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Jogren Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 18 Mar 2026 | 02:05 PM (IST)
Jogren Tablet is used for the treatment of dry mouth after radiotherapy for head and neck cancer. It also helps manage dry mouth in individuals with Sjögren’s syndrome. It works by reducing abnormal dryness of the mouth, which makes speaking and swallowing easier.
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Available in pack-size of 10 tablets
10 tablets pack-size available
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General Information

The content is shown in English
Jogren Tablet image
Jogren Tablet image
Jogren Tablet image
Jogren Tablet image

Product introduction

Jogren Tablet is generally administered by a healthcare professional in the hospital or in a clinical setting. You should not self-administer this medicine at home.


Jogren Tablet may cause a few side effects, such as sweating, frequent urge to urinate, vomiting, nausea, and chills. If you experience such symptoms that persist or worsen, or any other symptoms that you think may be due to Jogren Tablet, inform your doctor.


Before taking Jogren Tablet, inform your doctor if you have any underlying health conditions associated with the heart, lungs, kidneys, or liver. Also, tell your doctor if you are pregnant or breastfeeding.

Uses of Jogren Tablet

Benefits of Jogren Tablet

Dry mouth after radiotherapy of head and neck cancer
Radiation therapy to the head, face, or neck may also cause dry mouth. It can take 6 months or longer after radiation therapy ends for the salivary glands to start producing saliva again. Jogren Tablet helps to increase the secretions of body fluids, particularly saliva and this helps to improve dry mouth due to radiation therapy. Take it as prescribed by the doctor to get the most benefit.
Treatment of Sjogren’s Syndrome
Sjögren’s syndrome is an autoimmune disease characterized by dry mouth and dry eyes. Jogren Tablet helps relieve dry mouth in Sjögren’s syndrome by stimulating natural saliva. This improves oral comfort, reduces difficulties in speaking and swallowing, and prevents dental issues caused by dryness. Restoring moisture balance helps improve daily comfort, boosts confidence, and improves overall quality of life for individuals with Sjögren’s syndrome.

Side effects of Jogren Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Jogren
  • Sweating
  • Frequent urge to urinate
  • Chills
  • Vomiting
  • Nausea

How to use Jogren Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jogren Tablet may be taken with or without food.

How Jogren Tablet works

Jogren Tablet is a cholinergic agonist. It works by stimulating certain nerves and glands in your body, thereby increasing the production of saliva, tears, sweat, digestive juices, and other secretions.

All substitutes for Jogren Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Inform your doctor if you have eye inflammation, suffer from asthma, liver, kidney, or heart diseases, Parkinson’s disease, stomach ulcer, have problems in passing urine, high blood pressure, or narrow-angle glaucoma (increased eyeball pressure due to obstruction to the outflow of fluid).
  • Drink sufficient water to reduce dehydration due to excessive sweating caused by Jogren Tablet.
  • The back layer of your eye (fundus) may be examined before starting this medicine.
  • You may be regularly monitored for visual fields and intraocular pressure on long-term therapy with pilocarpine for glaucoma.
  • Do not drive or operate machinery as pilocarpine causes dizziness and blurring of vision, especially at night.
  • Tell your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Jogren Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Jogren Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Jogren Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Jogren Tablet may cause temporary visual disturbances. Do not drive until your vision is clear.
Kidney

Kidney

SAFE IF PRESCRIBED
Jogren Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CAUTION
Jogren Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Jogren Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Jogren with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Donepezil (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Galantamine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Pilocarpine may increase the effect of Galantamine.
Moderate

Rivastigmine (Transdermal Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate

Rivastigmine (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

Jogren Tablet is used to treat dry mouth in radiation treatment for head and neck cancer, and in Sjögren’s syndrome (an autoimmune condition manifesting dry mouth). It helps stimulate and increase saliva production in the mouth providing relief from dryness.
You should avoid taking Jogren Tablet if you have uncontrolled asthma, are allergic to pilocarpine (active medicine in Jogren Tablet), and have certain eye problems like narrow-angle glaucoma or inflammation of the iris (iritis).
Before taking Jogren Tablet, let your doctor know if you have heart problems, lung diseases like asthma or COPD, liver issues, gallbladder or urinary problems, are pregnant or breastfeeding, and/or taking other medicines, especially for heart, breathing, or mental health.
You should call your doctor right away if you have experienced serious side effects of Jogren Tablet such as trouble breathing, wheezing, or a tight chest, fast or irregular heartbeat, severe stomach pain or vomiting, severe dizziness or fainting, and/or blurry vision, especially at night.
It is advisable to limit alcohol consumption while taking Jogren Tablet, as alcohol can increase the risk of certain side effects, such as dizziness and drowsiness.
The exact time Jogren Tablet takes to show its effect is not known. However, you may start noticing improvement in the symptoms within a week while the full benefit may take several weeks of continuous use. Be patient and follow your doctor's instructions regarding the duration of treatment.
The safety of Jogren Tablet during pregnancy and breastfeeding has not been well established. Consult your doctor before using Jogren Tablet if you are pregnant, planning to become pregnant, or breastfeeding.

Fact Box

Chemical Class

Alkaloid derivative

Habit Forming

No

Therapeutic Class

OPHTHAL

Action Class

Cholinomimetic Alkaloids- Pilocarpine

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1120-21.
  2. Pilocarpine hydrochloride [Product Information]. Columbus, OH: American Health Packaging; 2025. [Accessed 03 Apr. 2025] (online) Available from:
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hetero Healthcare Limited
Address: S.no: 80-84, Melange towers, PatrikaNagar,Madhapur,Hyderabad. Telangana-500081.

Vendor Details

Country of origin: India
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