Pakvil 22.75mg Injection

Pheniramine (22.75mg/ml)

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Pakvil 22.75mg Injection is an antihistamine used to treat allergic conditions (such as hay fever, drug rashes, allergic conjunctivitis, food allergy, etc.), respiratory tract conditions, and other skin conditions. It effectively reduces the severity, duration, and occurrence of symptoms and provides quick relief.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 29 Apr 2026 | 01:02 PM (IST)

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Pakvil 22.75mg Injection

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AVil Injection

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Pheniramine (22.75mg/ml)

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General Information

Contains

Pheniramine (22.75mg/ml)

Marketer

Paksons Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Pakvil 22.75mg Injection is also used to treat and prevent motion sickness, symptoms of Meniere’s disease (such as nausea, vomiting, and vertigo), and other associated labyrinthine disturbances.

It is given as an injection into the veins or muscles under the supervision of a doctor. It should be used as per the instruction of your doctor. The dose and how often you take it depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take Pakvil 22.75mg Injection for as long as it is prescribed for you.

Sedation is the most common side effect of Pakvil 22.75mg Injection. Avoid driving or attention-seeking activities. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. In some cases, it may cause dry mouth, so it is advised to drink more water, always carry sugar candy, or maintain oral hygiene.

Before taking this medicine, let your doctor know if you have glaucoma, asthma, or high blood pressure. Inform your doctor if you are pregnant or breastfeeding. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Generally, it is advised to avoid alcohol while on treatment with Pakvil 22.75mg Injection.

Uses of Pakvil Injection

Treatment of Allergic conditions
Treatment and prevention of Meniere's disease
Treatment of Respiratory disease with excessive mucus
Treatment of Skin conditions with inflammation & itching

Benefits of Pakvil Injection

Treatment of Allergic conditions
Pakvil 22.75mg Injection is widely used in allergic conditions such as hay fever, drug rashes, food allergies, allergic conjunctivitis, angioneurotic oedema, and serum sickness. It works by blocking histamine-mediated allergic responses, thereby reducing symptoms like itching, swelling, redness, sneezing, and watery eyes, and improving overall symptom control during allergic reactions.

Treatment and prevention of Meniere's disease
In Meniere’s disease, Pakvil 22.75mg Injection helps manage symptoms such as vertigo, nausea, and vomiting. Its antihistaminic and anti-emetic properties help stabilize inner ear–related symptoms, providing relief from dizziness and associated discomfort.

Treatment of Respiratory disease with excessive mucus
In respiratory conditions such as acute rhinitis and vasomotor rhinitis, where increased nasal secretions are present, Pakvil 22.75mg Injection helps relieve symptoms by blocking the effects of histamine. This reduces excessive mucus production, sneezing, and nasal irritation, helping improve breathing comfort and reducing discomfort associated with allergic or irritative respiratory conditions.

Treatment of Skin conditions with inflammation & itching
Pakvil 22.75mg Injection is beneficial in itching skin conditions such as eczema, urticaria, neurodermatitis, and other pruritic disorders. It helps reduce itching, redness, and skin irritation, which can improve comfort and prevent further skin damage caused by scratching.

Side effects of Pakvil Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pakvil

Sedation

How to use Pakvil Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Pakvil Injection works

Pakvil 22.75mg Injection is an antiallergic medication. It works by blocking the action of a chemical messenger (histamine). This relieves symptoms of severe allergic reactions due to insect bite/sting, certain medicines, and hives (such as rashes and swelling).

All substitutes for Pakvil 22.75mg Injection

For information purposes only. Consult a doctor before taking any medicine.

AVil Injection

by Sanofi India Ltd

₹22.01/injection

96% costlier

AVil Injection

by Sanofi India Ltd

₹5.86/injection

48% cheaper

Quick tips

Inform your doctor if you have any other allergies, including food allergies.
Avoid consuming alcohol when taking the Pakvil 22.75mg Injection, as it may cause excessive sleepiness or drowsiness.
Inform your doctor if you are taking any other medications, e.g., antidepressants.
Keep sipping water or have sugar-free gum in order to relieve dryness in the mouth.
Avoid stepping outside during peak pollen season and protect yourself from dust and mites at home.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Pakvil 22.75mg Injection.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Pakvil 22.75mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Pakvil 22.75mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

UNSAFE

Pakvil 22.75mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Pakvil 22.75mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Pakvil 22.75mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Pakvil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Dextromethorphan Hydrobromide (Oral Route)

Do not drive or do anything requiring concentration or alertness until you know how the medicines affect you.

Moderate

Ketamine (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Tranylcypromine (Oral Route)

Do not take Tranylcypromine with Pheniramine. If concurrent use is essential, talk to your doctor.

Mild

Betahistine (Oral Route)

Take Pheniramine with Betahistine only if prescribed by your doctor. Pheniramine may block the action of Betahistine.

Frequently asked questions

What is Pakvil 22.75mg Injection used for?

Pakvil 22.75mg Injection is an antihistamine used to treat a variety of allergic conditions, including allergic rhinitis, urticaria, skin itching, insect bites, drug and food allergies, and allergic conjunctivitis. It is also used in conditions like Meniere’s disease and other inner-ear disorders to help relieve vertigo, nausea, and vomiting.

How does Pakvil 22.75mg Injection work?

It works by blocking the action of histamine, a chemical released during allergic reactions. By preventing histamine from acting on tissues, it helps reduce symptoms such as itching, redness, swelling, sneezing, excessive mucus secretion, dizziness, and nausea.

Can Pakvil 22.75mg Injection cause drowsiness?

Yes. Pakvil 22.75mg Injection may cause drowsiness, dizziness, or sedation, as it is a first-generation antihistamine. Patients should avoid driving, operating machinery, or performing tasks that require alertness until they know how the medicine affects them.

Who should not use Pakvil 22.75mg Injection?

Pakvil 22.75mg Injection should not be used in people who are allergic to pheniramine or similar antihistamines. Caution is advised in patients with glaucoma, enlarged prostate, urinary retention, asthma, or heart disease, and it should be used only under medical supervision in such cases.

Fact Box

Chemical Class

Pheniramines

Habit Forming

Therapeutic Class

RESPIRATORY

Action Class

First-Generation H1 Antihistamines

Related lab tests

Absolute Eosinophil Count

Peripheral Smear Examination

Total IgE

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1100.
Pheniramine Maleate Injection [Prescribing Information]. Sirmour, Himachal Pradesh: Sanofi India Limited; 2021.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Paksons Pharmaceuticals Pvt Ltd
Address: 2/215 Maharaja Aggarsain Commercial Complex Sector 9 Rohini Delhi, Delhi, India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Pakvil 22.75mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Pakvil Injection

Benefits of Pakvil Injection

Side effects of Pakvil Injection

How to use Pakvil Injection

How Pakvil Injection works

All substitutes for Pakvil 22.75mg Injection

AVil Injection

AVil Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Dextromethorphan Hydrobromide (Oral Route)

Ketamine (Injection Route)

Tranylcypromine (Oral Route)

Betahistine (Oral Route)

Frequently asked questions

What is Pakvil 22.75mg Injection used for?

How does Pakvil 22.75mg Injection work?

Can Pakvil 22.75mg Injection cause drowsiness?

Who should not use Pakvil 22.75mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Absolute Eosinophil Count

Peripheral Smear Examination

Total IgE

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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