Pericarpine 5mg Tablet

Pilocarpine (5mg)

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Pericarpine 5mg Tablet is used for the treatment of dry mouth after radiotherapy for head and neck cancer. It also helps manage dry mouth in individuals with Sjögren’s syndrome. It works by reducing abnormal dryness of the mouth, which makes speaking and swallowing easier.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Jul 2026 | 01:04 AM (IST)

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General Information

Contains

Pilocarpine (5mg)

Marketer

Pericles Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Pericarpine 5mg Tablet is generally administered by a healthcare professional in the hospital or in a clinical setting. You should not self-administer this medicine at home.

Pericarpine 5mg Tablet may cause a few side effects, such as sweating, frequent urge to urinate, vomiting, nausea, and chills. If you experience such symptoms that persist or worsen, or any other symptoms that you think may be due to Pericarpine 5mg Tablet, inform your doctor.

Before taking Pericarpine 5mg Tablet, inform your doctor if you have any underlying health conditions associated with the heart, lungs, kidneys, or liver. Also, tell your doctor if you are pregnant or breastfeeding.

Uses of Pericarpine Tablet

Dry mouth after radiotherapy of head and neck cancer
Treatment of Sjogren’s Syndrome

Benefits of Pericarpine Tablet

Dry mouth after radiotherapy of head and neck cancer
Radiation therapy to the head, face, or neck may also cause dry mouth. It can take 6 months or longer after radiation therapy ends for the salivary glands to start producing saliva again. Pericarpine 5mg Tablet helps to increase the secretions of body fluids, particularly saliva and this helps to improve dry mouth due to radiation therapy. Take it as prescribed by the doctor to get the most benefit.

Treatment of Sjogren’s Syndrome
Sjögren’s syndrome is an autoimmune disease characterized by dry mouth and dry eyes. Pericarpine 5mg Tablet helps relieve dry mouth in Sjögren’s syndrome by stimulating natural saliva. This improves oral comfort, reduces difficulties in speaking and swallowing, and prevents dental issues caused by dryness. Restoring moisture balance helps improve daily comfort, boosts confidence, and improves overall quality of life for individuals with Sjögren’s syndrome.

Side effects of Pericarpine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pericarpine

Sweating
Frequent urge to urinate
Chills
Vomiting
Nausea

How to use Pericarpine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pericarpine 5mg Tablet may be taken with or without food.

How Pericarpine Tablet works

Pericarpine 5mg Tablet is a cholinergic agonist. It works by stimulating certain nerves and glands in your body, thereby increasing the production of saliva, tears, sweat, digestive juices, and other secretions.

All substitutes for Pericarpine 5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Inform your doctor if you have eye inflammation, suffer from asthma, liver, kidney, or heart diseases, Parkinson’s disease, stomach ulcer, have problems in passing urine, high blood pressure, or narrow-angle glaucoma (increased eyeball pressure due to obstruction to the outflow of fluid).
Drink sufficient water to reduce dehydration due to excessive sweating caused by Pericarpine 5mg Tablet.
The back layer of your eye (fundus) may be examined before starting this medicine.
You may be regularly monitored for visual fields and intraocular pressure on long-term therapy with pilocarpine for glaucoma.
Do not drive or operate machinery as pilocarpine causes dizziness and blurring of vision, especially at night.
Tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Pericarpine 5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pericarpine 5mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Pericarpine 5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Pericarpine 5mg Tablet may cause temporary visual disturbances. Do not drive until your vision is clear.

Kidney

SAFE IF PRESCRIBED

Pericarpine 5mg Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.

Liver

CAUTION

Pericarpine 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Pericarpine 5mg Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Pericarpine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Donepezil (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Rivastigmine (Transdermal Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Rivastigmine may increase the metabolism of Pilocarpine.

Moderate

Rivastigmine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Rivastigmine may increase the metabolism of Pilocarpine.

Moderate

Galantamine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Pilocarpine may increase the effect of Galantamine.

Frequently asked questions

What is Pericarpine 5mg Tablet used for?

Pericarpine 5mg Tablet is used to treat dry mouth in radiation treatment for head and neck cancer, and in Sjögren’s syndrome (an autoimmune condition manifesting dry mouth). It helps stimulate and increase saliva production in the mouth providing relief from dryness.

When should I avoid taking Pericarpine 5mg Tablet?

You should avoid taking Pericarpine 5mg Tablet if you have uncontrolled asthma, are allergic to pilocarpine (active medicine in Pericarpine 5mg Tablet), and have certain eye problems like narrow-angle glaucoma or inflammation of the iris (iritis).

What should I tell my doctor before taking Pericarpine 5mg Tablet?

Before taking Pericarpine 5mg Tablet, let your doctor know if you have heart problems, lung diseases like asthma or COPD, liver issues, gallbladder or urinary problems, are pregnant or breastfeeding, and/or taking other medicines, especially for heart, breathing, or mental health.

What are the serious side effects of Pericarpine 5mg Tablet during Pericarpine 5mg Tablet treatment?

You should call your doctor right away if you have experienced serious side effects of Pericarpine 5mg Tablet such as trouble breathing, wheezing, or a tight chest, fast or irregular heartbeat, severe stomach pain or vomiting, severe dizziness or fainting, and/or blurry vision, especially at night.

Can I drink alcohol while taking Pericarpine 5mg Tablet?

It is advisable to limit alcohol consumption while taking Pericarpine 5mg Tablet, as alcohol can increase the risk of certain side effects, such as dizziness and drowsiness.

How long does it take for Pericarpine 5mg Tablet to work?

The exact time Pericarpine 5mg Tablet takes to show its effect is not known. However, you may start noticing improvement in the symptoms within a week while the full benefit may take several weeks of continuous use. Be patient and follow your doctor's instructions regarding the duration of treatment.

Is Pericarpine 5mg Tablet safe during pregnancy and breastfeeding?

The safety of Pericarpine 5mg Tablet during pregnancy and breastfeeding has not been well established. Consult your doctor before using Pericarpine 5mg Tablet if you are pregnant, planning to become pregnant, or breastfeeding.

Fact Box

Chemical Class

Alkaloid derivative

Habit Forming

Therapeutic Class

OPHTHAL

Action Class

Cholinomimetic Alkaloids- Pilocarpine

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1120-21.
Pilocarpine hydrochloride [Product Information]. Columbus, OH: American Health Packaging; 2025. [Accessed 03 Apr. 2025] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Pericles Pharma
Address: B-702 Aaryan Euphoria, opp. Kargil petrol pump, Gujarat 380061

Vendor Details

Country of origin: India

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Pericarpine 5mg Tablet

Pericarpine 5mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pericarpine Tablet

Benefits of Pericarpine Tablet

Side effects of Pericarpine Tablet

How to use Pericarpine Tablet

How Pericarpine Tablet works

All substitutes for Pericarpine 5mg Tablet

Pilomax Tablet

Jogren 5mg Tablet

Jogren Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Donepezil (Oral Route)

Rivastigmine (Transdermal Route)

Rivastigmine (Oral Route)

Galantamine (Oral Route)

Frequently asked questions

What is Pericarpine 5mg Tablet used for?

When should I avoid taking Pericarpine 5mg Tablet?

What should I tell my doctor before taking Pericarpine 5mg Tablet?

What are the serious side effects of Pericarpine 5mg Tablet during Pericarpine 5mg Tablet treatment?

Can I drink alcohol while taking Pericarpine 5mg Tablet?

How long does it take for Pericarpine 5mg Tablet to work?

Is Pericarpine 5mg Tablet safe during pregnancy and breastfeeding?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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