Medicine Overview of Pletoz Tablet
Side effects of Pletoz Tablet
Headache, Palpitations, Abnormal stool, Diarrhoea, Dizziness, Chest pain, Loss of appetite, Bleeding, Rash.
How to use Pletoz Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pletoz 50mg Tablet is to be taken empty stomach.
How Pletoz Tablet works
Pletoz 50mg Tablet widens the blood vessels and decreases the stickiness of the platelets which increases blood flow to the lower limbs.
In Depth Information on Pletoz Tablet
Expert advice for Pletoz Tablet
- Take cilostazol tablet 1-2 hours before or after meals. minutes before breakfast and the evening meal.
- Do not drive or use machinery that required you to be alert because you may feel sleepy or dizzy while being treated with cilostazol.
- Do not take cilostazol, if you have congestive heart failure. Cilostazol can make this condition worse.
- It may take up to 12 weeks of using cilostazol before your symptoms improve. For best results, keep using the medication as directed.
- Consult your doctor, if your symptoms do not improve after 4 weeks of treatment.
Pletoz Tablet related warnings
Special precautions for Pletoz Tablet
Interaction with alcohol is unknown. Please consult your doctor.
WEIGH RISKS VS BENEFITS
Pletoz 50mg Tablet may be unsafe to use during pregnancy.+more
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor....
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Pletoz 50mg Tablet is probably unsafe to use during lactatio+more
n. Limited human data suggest that the drug could represent a significant risk to the baby....
Pletoz 50mg Tablet may make you feel dizzy, sleepy, tired, o+more
r decrease alertness. If this happens, do not drive....
Pletoz 50mg Tablet should be used with caution in patients w+more
ith severe kidney disease. Dose adjustment of Pletoz 50mg Tablet may be needed. Please consult your doctor....
Pletoz 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Pletoz 50mg Tablet may be needed. Please consult your doctor.+more
Use of Pletoz 50mg Tablet is not recommended in patients with moderate and severe liver disease as the information available in these patients is limited....
Use of Pletoz 50mg Tablet is not recommended in patients with moderate and severe liver disease as the information available in these patients is limited.
Severely interacts with other drugs like
Itragreat 100mg Capsule, Flutis 150mg Tablet, Onecan 400mg Tablet, Flugee 150mg Tablet
If you miss a dose of Cilostazol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Frequently asked questions about Pletoz Tablet
Frequently asked questions about Cilostazol
Pletoz is used as a maintenance therapy for Raynaud's phenomenon in patients with systemic sclerosis. Raynaud's phenomenon is characterized by spasm of blood vessels of extremities causing pale to blue to red sequence of color changes of fingers mainly after exposure to cold. Pletoz is helpful in this condition because of its vasodilating properties.
Pletoz is not used for the treatment of erectile dysfunction. It is a vasodilator and inhibits platelet aggregation. It is used to treat peripheral vascular disease.
Use of Pletoz is contraindicated in patients with severe renal disease because its metabolite levels are increased in these patients and can cause harmful effects. It can be used safely in patients with mild to moderate renal disease.
Peripheral vascular disease is associated with intermittent claudication which causes pain, cramping, numbness, or weakness in the legs while walking. This occurs due to blockage of arteries and insufficient blood flow to legs. Pletoz increases blood flow and reduces the symptoms of intermittent claudication by widening the arteries and keeping the blood thin (does not allow platelets to stick together and form clots).
Q. Is it advisable to take Pletoz with clarithromycin?
Clarithromycin can increase the level or effect of Pletoz by blocking its breakdown (inhibits metabolism). The dose of Pletoz may need to be adjusted if you have to take clarithromycin or other similar antibiotics like erythromycin along with.
Pletoz, when used with aspirin and clopidogrel, was found to be superior compared to aspirin and clopidogrel dual combination in preventing coronary artery restenosis or in-stent thrombosis in patients who underwent percutaneous coronary intervention without increasing the risk of bleeding. However, this is not an approved use and these benefits were seen in some clinical studies.
Pletoz can prevent new episodes of stroke without increasing the risk of bleeding in patients who once had an episode of ischaemic stroke. It is also seen to be effective for primary prevention of stroke in patients with peripheral artery disease. However, these are not approved uses and the benefits were seen in some clinical studies.
Pletoz decreases the muscle pain or cramps that occur during exercise in patients with intermittent claudication. Pletoz can improve exercise capacity as judged by changes in maximal walking distance and pain-free walking distance.
Pletoz is contraindicated in patients with blood, and clotting disorders, heart failure or active pathologic bleeding like bleeding peptic ulcer and intracranial bleeding and known or suspected hypersensitivity to Pletoz or any of its components.
Pletoz should be stopped at least five days before surgery if the antiplatelet effect is not needed during the surgery. Due to reversible antiplatelet action and short half-life (11-13 h) of Pletoz, the risk of surgical bleeding is less and regional anesthesia can be safely administered if it is stopped at least 72 h prior to surgery. However, Pletoz should be stopped only after consulting your doctor and the surgeon.
Q. Can I take Pletoz with sildenafil?
Pletoz can be taken with sildenafil. There are no reported drug interactions or harmful effects when Pletoz is taken along with sildenafil.
Pletoz is to be taken 30 minutes before breakfast or evening meal as food increases the absorption of Pletoz causing an increased incidence of side-effects.
Q. Can I take Pletoz with warfarin?
Pletoz, when taken with warfarin, can increase the risk of bleeding. So they should be used very cautiously and a regular monitoring by your doctor is advisable to decrease the risk of bleeding.
Pletoz is not useful for the management of varicose veins. These are enlarged tortuous veins mainly of the lower limbs. These are treated with compression stockings, sclerotherapy (injecting some substances for closing these veins) or some surgical procedures.
Pletoz, when taken with aspirin, is seen to improve long-term outcomes in patients undergoing percutaneous coronary angioplasty. However, there can be an increased risk of bleeding as both inhibit platelet aggregation and make blood thin. If you are taking Pletoz with aspirin, you should be monitored very closely by your doctor.
Pletoz for RESTenosis (CREST) clinical trial aimed to evaluate the efficacy of Pletoz in inhibiting restenosis after stent implantation. The results showed a significant reduction in the occurrence of restenosis with the use of Pletoz over the standard therapy after coronary stenting.
Q. Can I take Pletoz with ticagrelor?
Pletoz and ticagrelor, when used together, can increase the effects of each other by inhibiting clotting of blood and increasing the risk of bleeding. Avoid taking them together or you should be monitored very closely by your doctor.
Animal studies demonstrate the beneficial role of Pletoz for the treatment of neuropathy. However, human studies do not show any beneficial role of Pletoz in treating neuropathy.
Pletoz is safe if used at prescribed doses for the prescribed duration as advised by your doctor. However, there are some very common side effects that you can experience at therapeutic doses which include a headache, abnormal stool, and diarrhea.
Q. Can I take Pletoz with clopidogrel?
Pletoz, when taken with clopidogrel, is seen to improve long-term outcomes in patients undergoing percutaneous coronary angioplasty. However, there can be an increased risk of bleeding as both inhibit platelet aggregation and make blood thin. If you are taking Pletoz with clopidogrel, you should be monitored very closely by your doctor.
Pletoz is not useful for arterial hypertension. It is used in the management of intermittent claudication associated with peripheral artery disease.
Do not stop Pletoz unless advised by your doctor. Continue to take Pletoz even if you feel better. Stop taking Pletoz only if you experience easy bruising, bleeding, fever or a sore throat and immediately inform your doctor.
Q. Can I take Pletoz with omeprazole?
Omeprazole can increase the level or effect of Pletoz by blocking its breakdown (inhibits metabolism). Avoid using them together. An alternative medicine should be preferred.
Q. Can I use Pletoz with atorvastatin?
Pletoz can be taken with atorvastatin. No harmful effects or drug interactions have been seen or reported when Pletoz is taken along with atorvastatin.
Pletoz can be used in place of aspirin in patients who have an allergy to a spirin.
Q. Is it advisable to take Pletoz with acenocoumarol?
Pletoz, when taken with acenocoumarol, can increase the risk of bleeding. So they should be used very cautiously and a regular monitoring by your doctor is advisable to decrease the risk of bleeding.
There is no evidence at present which recommends the use of Pletoz in the routine therapy of venous insufficiency.
Pletoz is not useful in lowering the blood sugar levels in patients with diabetes. However, as seen in some clinical studies, it may help in relieving the symptoms of intermittent claudication (pain, cramping, numbness, or weakness in the legs on walking) seen in some patients with diabetes.
Pletoz can increase the patient's heart rate, affect the heart rhythm and there is clinical evidence that it can increase mortality in patients with heart failure. So, Pletoz is contraindicated in these patients.
Pletoz is not an anticoagulant. It is a vasodilator with an anti-platelet aggregatory effect. It works by preventing platelets (blood cells) from sticking together and widens the blood vessels of the legs. This increases the blood flow in the peripheries.
No, Pletoz is not a statin. It is a vasodilator and inhibits platelet aggregation, and is useful in the treatment of peripheral vascular disease.
No, Pletoz is not a blood thinner. It is a vasodilator and inhibits platelet aggregation, and is useful in the treatment of peripheral vascular disease.
No, Pletoz is not a beta blocker. It is a vasodilator and inhibits platelet aggregation, and is useful in the treatment of peripheral vascular disease.
Q. Is Pletoz a better choice for the treatment of intermittent claudication compared to pentoxifylline?
Pletoz is seen to be much better than pentoxifylline for increasing walking distances in patients with intermittent claudication but is associated with increased rates of side effects like a headache, palpitations, and diarrhea.
Pletoz is not a controlled substance. It's a prescription medicine and is available on providing a valid prescription by a doctor.
No, Pletoz is not a narcotic substance. It's a prescription medicine and is available on providing a valid prescription by a doctor.
No, Pletoz is not an anticonception medicine. It is a vasodilator and inhibits platelet aggregation. It is used to treat peripheral vascular disease.
No, Pletoz is not an antibiotic. It is a vasodilator and inhibits platelet aggregation. It is used to treat peripheral vascular disease.
User Submitted Feedback For Pletoz 50mg Tablet
Patients taking Pletoz 50mg Tablet
Twice A Day
Once A Day
Thrice A Day
What were the side-effects while using this medicine?
No Side Effect
How do you take this medicine?
How much was the improvement?
Please rate this medicine on price?
What are you using this medicine for?
Peripheral vascular disease
Survey Participants: 10
“The following are the results of on-going survey on 1mg.com for Pletoz 50mg Tablet. These results only indicate the perceptions of the website users. Please base your medical decisions only on the advice of a doctor or a registered medical professional.”
One of the following vendor pharmacies will deliver Pletoz 50mg Tablet: GNC, SAF, DFP, PVP, NVY, OIP, HRV, RUS, INC, UMP, GPT, BSN, DHR, MAM, AAY, DYG, BBS, SHP, NWP, RSA, LCC, CLT, HGI, SBA, MOM, USF, THP, AAR, PNT, HEX, JVN, EMB, SHM, MAX, ZVP, SWP, GBL, EQN, RHL, TRP, DDR, AVN, SDM, SSA, RJH, ADT, RSS, GTK, RKS, HAT, IPL, WSI, MAK, ARD, JVO, ATP, PTI, JIV, WLC, SAT, 9T9, SHD, SVH, NVL, ENP, OWP, HBV, HMP, KHH, PEN, JMJ, MPC, SBL, MLC, SRG, ATL, DPP, DPL, MMS, SJP, STA, IAD, NDP, NNH, PPR, GPP, SWA, GTC, HIP, DLP, BDN, BIO, MSD, FGH, AYU, OLT, OHM, LHA, RHW, PLT, SCH, BMJ, BTM, AGT, AMR, RPP
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