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Piloxin 500mg Injection

Pefloxacin (500mg)
Genuine
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Piloxin 500mg Injection is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues, and lungs (pneumonia). It cures the infection by stopping further growth of the causative microorganisms.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 11 Aug 2026 | 01:02 AM (IST)
₹225 MRP ₹250.3110% off 
 
 
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Piloxin 500mg Injection image
Piloxin 500mg Injection image

Product introduction

Piloxin 500mg Injection is given as an injection into a vein (intravenous), in cases where oral administration is not possible, such as in hospitalized or unconscious patients. It is administered by a healthcare professional. Do not self-administer. Avoid skipping any doses and finish the full course of treatment even if you feel better.

Some people may have nausea, headache, and dizziness as side effects of this medicine. You may also notice some injection site reactions like pain, swelling, or redness. These are usually temporary and resolve on their own. Consult your doctor if these side effects persist for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.

You should not take this medicine if you are allergic to any of its ingredients. Rarely, some people may have a severe allergic reaction that needs urgent medical attention. Signs of this include rash, swelling of the lips, tongue, or face, shortness of breath, or breathing problems. Special care should be taken in people with kidney or liver problems while taking this medicine.

Uses of Piloxin Injection

Benefits of Piloxin Injection

Bacterial infections
Piloxin 500mg Injection is an antibiotic medicine which can be used to treat many different infections caused by bacteria. These include infections of the ear, nose, throat, lungs, urinary tract, skin, and soft tissues in adults and children. It works by killing and stopping the growth of the bacteria causing the infection.
It is given by a doctor or a nurse and should not be self-administered. This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant.

Side effects of Piloxin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Piloxin
  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
  • Injection site reactions (pain, swelling, redness)

How to use Piloxin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Piloxin Injection works

Piloxin 500mg Injection is an antibiotic. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

Quick tips

  • Your doctor has prescribed Piloxin 500mg Injection to cure your infection and improve symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Discontinue Piloxin 500mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
  • Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Piloxin 500mg Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Piloxin 500mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Piloxin 500mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Piloxin 500mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Piloxin 500mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Piloxin 500mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Piloxin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Pefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Pefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Pefloxacin. Please consult your doctor. Pefloxacin may reduce the efficacy of Cholera Vaccine (Inactivated).
Moderate

Acenocoumarol (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Acenocoumarol accordingly.
Moderate

Warfarin (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly.
Moderate

Aceclofenac (Oral Route)

Do not consume Pefloxacin with Aceclofenac. If concurrent use is essential, watch out for convulsions and seizures and consult your doctor if you experience them. They may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

Yes, the use of Piloxin 500mg Injection can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If you are experiencing severe diarrhea, talk to your doctor about it.
Yes, use of Piloxin 500mg Injection is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take Piloxin 500mg Injection. Inform your doctor if you feel any kind of muscle pain while using this medicine.

Fact Box

Chemical Class

Quinoline carboxylic acids

Habit Forming

No

Therapeutic Class

OPHTHAL OTOLOGICALS

Action Class

Bacterial DNA Replication Inhibitors- Quinolones/ Fluroquinolones
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Apex Laboratories Private Limited
Address: SIDCO Garment Complex, III Floor, Guindy, Chennai-600 032 Tamil Nadu, INDIA

Vendor Details

Country of origin: India
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