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Pefloxacin is used to treat bacterial infections of the gut, ear, nose, throat, lungs, bones, joints, skin, urinary tract, and prostate. It is also used in the treatment of infections that are sexually transmitted.

How it works

Pefloxacin belongs to the class of drugs called as fluroquinolone. It acts by inhibiting the synthesis of proteins which are needed for bacterial replication, thereby arresting its multiplication.

Common side effects

Nausea, Nervousness, Abdominal pain, Allergy, Joint pain, Gastrointestinal discomfort, Headache, Insomnia, Itching, Muscle pain, Vomiting


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Expert advice

  • Always take pefloxacin along with food. 
  • Avoid sun or UV light exposure during pefloxacin therapy as it may cause photosensitivity.
  • Inform your doctor if you are additionally receiving treatment with theophylline, usually for lung diseases, as pefloxacin may cause theophylline toxicity.
  • Tell your doctor if you are pregnant or think you may become pregnant or breastfeeding. 

Content on this page was last updated on 30 September, 2016, by Dr. Varun Gupta (MD Pharmacology)