  • Nausea
  • Dryness in mouth
  • Fatigue
  • Hallucination
  • Constipation
  • Peripheral edema

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Dizziness
    This is usually short-lived and should go away within a few days. If this happens, stop what you are doing and sit or lie down until you feel better. Lying still in a dark, quiet room may help reduce the spinning feeling. Sleep with your head slightly raised on two or more pillows. Get up slowly from a lying or sitting position. Get plenty of rest and try to relax as being anxious can make it worse. Try taking this medicine at bedtime to reduce the symptoms. Drinking plenty of water and ginger tea may also help. Avoid alcohol, caffeine and smoking as it will make you feel worse. Avoid driving or using tools or machinery until you feel better.
  • Coping with Sleepiness
    If the medicine is making you drowsy during the day, stop what you are doing and sit or lie down until you feel better. You can also consider taking a nap. Physical exercises such as walking may be helpful. Do not drink alcohol, as it will make you feel more tired. Avoid driving or operating heavy equipment when you are feeling drowsy. This problem usually goes away as your body gets used to the medicine. However, if it does not, ask your doctor if you can take your medicine at bedtime or whether the dose can be reduced.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Dryness in mouth
    Keep a drink available that you can sip through the day. Rinse your mouth with warm salted water and chew sugarless gum or hard candy. Try breathing through your nose more often than your mouth. Avoid caffeinated beverages, smoking and alcohol because they can make your condition worse. Use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy, salty or sugary. If this side effect bothers you or does not go away, talk to your doctor about artificial saliva products or other suitable treatments.
  • Coping with Constipation
    Try to eat foods which are high in fiber such as fresh fruits, vegetables and cereals to increase the bulk and consistency of bowel movements. Drink plenty of water or non-alcoholic drinks and stay hydrated to promote healthy digestion. Increasing physical activities such as walking, yoga and regular exercise can also be helpful. If your condition does not improve, you can ask your doctor to prescribe you laxative medicine.

How to use Pramirol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pramirol 1 Tablet is to be taken with food.

How Pramirol Tablet works

Pramirol 1 Tablet works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.

Safety Advice

Alcohol
UNSAFE
Pramirol 1 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Pramirol 1 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Pramirol 1 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pramirol 1 Tablet suppresses serum prolactin and may interfere with breastfeeding.
Driving
UNSAFE
Pramirol 1 Tablet may cause side effects which could affect your ability to drive.
Pramirol 1 Tablet can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.
Kidney
CAUTION
Pramirol 1 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pramirol 1 Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pramirol 1 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pramirol 1 Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
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Quick Tips

  • You have been prescribed Pramirol 1 Tablet to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
  • It can be taken with or without food. Taking it with food may reduce nausea.
  • For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
  • Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
  • When you first start taking Pramirol 1 Tablet, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.
  • Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
  • Do not stop taking the medication suddenly without talking to your doctor.

Interaction with Drugs

Taking Pramirol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Karzine, Ostil, Prom
LIFE-THREATENING
Brand(s): Pnxol, Flupen, Full ON
LIFE-THREATENING
Brand(s): Medipax, Monazine, Prolinate
LIFE-THREATENING
Brand(s): Cizonil
LIFE-THREATENING

Patient Concerns

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For restless leg syndrome doctor?
Dr. Vikas Sharma
Neurology
Tab pramirol 0.25 mg in evening daily
restless leg syndrome urgue move leg in night
Dr. Vikas Sharma
Neurology
start tab pramirol 0.25 mg at nite
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Do you have any questions related to Pramirol 1 Tablet ?

User Feedback


FAQs

Q. Does Pramirol cause weight gain?

A common side effect of Pramirol is decrease in body weight which may be due to decrease in appetite. Uncommonly, it can also cause increase in weight. However, if you have concerns regarding your weight talk to your doctor or a nutritionist.

Q. Does Pramirol make you sleepy?

Yes, Pramirol may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery and inform your doctor.

Q. How does Pramirol work for restless legs?

Restless leg syndrome (RLS) is a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down. Pramirol belongs to dopamine (neurotransmitter) agonist class of medicines. It acts by stimulating the dopamine receptors which is needed in the brain to control movement. Hence, it is used to improve RLS.

Q. Is Pramirol a muscle relaxant?

No, Pramirol is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.

Q. Can I stop taking Pramirol if my symptoms of Parkinson’s disease have improved?

You should not stop Pramirol without talking to your doctor. Sudden discontinuation of Pramirol may cause neuroleptic malignant syndrome. The symptoms of malignant syndrome include loss of muscle movement, rigid muscles, fever, unstable blood pressure, increased heart rate, confusion, and depressed level of consciousness.

Q. How should Pramirol be taken?

You should take Pramirol as directed by your doctor. The doctor will decide your dose depending on the condition you are being treated for. Preferably it should be taken 2-3 hours before bedtime. Swallow the tablets whole with water. It can be taken with or without food, but taking it with food may help reduce the chances of nausea.

Q. What are the serious side effects of Pramirol?

The serious side effects of Pramirol include hallucinations (seeing things or hearing voices that do not exist), confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, abnormal body movements, and motions that you cannot control. It may also cause changes in the way you sit or stand that you cannot control, such as your neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand or walk. Additionally, it may cause dark, red or cola-colored urine, muscle tenderness, muscle stiffness or aching and muscle weakness. Call your doctor immediately if you experience any of these.

Q. What are impulse control disorders caused by Pramirol?

Pramirol may cause impulse control disorders in which you may have cravings or urge to behave in an unusual manner, which normally you would not do. Pramirol may also make it hard for you to resist the impulse to carry certain activities which can harm you or others, like addictive gambling, excessive eating or spending money. Along with that, it may cause an abnormally high sex drive or preoccupation with an increase in sexual thoughts or feelings.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 475-76.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1140-41.
  3. Pramipexole dihydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim International GmbH; 2010. [Accessed 22 Jan. 2019] (online) Available from:External Link
  4. Drugs.com. Pramipexole. [Accessed 22 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:External Link
  6. Pramipexole. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 7 Feb. 2018]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
A licensed vendor partner from your nearest location will deliver Pramirol 1 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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