


Pcl Syrup
Cyproheptadine (NA)
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Pcl Syrup belongs to a group of medicines called antihistamines. It is used in the treatment of various allergic conditions. It relieves symptoms of inflammation as well as itching, swelling and rashes. It is also used to treat loss of appetite (need for food). It is an effective hunger stimulant.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Jan 2026 | 11:25 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Jan 2026 | 11:25 AM (IST)
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General Information
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Product introduction
Pcl Syrup can be taken with or without food and it is better to take it in a dose and duration as advised by the doctor. You may need this medicine only on days you have symptoms, or you may need to take it every day to prevent symptoms from happening. If you stop taking it earlier than advised, your symptoms may come back. This medicine is generally very safe.
Pcl Syrup may cause some amount of dizziness, so do not drive or do anything that needs attention. Consult your doctor if it persists or worries you. It may cause a headache in some cases. Before taking it, you should tell your doctor if you have any problems with your liver or kidneys or with your heart. Avoid drinking alcohol as it can cause excessive drowsiness with this medicine.
Uses of Pcl Syrup
Benefits of Pcl Syrup
Treatment of Allergic conditions
Pcl Syrup prevents the release of substances in the body that cause inflammation and symptoms such as blocked or runny nose, sneezing, and itchy or watery eyes. It can be used to treat a great many different inflammatory and allergic conditions. It lowers your immune system’s response to these conditions so you should avoid being near people who are ill or have infections.
Pcl Syrup prevents the release of substances in the body that cause inflammation and symptoms such as blocked or runny nose, sneezing, and itchy or watery eyes. It can be used to treat a great many different inflammatory and allergic conditions. It lowers your immune system’s response to these conditions so you should avoid being near people who are ill or have infections.
Appetite stimulant
Pcl Syrup increases hunger by constantly increasing the energy requirements of an individual. It promotes the desire to eat and therefore, it is a safe and effective way of managing undernutrition or malnutrition. It helps to treat loss of appetite and improves the nutritional status.
Pcl Syrup increases hunger by constantly increasing the energy requirements of an individual. It promotes the desire to eat and therefore, it is a safe and effective way of managing undernutrition or malnutrition. It helps to treat loss of appetite and improves the nutritional status.
Side effects of Pcl Syrup
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pcl
- Impaired coordination
- Dizziness
- Headache
- Sleepiness
How to use Pcl Syrup
Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Pcl Syrup may be taken with or without food.
How Pcl Syrup works
Pcl Syrup is an antihistamine medication. It blocks the action of certain chemical messengers that are responsible for inflammation, congestion, itching, and other allergic reactions. Due to constant increased energy intake and stimulation of growth hormone secretion, it stimulates the appetite too.
All substitutes for Pcl Syrup
For information purposes only. Consult a doctor before taking any medicine.
Quick tips
- Take Pcl Syrup as per dose and duration suggested by your doctor.
- Avoid driving or operating dangerous machinery as it may decrease alertness.
- Avoid consuming alcohol when taking the Pcl Syrup, as it may cause excessive sleepiness or drowsiness.
Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Pcl Syrup.

Pregnancy
SAFE IF PRESCRIBED
Pcl Syrup is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding
CAUTION
Pcl Syrup should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving
UNSAFE
Pcl Syrup may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney
CAUTION
Pcl Syrup should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Pcl Syrup should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs
Taking Pcl with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate
Clozapine (Oral Route)
Watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, loss of appetite or nausea and consult your doctor if you experience them.
Moderate
Thalidomide (Oral Route)
If concurrent use is essential, watch out for symptoms of Thalidomide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Moderate
Ketamine (Injection Route)
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.
Moderate
Vilazodone (Oral Route)
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Cyproheptadine may reduce the efficacy of Vilazodone.
Moderate
Sertraline (Oral Route)
If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Cyproheptadine may reduce the efficacy of Sertraline.
Frequently asked questions
Pcl Syrup is mainly used to treat allergy symptoms, such as sneezing, a runny nose, itchy eyes, and hives. It can also help with skin reactions like urticaria, and it is sometimes used to support appetite by stimulating hunger.
Pcl Syrup should not be given to children under 2 years old, as it can cause serious side effects. In children aged 2 years and above, it may be used cautiously but only under a doctor's supervision, due to the risk of excitability or drowsiness.
No, Pcl Syrup is not recommended for people with glaucoma (angle-closure), enlarged prostate, or bladder issues, as it may worsen these conditions. Always tell your doctor about existing health problems before using Pcl Syrup.
Yes, Pcl Syrup causes drowsiness in many people, especially during the first few days of use. You should avoid driving or operating machinery until you know how the medication affects you.
Pcl Syrup is not addictive or habit-forming, but it should be taken exactly as prescribed. Do not increase the dose or frequency without your doctor's advice.
People with severe liver disease, urinary retention, stomach ulcers, or who are currently using MAO inhibitors (a type of antidepressant) should not use Pcl Syrup. It is also not suitable for the elderly with cognitive decline, due to increased risk of confusion.
Yes, Pcl Syrup is sometimes used to stimulate appetite, especially in people who are underweight or have conditions causing loss of appetite. However, this should only be done under medical supervision to avoid unwanted side effects.
Fact Box
Chemical Class
Dibenzocycloheptenes
Habit Forming
No
Therapeutic Class
RESPIRATORY
Action Class
First-Generation H1 Antihistamines
Related lab tests
References
- Katzung BG. Histamines, Serotonin, & the ErgotAlkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285.
- Sanders-Bush E, Hazelwood L. 5-Hydroxytryptamine (Serotonin) and Dopamine. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 351.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 342-43.
- Cyproheptadine. Hinjwadi, Pune: Emcure Pharmaceuticals Ltd.; 2017 [Accessed 1 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
- Cyproheptadine HCI [Drug Label]. Pune, India: Emcure Pharmaceuticals Ltd.; 2009. [Accessed 25 Jul. 2024] (online) Available from:
- Cyproheptadine HCI [Drug Label]. Pulaski, TN: AvKARE; 2024. [Accessed 19 Jan. 2026] (online). Available from:
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User feedback
Once A Day
53%
Twice A Day
47%
Appetite stimulant
100%
Average
100%
Sleepiness
100%
With or without food
100%
Average
100%
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
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- Serum Electrolytes
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- Cholesterol - Total
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