Posafung 300mg Injection

Posaconazole (300mg)

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Posafung 300mg Injection is an antifungal medicine used to prevent and treat severe fungal infections, particularly in people with weakened immune systems. It is commonly prescribed to prevent invasive infections caused by Aspergillus and Candida species and to treat fungal infections of the mouth and throat.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 24 Jun 2026 | 11:39 AM (IST)

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General Information

Contains

Posaconazole (300mg)

Marketer

Gufic Bioscience Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Do not self-administer this medicine. Your doctor or nurse will teach you the correct way of injecting it. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment.

The most common side effects of this medicine include diarrhea, nausea, fever, vomiting, headache, coughing, and hypokalemia. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction and signs of liver problems such as yellowing of eyes, dark urine, and stomach problems. Get emergency help if this happens.

Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver, and potassium level by testing your blood. This medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.

Uses of Posafung Injection

Treatment of Severe fungal infections

Benefits of Posafung Injection

Treatment of Severe fungal infections
Posafung 300mg Injection is an antifungal medicine used to treat serious fungal infections. It is especially beneficial for patients who are severely immunocompromised, such as those with cancer or those undergoing chemotherapy or blood transfusions. This medicine is administered by a doctor or a nurse and should not be self-administered. The dose and duration of treatment will be determined by your doctor based on your condition. It is important to complete the full course of treatment, even if you start feeling better, to ensure the infection is fully cleared and does not return.

Side effects of Posafung Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Posafung

Fever
Decreased potassium level in blood
Diarrhea
Vomiting
Headache
Nausea
Cough
Increased calcium level in blood

How to use Posafung Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Posafung Injection works

Posafung 300mg Injection is an antifungal that works by inhibiting the enzyme essential for the synthesis of ergosterol, a key component of fungal cell membranes. It disrupts the production of ergosterol, damaging the fungal cell membrane, leading to cell death. This action makes it effective in preventing and treating invasive Aspergillus and Candida infections in immunocompromised patients, as well as treating oropharyngeal candidiasis, including cases resistant to other azoles like itraconazole or fluconazole.

All substitutes for Posafung 300mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Do not skip any doses and finish the full course of treatment even if you feel better.
It is given as an injection under the supervision of a healthcare professional.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Posafung 300mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Posafung 300mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Posafung 300mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Posafung 300mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
As you may feel dizzy, sleepy, or have blurred vision while taking Posafung 300mg Injection, which may affect your ability to drive.

Kidney

CAUTION

Posafung 300mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is advised while taking this medicine. Use of Posafung 300mg Injection is not recommended in patients with moderate to severe kidney disease.

Liver

CAUTION

Posafung 300mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Posafung with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Simvastatin (Oral Route)

Do not consume Simvastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Simvastatin. Posaconazole may raise blood levels of Simvastatin.

Life-threatening

Lovastatin (Oral Route)

Do not consume Lovastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Lovastatin. Posaconazole may raise blood levels of Lovastatin.

Severe

Atorvastatin (Oral Route)

Do not consume Atorvastatin with Posaconazole. If concurrent use is essential, watch out for symptoms such as muscle pains or weakness and consult your doctor if you experience them. They may adjust the doses as per the observations.

Severe

Ranolazine (Oral Route)

Do not consume Ranolazine with Posaconazole. If concurrent use is essential, watch out for symptoms of Ranolazine side effects such as nausea, vomiting, headache, dizziness, constipation or weakness and consult your doctor if you experience them. They may adjust the dose of Ranolazine accordingly. Posaconazole may raise blood levels of Ranolazine.

Severe

Pimozide (Oral Route)

Do not consume Pimozide with Posaconazole.

Frequently asked questions

How is Posafung 300mg Injection administered?

Posafung 300mg Injection is administered under the supervision of a trained healthcare professional or a doctor and should not be self administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Posafung 300mg Injection.

What is Posafung 300mg Injection, and what is it used for?

Posafung 300mg Injection belongs to a class of medicines known as antifungal agents. It is used to treat serious fungal infections caused by organisms such as Aspergillus and Candida, particularly in patients who are at high risk of developing these infections. Posafung 300mg Injection is mainly prescribed to severely immunocompromised individuals, such as those with cancer or those undergoing chemotherapy or blood transfusions.

How is Posafung 300mg Injection administered?

Posafung 300mg Injection is administered under the supervision of a doctor or nurse and should not be self-administered. The dose depends on the condition being treated and will be determined by your doctor. It is important to follow your doctor’s instructions carefully to gain the maximum benefit from Posafung 300mg Injection.

Is Posafung 300mg Injection effective?

Posafung 300mg Injection is effective when used in the dose and duration prescribed by your doctor. Do not stop taking it even if your symptoms improve. Stopping the medication too early may cause the infection to return or worsen.

What are the side effects of Posafung 300mg Injection?

Some common side effects of Posafung 300mg Injection include cough, headache, nausea, and vomiting. These side effects are generally mild and tend to resolve on their own. However, consult your doctor if any of these symptoms persist or cause concern.

Fact Box

Chemical Class

Phenylpiperazines

Habit Forming

Action Class

Fungal Ergosterol Synthesis Inhibitor

References

Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1581-82.
Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1135-36.
Posaconazole. White House Station, New Jersey: Merck & Co.; 2015. [Accessed 29 Mar. 2019] (online) Available from:
Posaconazole. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2005 [revised 6 Jul. 2018]. [Accessed 29 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gufic Bioscience Ltd
Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Posafung 300mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Posafung Injection

Benefits of Posafung Injection

Side effects of Posafung Injection

How to use Posafung Injection

How Posafung Injection works

All substitutes for Posafung 300mg Injection

Posanat 300mg Injection

Posalup Injection

Candipoz 300mg Injection

Picasa 300mg Injection

Posaone 300mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Simvastatin (Oral Route)

Lovastatin (Oral Route)

Atorvastatin (Oral Route)

Ranolazine (Oral Route)

Pimozide (Oral Route)

Frequently asked questions

How is Posafung 300mg Injection administered?

What is Posafung 300mg Injection, and what is it used for?

How is Posafung 300mg Injection administered?

Is Posafung 300mg Injection effective?

What are the side effects of Posafung 300mg Injection?

Fact Box

Chemical Class

Habit Forming

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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