


Paincure Injection
Tramadol (NA)
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Paincure Injection is a pain-relieving medicine. It is used to manage persistent, moderate to severe chronic pain that requires continuous, around-the-clock treatment.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Sep 2025 | 03:31 PM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 19 Sep 2025 | 03:31 PM (IST)
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General Information
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Product introduction
Paincure Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include nausea, constipation, dry mouth, sleepiness, dizziness, and vomiting. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
The most common side effects of this medicine include nausea, constipation, dry mouth, sleepiness, dizziness, and vomiting. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses of Paincure Injection
- Moderate to severe pain
Benefits of Paincure Injection
Moderate to severe pain
Paincure Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Paincure Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Paincure Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Paincure
- Nausea
- Constipation
- Sleepiness
- Dizziness
- Vomiting
How to use Paincure Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Paincure Injection works
Paincure Injection is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.
Quick tips
- Use only for severe acute pain for not more than 5 days.
- Prolonged use may result in physical and psychological dependence even at recommended dosages.
- Avoid driving or using machinery if you feel dizzy after taking Paincure Injection.
- It is better to take with food to avoid an upset stomach.
- Your doctor may adjust your dose if you have liver or kidney disease.
Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Paincure Injection.

Pregnancy
CONSULT YOUR DOCTOR
Paincure Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
SAFE IF PRESCRIBED
Paincure Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.

Driving
UNSAFE
Paincure Injection may cause side effects which could affect your ability to drive.
Paincure Injection may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Paincure Injection may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.

Kidney
CAUTION
Paincure Injection should be used with caution in patients with kidney disease. Dose adjustment of Paincure Injection may be needed. Please consult your doctor.

Liver
CAUTION
Paincure Injection should be used with caution in patients with liver disease. Dose adjustment of Paincure Injection may be needed. Please consult your doctor.
Interaction with drugs
Taking Paincure with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening
Selegiline (Oral Route)
Do not consume Selegiline with Tramadol. If essential, watch out for symptoms such as fever, tremors, diarrhea or agitation. Please consult your doctor.
Life-threatening
Naltrexone (Oral Route)
Do not consume Naltrexone with Tramadol; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Tramadol.
Life-threatening
Tranylcypromine (Oral Route)
Do not consume Tranylcypromine with Tramadol. If Tranylcypromine is essential, ensure a gap of At least 2 weeks between taking Tranylcypromine and Tramadol. Please consult your doctor.
Severe
Alprazolam (Oral Route)
If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe
Alprazolam (Injection Route)
If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Frequently asked questions
Paincure Injection may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.
Fact Box
Chemical Class
Anisole Derivative
Habit Forming
Yes
Therapeutic Class
PAIN ANALGESICS
Action Class
Opioids
References
- Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 547.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1384-86.
- ScienceDirect. Tramadol. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Cure Quick Pharmaceuticals
Address: Sector 3, Karnal, Haryana 132001
Address: Sector 3, Karnal, Haryana 132001
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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