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Phenil Injection

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 18 Jan 2026 | 06:24 PM (IST)
Phenil Injection is an antihistamine used to treat allergic conditions (such as hay fever, drug rashes, allergic conjunctivitis, food allergy, etc.), respiratory tract conditions, and other skin conditions. It effectively reduces the severity, duration, and occurrence of symptoms and provides quick relief.
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General Information

The content is shown in English
Phenil Injection image
Phenil Injection image

Product introduction

Phenil Injection is also used to treat and prevent motion sickness, symptoms of Meniere’s disease (such as nausea, vomiting, and vertigo), and other associated labyrinthine disturbances.


It is given as an injection into the veins or muscles under the supervision of a doctor. It should be used as per the instruction of your doctor. The dose and how often you take it depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take Phenil Injection for as long as it is prescribed for you.


Sedation is the most common side effect of Phenil Injection. Avoid driving or attention-seeking activities. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. In some cases, it may cause dry mouth, so it is advised to drink more water, always carry sugar candy, or maintain oral hygiene.


Before taking this medicine, let your doctor know if you have glaucoma, asthma, or high blood pressure. Inform your doctor if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment with Phenil Injection.

Uses of Phenil Injection

  • Treatment of Allergic conditions
  • Treatment and prevention of Meniere's disease
  • Treatment of Respiratory disease with excessive mucus
  • Treatment of Skin conditions with inflammation & itching

Benefits of Phenil Injection

Treatment of Allergic conditions
Phenil Injection is widely used in allergic conditions such as hay fever, drug rashes, food allergies, allergic conjunctivitis, angioneurotic oedema, and serum sickness. It works by blocking histamine-mediated allergic responses, thereby reducing symptoms like itching, swelling, redness, sneezing, and watery eyes, and improving overall symptom control during allergic reactions.
Treatment and prevention of Meniere's disease
In Meniere’s disease, Phenil Injection helps manage symptoms such as vertigo, nausea, and vomiting. Its antihistaminic and anti-emetic properties help stabilize inner ear–related symptoms, providing relief from dizziness and associated discomfort.
Treatment of Respiratory disease with excessive mucus
In respiratory conditions such as acute rhinitis and vasomotor rhinitis, where increased nasal secretions are present, Phenil Injection helps relieve symptoms by blocking the effects of histamine. This reduces excessive mucus production, sneezing, and nasal irritation, helping improve breathing comfort and reducing discomfort associated with allergic or irritative respiratory conditions.
Treatment of Skin conditions with inflammation & itching
Phenil Injection is beneficial in itching skin conditions such as eczema, urticaria, neurodermatitis, and other pruritic disorders. It helps reduce itching, redness, and skin irritation, which can improve comfort and prevent further skin damage caused by scratching.

Side effects of Phenil Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Phenil
  • Sedation

How to use Phenil Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Phenil Injection works

Phenil Injection is an antiallergic medication. It works by blocking the action of a chemical messenger (histamine). This relieves symptoms of severe allergic reactions due to insect bite/sting, certain medicines, and hives (such as rashes and swelling).

All substitutes for Phenil Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Inform your doctor if you have any other allergies, including food allergies.
  • Avoid consuming alcohol when taking the Phenil Injection, as it may cause excessive sleepiness or drowsiness.
  • Inform your doctor if you are taking any other medications, e.g., antidepressants.
  • Keep sipping water or have sugar-free gum in order to relieve dryness in the mouth.
  • Avoid stepping outside during peak pollen season and protect yourself from dust and mites at home.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Phenil Injection.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Phenil Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Phenil Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Phenil Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Phenil Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Phenil Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Phenil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Dextromethorphan Hydrobromide (Oral Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.
Moderate

Ketamine (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Tranylcypromine (Oral Route)

Do not take Tranylcypromine with Pheniramine. If concurrent use is essential, talk to your doctor.
Mild

Betahistine (Oral Route)

Take Pheniramine with Betahistine only if prescribed by your doctor. Pheniramine may block the action of Betahistine.

Frequently asked questions

Phenil Injection is an antihistamine used to treat a variety of allergic conditions, including allergic rhinitis, urticaria, skin itching, insect bites, drug and food allergies, and allergic conjunctivitis. It is also used in conditions like Meniere’s disease and other inner-ear disorders to help relieve vertigo, nausea, and vomiting.
It works by blocking the action of histamine, a chemical released during allergic reactions. By preventing histamine from acting on tissues, it helps reduce symptoms such as itching, redness, swelling, sneezing, excessive mucus secretion, dizziness, and nausea.
Yes. Phenil Injection may cause drowsiness, dizziness, or sedation, as it is a first-generation antihistamine. Patients should avoid driving, operating machinery, or performing tasks that require alertness until they know how the medicine affects them.
Phenil Injection should not be used in people who are allergic to pheniramine or similar antihistamines. Caution is advised in patients with glaucoma, enlarged prostate, urinary retention, asthma, or heart disease, and it should be used only under medical supervision in such cases.

Fact Box

Chemical Class

Pheniramines

Habit Forming

No

Therapeutic Class

RESPIRATORY

Action Class

First-Generation H1 Antihistamines

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1100.
  2. Pheniramine Maleate Injection [Prescribing Information]. Sirmour, Himachal Pradesh: Sanofi India Limited; 2021.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Tribhawan Injectables
Address: Plot No-C/11, Sector 4, DSIDC, Industrial complex, Bawana Industrial Area, Narela Zone, Gali No-39, Delhi-110039, India

Vendor Details

Country of origin: India
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