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Pramipex ER 0.375 Tablet

Prescription Required
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)
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Introduction

Pramipex ER 0.375 Tablet is a prescription medicine used in the treatment of Parkinson's disease and restless leg syndrome (an urge to move the legs usually accompanied or caused by uncomfortable and unpleasant leg sensations). It helps to treat excessive shaking by slowing down the body movements.

Pramipex ER 0.375 Tablet should be taken with food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. You should never skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor.

Some common side effects of this medicine include nausea, dry mouth, fatigue, hallucinations, constipation, and peripheral edema. It also causes dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Inform your doctor if you develop any unusual changes in mood, an abnormally high sex drive, an urge to gamble or uncontrolled spending as these may prove very harmful.

Side effects of Pramipex Tablet ER

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pramipex

  • Dizziness
  • Sleepiness
  • Nausea
  • Dryness in mouth
  • Fatigue
  • Hallucination
  • Constipation
  • Peripheral edema

How to use Pramipex Tablet ER

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pramipex ER 0.375 Tablet is to be taken with food.

How Pramipex Tablet ER works

Pramipex ER 0.375 Tablet works by increasing the action of dopamine, a chemical messenger that is needed to control movement in the brain.

Safety Advice

Alcohol
UNSAFE
Pramipex ER 0.375 Tablet may cause excessive drowsiness with alcohol.
Pregnancy
CONSULT YOUR DOCTOR
Pramipex ER 0.375 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Pramipex ER 0.375 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Pramipex ER 0.375 Tablet suppresses serum prolactin and may interfere with breastfeeding.
Driving
UNSAFE
Pramipex ER 0.375 Tablet may cause side effects which could affect your ability to drive.
Pramipex ER 0.375 Tablet can cause hallucinations (seeing, hearing or feeling things that are not there). This may affect your ability to drive.
Kidney
CAUTION
Pramipex ER 0.375 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pramipex ER 0.375 Tablet may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Pramipex ER 0.375 Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Pramipex ER 0.375 Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Pramipex ER 0.375 Tablet
₹9.0/Tablet ER
Mirapex 0.375mg Tablet ER
Boehringer Ingelheim
₹6.25/Tablet ER
save 31%

Quick Tips

  • You have been prescribed Pramipex ER 0.375 Tablet to treat your symptoms of Parkinson's disease and/or restless leg syndrome.
  • It can be taken with or without food. Taking it with food may reduce nausea.
  • For restless leg syndrome, take this medicine 2 to 3 hours before bedtime.
  • Avoid activities that require you to be alert, such as driving a car until you know how this medication affects you.
  • When you first start taking Pramipex ER 0.375 Tablet, it may cause sudden drop in your blood pressure when you change positions. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Talk to your doctor in case you develop hallucinations or other changes in your behavior.
  • Inform your doctor if you develop compulsive behaviors that are hard to control, such as binge eating, gambling, spending money, and sexual urges.
  • Do not stop taking the medication suddenly without talking to your doctor.

Fact Box

Chemical Class
Benzothiazole Derivative
Habit Forming
No
Therapeutic Class
NEURO CNS

Interaction with Drugs

Taking Pramipex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Karzine, Ostil, Prom
LIFE-THREATENING
Brand(s): Pnxol, Full ON, Restzone
LIFE-THREATENING
Brand(s): Medipax, Phenodec, Flyzox
LIFE-THREATENING
Brand(s): Cizonil
LIFE-THREATENING

Patient Concerns

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I feel tingling in my legs,whenever i close my eyes.rls is the name of disease.i want treatment, as i am taking pramipex 1mg twice a day Plz guide me properly
Dr. Jyoti Kapoor Madan
Psychiatry
Restless Leg Syndrome or RLS is a neurological disorder. Pramipexol is a treatment modality. Your neurologist can advise you about other options if it doesn't work for you.
Post L5 S1 surgery my right leg numbness still persist. As per advise taking lyrica 75 mg n evion LC daily. But no use pls advise
Dr. Vikas Sharma
Neurology
try tab pramipex 0.25 mg HS
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FAQs

Q. Does Pramipex ER 0.375 Tablet cause weight gain?

A common side effect of Pramipex ER 0.375 Tablet is decrease in body weight which may be due to decrease in appetite. Uncommonly, it can also cause increase in weight. However, if you have concerns regarding your weight talk to your doctor or a nutritionist.

Q. Does Pramipex ER 0.375 Tablet make you sleepy?

Yes, Pramipex ER 0.375 Tablet may cause sleepiness. You may also experience sudden episodes of falling asleep. If it occurs, restrict driving and using heavy machinery and inform your doctor.

Q. How does Pramipex ER 0.375 Tablet work for restless legs?

Restless leg syndrome (RLS) is a condition that causes discomfort in the legs and a strong urge to move the legs, especially at night and when sitting or lying down. Pramipex ER 0.375 Tablet belongs to dopamine (neurotransmitter) agonist class of medicines. It acts by stimulating the dopamine receptors which is needed in the brain to control movement. Hence, it is used to improve RLS.

Q. Is Pramipex ER 0.375 Tablet a muscle relaxant?

No, Pramipex ER 0.375 Tablet is not a muscle relaxant. It helps in improving movements and muscle control in Parkinson’s disease. It is a dopamine agonist and acts on dopamine receptors.

Q. Can I stop taking Pramipex ER 0.375 Tablet if my symptoms of Parkinson’s disease have improved?

You should not stop Pramipex ER 0.375 Tablet without talking to your doctor. Sudden discontinuation of Pramipex ER 0.375 Tablet may cause neuroleptic malignant syndrome. The symptoms of malignant syndrome include loss of muscle movement, rigid muscles, fever, unstable blood pressure, increased heart rate, confusion, and depressed level of consciousness.

Q. How should Pramipex ER 0.375 Tablet be taken?

You should take Pramipex ER 0.375 Tablet as directed by your doctor. The doctor will decide your dose depending on the condition you are being treated for. Preferably it should be taken 2-3 hours before bedtime. Swallow the tablets whole with water. It can be taken with or without food, but taking it with food may help reduce the chances of nausea.

Q. What are the serious side effects of Pramipex ER 0.375 Tablet?

The serious side effects of Pramipex ER 0.375 Tablet include hallucinations (seeing things or hearing voices that do not exist), confusion, aggressive behavior, agitation, abnormal thoughts, changes in vision, abnormal body movements, and motions that you cannot control. It may also cause changes in the way you sit or stand that you cannot control, such as your neck bending forward, bending forward at the waist, or tilting sideways when you sit, stand or walk. Additionally, it may cause dark, red or cola-colored urine, muscle tenderness, muscle stiffness or aching and muscle weakness. Call your doctor immediately if you experience any of these.

Q. What are impulse control disorders caused by Pramipex ER 0.375 Tablet?

Pramipex ER 0.375 Tablet may cause impulse control disorders in which you may have cravings or urge to behave in an unusual manner, which normally you would not do. Pramipex ER 0.375 Tablet may also make it hard for you to resist the impulse to carry certain activities which can harm you or others, like addictive gambling, excessive eating or spending money. Along with that, it may cause an abnormally high sex drive or preoccupation with an increase in sexual thoughts or feelings.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Aminoff MJ. Pharmacologic Management of Parkinsonism & Other Movement Disorders. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 475-76.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1140-41.
  3. Pramipexole dihydrochloride. Ridgefield, Connecticut: Boehringer Ingelheim International GmbH; 2010. [Accessed 22 Jan. 2019] (online) Available from:External Link
  4. Drugs.com. Pramipexole. [Accessed 22 Mar. 2019] (online) Available from:External Link
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 22 Mar. 2019] (online) Available from:External Link
  6. Pramipexole. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 7 Feb. 2018]. [Accessed 22 Mar. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 22 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

90, Delhi - Jaipur Road, Sector 32, Gurugram, Haryana 122001
Expires on or after: December, 2021

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