Paclieva Injection
Prescription Required
Product introduction
Paclieva Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer and non-small cell lung cancer.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Some common side effects of this medicine include nausea, vomiting, and weakness. It may also cause serious side effects such as swelling of hands, lips, hair loss, and weight gain. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function.
Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Paclieva Injection
Benefits of Paclieva Injection
In Breast cancer
Paclieva Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Paclieva Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.
In Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Paclieva Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
In Pancreatic cancer
Pancreas are very essential for digestion of whatever you eat and also for metabolism of blood sugar levels as they produce the body’s natural insulin. This medicine will help to control pancreatic cancer, and will relieve the symptoms such as, lack of appetite or unexplained weight loss. Paclieva Injection helps to stop the action of those chemicals that aid in pancreatic cancer growth and spread. It will help you live a longer and healthier life.
Side effects of Paclieva Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Paclieva
- Nausea
- Vomiting
- Weakness
- Low blood platelets
- Rash
- Upper respiratory tract infection
- Urinary tract infection
- Bleeding
- Anemia (low number of red blood cells)
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Hair loss
- Decreased blood pressure
- Peripheral neuropathy (tingling and numbness of feet and hand)
- Diarrhea
- Decreased white blood cell count (neutrophils)
How to use Paclieva Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Paclieva Injection works
Paclieva Injection is an anticancer medication. It works by interfering with the microtubule structures which help the cancer cells to divide and multiply. This slows the growth of cancer cells and eventually kills them.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Paclieva Injection.
Pregnancy
CONSULT YOUR DOCTOR
Paclieva Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
UNSAFE
Paclieva Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Paclieva Injection may cause side effects which could affect your ability to drive.
As there is no reason why you cannot continue driving between courses of Paclieva Injection but you should remember that this medicine contains some alcohol and it may be unwise to drive
As there is no reason why you cannot continue driving between courses of Paclieva Injection but you should remember that this medicine contains some alcohol and it may be unwise to drive
Kidney
SAFE IF PRESCRIBED
Paclieva Injection is safe to use in patients with kidney disease. No dose adjustment of Paclieva Injection is recommended.
However, talk to your doctor if you have any underlying kidney disease.
However, talk to your doctor if you have any underlying kidney disease.
Liver
CAUTION
Paclieva Injection should be used with caution in patients with liver disease. Dose adjustment of Paclieva Injection may be needed. Please consult your doctor.
Use of Paclieva Injection is not recommended in patients with severe liver disease.
Use of Paclieva Injection is not recommended in patients with severe liver disease.
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Quick tips
- Paclieva Injection is an anti-cancer medication used for the treatment of breast cancer, pancreatic cancer, and non-small cell lung cancer.
- It is given as an intravenous (IV) injection into your vein, usually over 1 hour and every three weeks.
- Do not take Paclieva Injection if you are pregnant or breastfeeding. Use reliable methods of contraception to prevent pregnancy while taking this medicine.
- Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.
- Inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever) or other signs of infection.
- Talk to your doctor if you have sudden weight gain or if you have swelling in your arms and legs that doesn't go away.
Fact Box
Chemical Class
Taxanes Derivatives
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Antimicrotubule agents- Taxanes
Interaction with drugs
Taking Paclieva with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytot
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Paclitaxel from 1 day before until 1 day after taking Molgramostim. Pl
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Paclitaxel from 14 days before until 24 days after taking Pegfilgrasti
Concurrent use may cause a decrease in the ability of the bone marrow to produce blood cells.
Do not consume Paclitaxel from 1 day before until 1 day after taking Sargramostim. Pl
Concomitant use may increase the risk of opportunistic infections.
Do not consume Natalizumab with Paclitaxel.
Patient concerns
FAQs
Is Paclieva Injection generic/ taxane/ FDA approved/cytotoxic?
Yes, Paclieva Injection is generic/ taxane/ FDA approved/ cytotoxic
Is Paclieva Injection a vesicant?
Paclieva Injection is usually a vesicant (irritant)
Is Paclieva Injection light sensitive/ hydrophobic/ cardiotoxic?
Yes, Paclieva Injection is light sensitive/ hydrophobic/ cardiotoxic
Does Paclieva Injection cause hair loss?
Yes, Paclieva Injection may cause hair loss as a side effect. Please inform your doctor about any side effect while you are on Paclieva Injection therapy
What is Paclieva Injection derived from?
Paclieva Injection is derived from bark of the Pacific yew, Taxus brevifolia.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1707-709.
- Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 949.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1044-46.
- Paclitaxel. Hurley, Maidenhead: Hospira UK Ltd.; 2005 [revised Dec. 2016]. [Accessed 24 Jan. 2019] (online) Available from:
- Paclitaxel. Summit, New Jersey: Celgene Corporation; 2005 [revised Oct. 2012]. [Accessed 26 Mar. 2019] (online) Available from:
- Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Paclitaxel. [Updated 2020 Jan 20]. [Accessed 18 Feb. 2020] (online) Available from:
Marketer details
Name: Allieva Pharma
Address: 14/16/1, GROUND FLOOR, SAHIBABAD INDUSTRIAL AREA, GHAZIABAD, U.P.-201010
Country of origin: India
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