Sign in to your account
or
By signing in you agree to our
Terms & conditions
 and 
Privacy policy
sold out tag

Pitofen 0.5mg Tablet

Written By Dr. Subita Alagh, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 04 Jan 2026 | 08:37 PM (IST)
Pitofen 0.5mg Tablet is a medicine used for the prevention of migraine. However, it cannot treat an acute attack and will only work to prevent migraines for as long as you continue to take the medicine. This medicine relaxes the brain, preventing migraine headache.
Genuine
Authenticity Assured
Prescription
required
₹33 MRP ₹36.5610% off 
 
 
0
footer-icon
All

Save more with additional offers

offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon

Save more with additional offers

offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
chevron icon
offer icon
Get cashback up to ₹500
Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.
chevron icon
offer icon
Get upto Rs.150 Cashback
Get upto Rs.150 Cashback
chevron icon

General Information

The content is shown in English
Pitofen 0.5mg Tablet image
Pitofen 0.5mg Tablet image

Product introduction

Pitofen 0.5mg Tablet may be taken with or without food, preferably at night. However, it is advisable to take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Do not skip any doses and finish the full course of treatment even if you feel better. If you have missed a dose, take it as soon as you remember it.

Side effects associated with the use of this medicine include sleepiness, dryness in mouth, increased appetite, and nausea. It may also cause weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly to prevent it.

It is important to consult your doctor if you develop a skin rash, muscle aches, tremors, or difficulty moving after taking this medicine. You should avoid alcohol consumption while taking this medicine as it may result in increased sedation. If you are taking this medicine for a long-term, regular monitoring of liver function and vision is recommended.

Uses of Pitofen Tablet

Benefits of Pitofen Tablet

Migraine
Migraine is a neurological condition that causes intense, throbbing headaches often accompanied by nausea, vomiting, and sensitivity to light or sound. These episodes can last for hours or even days, severely disrupting daily life and productivity. Pitofen 0.5mg Tablet helps reduce the frequency, severity, and intensity of migraine attacks, making them more manageable over time. This allows individuals to experience fewer disruptions, enjoy more pain-free days, and maintain a better quality of life.

Side effects of Pitofen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pitofen
  • Nausea
  • Sleepiness
  • Dryness in mouth
  • Increased appetite
  • Dizziness
  • Weight gain

How to use Pitofen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pitofen 0.5mg Tablet may be taken with or without food.

How Pitofen Tablet works

Migraine headaches are thought to result from the dilatation of blood vessels in the head. Pitofen 0.5mg Tablet is a serotonin antagonist. It works by maintaining the level of serotonin (chemical messenger) in the brain and also prevents loss of tone and dilation of blood vessels, thus preventing the migraine headache.

Quick tips

  • You have been prescribed Pitofen 0.5mg Tablet for the prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time every day
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get sufficient sleep and avoid stress
  • It should be taken at night-time before going to bed.
  • It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Pitofen 0.5mg Tablet affects you.
  • You may experience weight gain while on treatment. Monitoring of body weight is required on a regular basis.
  • Notify your doctor if you develop skin rash, muscle aches, tremors, difficulty moving, or abnormal uncontrolled movement.
  • You have been prescribed Pitofen 0.5mg Tablet for the prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time every day
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get sufficient sleep and avoid stress
  • It should be taken at night-time before going to bed.
  • It may cause sleepiness. Don't drive or do anything that requires mental focus until you know how Pitofen 0.5mg Tablet affects you.
  • Notify your doctor if you develop skin rash, muscle aches, tremors, difficulty moving, or abnormal uncontrolled movement.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Pitofen 0.5mg Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Pitofen 0.5mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Pitofen 0.5mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Pitofen 0.5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Pitofen 0.5mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Pitofen 0.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pitofen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Tramadol (Injection Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.
Moderate

Tramadol (Oral Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.
Moderate

Morphine (Oral Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.
Moderate

Codeine (Oral Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.
Moderate

Thalidomide (Oral Route)

If concurrent use is essential, watch out for symptoms of Thalidomide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Yes, Pitofen 0.5mg Tablet causes weight gain. This is because of an increase in appetite. If there is an increase in hunger than usual, you can include fresh low-calorie foods in your diet. These are much healthier than processed high-calorie foods. Your doctor can give you advice about diet as some kind of foods are known to trigger migraine.
Yes, it may cause dry mouth because it has anti-cholinergic side effects, though these effects are relatively weak.
No, Pitofen 0.5mg Tablet does not affect the blood pressure. However, if more than the recommended dose of Pitofen 0.5mg Tablet is taken, low blood pressure may occur.
Yes, Pitofen 0.5mg Tablet makes you sleepy, drowsy, and dizzy. Avoid driving and operating heavy machinery while using Pitofen 0.5mg Tablet.
Inform your doctor if you are taking any medicines. You should tell your doctor if you have glaucoma (increased pressure in the eyes), difficulty in passing urine (water) due to prostate trouble or any other cause. The doctor should also be informed if you had or have convulsions, fits, or seizures, and kidney-related problems. Let your doctor know if you are pregnant, trying to become pregnant or are breastfeeding. Any intolerance to some sugars should be told as well because Pizotifen tablets have lactose, a type of sugar.
Pitofen 0.5mg Tablet should be taken as prescribed by the doctor. This medicine only helps to prevent migraine, it does not treat migraine attack. Do not stop the medicine and take it regularly, even if you feel well.
Yes, Pitofen 0.5mg Tablet can be taken with paracetamol or ibuprofen, as it does not interfere with the working of paracetamol or ibuprofen. Similarly, these medicines do not interfere with the working of pizotifen. However, consult with your doctor before taking any medicine.

Fact Box

Chemical Class

Cycloheptathiophenes

Habit Forming

No

Therapeutic Class

VITAMINS MINERALS NUTRIENTS

Action Class

Serotonin Antagonists- Migraine Prevention

References

  1. Pizotifen [Patient Information Leaflet]. Quebec, Canada: Paladin Labs Inc.; 2023.
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities
<h3 class=titleMediumExtraBold>Want to know more</h3>

Want to know more

We provide you with authentic, trustworthy and relevant information
<h3 class=titleMediumExtraBold>Have issue with the content</h3>

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: New Medicon Pharma Labs Pvt Ltd
Address: T.T.K Road, 1st Floor, Diwan Shahib Garden, Royapettah, Chennai - 600 014.

Vendor Details

Country of origin: India
Why we need a prescription?
Image of Step
Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
Image of Step
In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
close sheet