Palbopro 125mg Capsule is used to treat patients with certain types of breast cancer (estrogen receptor-positive, human epidermal growth factor receptor 2-negative) which have spread to other organs. It is given together with hormonal anticancer therapies.
Palbopro 125mg Capsule is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your need and response to treatment. You may be asked for regular blood tests while taking this medication. It is better to inform doctor if you notice symptoms of infection like fever, chills and weakness. You should use effective contraception method to prevent pregnancy while taking this medicine
It may cause dizziness, so avoid driving or any activity requiring mental focus until you know how it affects you. Most of the side effects of Palbopro 125mg Capsule is reversible and disappear when the medicine is stopped. Neutropenia is a well-recognized adverse effect, in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection. However, this side effect disappears rapidly once you stop taking the medicine.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Palbopro
Fatigue
Hair loss
Rash
Vomiting
Diarrhea
Nausea
Decreased appetite
Infection
Stomatitis (Inflammation of the mouth)
Anemia (low number of red blood cells)
Weakness
Fever
Decreased white blood cell count
How to use Palbopro Capsule
Take this medicine in the dose and duration as advised by your doctor. Palbopro 125mg Capsule is to be taken with food.
How Palbopro Capsule works
Palbopro 125mg Capsule is an anti-cancer medication. Cyclin dependent kinase 4 and 6
(chemical messengers) are downstream of signaling pathways which lead to the proliferation of cells. This medicine works by inhibiting cyclin dependent kinase 4 and 6, thus arrests the cancer cell cycle (cell growing process). It also targets the estrogen (hormone) receptor-positive breast cancer cells by disrupting the cell cycle.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Palbopro 125mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Palbopro 125mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Palbopro 125mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Palbopro 125mg Capsule may cause side effects which could affect your ability to drive. It may cause fatigue in some people. If this happens, you should exercise caution when driving or using machines.
Kidney
SAFE IF PRESCRIBED
Palbopro 125mg Capsule is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Palbopro 125mg Capsule may not be needed in these patients. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Palbopro 125mg Capsule in patients with liver disease. Please consult your doctor. The dose should be adjusted in mild liver impairment
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Take it with food, preferably at the same time every day.
If you forget to take the medicine or vomit, skip the missed dose and follow a regular schedule. Do not take a double dose to make up missed dose
Use effective contraception method to prevent pregnancy while taking this medicine.
It may cause dizziness. Avoid driving or any activity requiring mental focus until you know how it affects you.
You may be asked for regular blood tests while taking this medication. Inform your doctor if you notice symptoms of infection like fever, chills, and weakness.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Do not stop taking the medication without talking to your doctor first.
Fact Box
Chemical Class
Pyridinylpiperazines
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Cyclin-Dependent Kinase Inhibitor
Patient concerns
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
I am PATIENT have pain in my breastes and feel very weight before one week of my menstrual perieds date Is it any symptoms of breast cancer ? Need your advice And also having back pain during menstrual dates please give your valubel advice
Dear PATIENT 4 Breast Cancer means that the cancer has spread to other parts of the body. The management of such cancers depends on the site where the cancer has spread and on the receptor status of the breast cancer. If you can share the details with me, I will be happy to let you know the potential management
Palbopro 125mg Capsule is an anti-cancer medicine. Palbopro 125mg Capsule blocks proteins known as cyclin-dependent kinase inhibitors. Blocking these proteins can slow down the growth of cancer cells and delay the progression of the cancer.
How long do I have to take Palbopro 125mg Capsule?
The duration of treatment varies from person to person. Your doctor will decide the number of cycles you need to receive based on your condition, response to treatment and your tolerance to side effects. Your doctor may decrease your dose or stop your treatment temporarily or permanently if you experience certain side effects.
Are the side effects of Palbopro 125mg Capsule irreversible?
No, most of the side effects are reversible and disappear when the medicine is stopped. Neutropenia is a well-recognized adverse effect of Palbopro 125mg Capsule in which the number of your white blood cells get reduced and your immune system gets weakened. As a result, you may be at greater risk of getting an infection while you are taking Palbopro 125mg Capsule. However, this side effect disappears rapidly once you stop taking the medicine.
Does treatment with Palbopro 125mg Capsule require monitoring of blood counts?
Yes, blood tests are important since this medicine can lower your blood counts. The regular blood tests check the effect of Palbopro 125mg Capsule on your blood cells (white blood cells, red blood cells, and platelets). These tests should be done at the beginning of each chemotherapy cycle, on the 15th day of the first 2 cycles, and as clinically indicated.
How should I take Palbopro 125mg Capsule?
Generally, Palbopro 125mg Capsule is taken once daily for 21 consecutive days followed by 7 days off treatment to add up a complete cycle of 28 days. Take this medicine with food and at the same time each day. Swallow the whole capsules. Do not open, chew, or crush them. Do not take the capsules that are broken or cracked. If you vomit after taking Palbopro 125mg Capsule, do not take another dose and continue your regular dosing schedule.
Do I need to use birth control method while using Palbopro 125mg Capsule?
Women of childbearing potential who are receiving Palbopro 125mg Capsule and their partners should use adequate contraceptive methods (e.g. double-barrier contraception such as condom and diaphragm). These methods should be used during therapy and for at least 3 weeks after completing therapy for females. Men who are on Palbopro 125mg Capsule therapy should use birth control methods for at least 14 weeks after completing the therapy.
Does Palbopro 125mg Capsule affect fertility?
Male fertility may be affected during treatment with Palbopro 125mg Capsule. Thus, men may consider sperm preservation prior to beginning therapy with Palbopro 125mg Capsule.
What are the serious side effects of Palbopro 125mg Capsule?
The serious side effects of Palbopro 125mg Capsule include shortness of breath, dizziness, weakness, unusual bleeding or bruising or nosebleeds. It may also cause fever, chills or signs of infection and fast, irregular or pounding heartbeat. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment.
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References
Palbociclib. New York, New York: Pfizer Labs; 2015 [revised 31 Mar. 2017]. [Accessed 25 Jun. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: RPG Life Sciences Ltd
Address: 463, 4 th Floor, RPG HOUSE, Dr. Annie Besant Road, Worli, Mumbai – 400 030. Maharashtra, INDIA