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Osteo One Injection

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Osteo One Injection is a medicine used for treatment of pain due to osteoarthritis. This medicine is commonly given when when a patient does not respond to other conventional treatments. It reduces the friction in the joints and decreases the pain and swelling.
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1/2
6 ml Injection
 
 
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General Information

Contains

Sodium Hyaluronate (8mg/ml)

Marketer

Biorange Biologicals Private Limited

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Osteo One Injection image
Osteo One Injection image
Osteo One Injection image

Product introduction

Osteo One Injection is administered by intra‐articular injection. Intra‐articular injection is given by inserting a needle into the space in the knee joint that contains fluid used for lubrication and cushioning. it should not be self-administered as it can be only administered by a qualified doctor. While on treatment with this medicine, you should avoid activities such as strenuous sports and exercise, or standing on your feet for a long time.

Some common side effects of this medicine include injection site reactions (such as pain, swelling, and redness), muscle pain, and joint pain. If these side effects do no resolve with time or get worse, you should let your doctor know. Your doctor may help with ways to reduce or prevent these symptoms by prescribing you alternative medicine or adjusting the dose.

You should not take this medicine if you have a knee joint infection or skin disease, or infection  around the area where the injection will be given. To make sure the medicine is safe for you, let your doctor know if you have any problems with your heart, kidneys, or liver. You should also let your doctor know all the other medicines you are taking before using this medicine. If you are pregnant or breastfeeding, consult your doctor first before taking this medicine.

Uses of Osteo One Injection

Benefits of Osteo One Injection

Treatment of Osteoarthritis
Osteoarthritis is a condition that causes pain and swelling in the joints of your hands, knees, hips and spine. Osteo One Injection is most commonly used to treat knee pain caused by osteoarthritis. Osteo One Injection helps restore the synovial fluid which helps in lubricating and cushioning the joint during movement. This way it restores the mobility and reduce the pain. Mild symptoms of osteoarthritis can sometimes be managed by doing light exercises, losing weight and suitable footwear.

Side effects of Osteo One Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Osteo One
  • Injection site reactions (pain, swelling, redness)
  • Muscle pain
  • Joint pain

How to use Osteo One Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Osteo One Injection works

Osteo One Injection is the salt form of hyaluronic acid. It helps supplement the viscous properties of the fluid in knee joint thereby reducing friction in the joints and helps them work smoothly.

Quick tips

  • Apply an ice pack gently to the injection site for 10 to 15 minutes if you notice mild swelling or discomfort.
  • Wear a knee brace or compression sleeve post-joint injection if advised, to support the joint and reduce pressure.
  • Avoid high-impact activities like jogging, squatting, or climbing stairs for 48 hours to let the joint settle.
  • Schedule follow-up injections exactly as recommended as skipping or delaying can reduce treatment effectiveness.
  • It stabilizes the natural tear film and maintains necessary lubrication so your eyes don’t get dry and irritated.

Safety advice

Alcohol

Alcohol

SAFE
Consuming alcohol with Osteo One Injection does not usually cause any harmful side effects.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Osteo One Injection during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Osteo One Injection during breastfeeding is not available. Please consult your doctor.
Driving

Driving

SAFE
Osteo One Injection does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Osteo One Injection in patients with kidney disease. Please consult your doctor.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Osteo One Injection in patients with liver disease.

Frequently asked questions

Osteo One Injection is used for relieving knee joint pain from osteoarthritis. It works by providing cushioning in arthritic joints, acts as a shock absorber, and lubricates joints to improve mobility.
Osteo One Injection contains purified sodium hyaluronate, a natural substance found in joint fluid. It helps cushion and lubricate the knee, making movement easier and reducing pain caused by cartilage breakdown in osteoarthritis.
Individuals should not use Osteo One Injection if they are allergic to sodium hyaluronate, or if they have an infection or skin disease near the injection site. Always inform your doctor of your medical history before receiving the injection.
After taking Osteo One Injection injection, you should avoid strenuous activities and prolonged standing or walking (over 1 hour) for 48 hours after each injection. This helps reduce the risk of joint irritation and swelling.
During treatment, the area will be cleaned and sterilized, a local anesthetic may be used, and the injection will be given directly into the joint. The procedure takes about 10-15 minutes. You may need multiple injections over several weeks.
The initial relief may be experienced in a few days to a week. However, the maximum benefit may take a few weeks to months. Individual results vary. Some patients may need repeated treatments.
Post-injection care includes avoiding strenuous activities for 48 hours, applying ice if needed, following activity restrictions given by your doctor, keeping the injection site clean, and always attending follow-up appointments.
The treatment schedule varies, and an individual may typically need 3-5 injections. Each injection may be given weekly or as prescribed and may need periodic maintenance. However, the treatment regimen is based on individual response and determined by your doctor.
Yes, you can get Osteo One Injection in both knees, but each knee should be treated with a separate syringe and handled with sterile technique to avoid infection or cross-contamination.

Fact Box

Chemical Class

Acylaminosugars

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Osteoarthritis- Hyaluronic acid

Related lab tests

Calcium

Rheumatoid Factor IgG Antibody

Rheumatoid Factor IgM Antibody

References

  1. Sodium hyaluronate [Patient Information Leaflet]. [Accessed 27 Nov. 2019] (online) Available from:
  2. Central Drugs Standard Control Organisation (CDSCO). Sodium hyaluronate. [Accessed 02 Apr. 2019] (online) Available from:
  3. Sodium hyaluronate [Package Insert]. Doylestown, Pennsylvania: OrthogenRx, Inc. [Accessed 06 Aug. 2023]. (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Biorange Biologicals Private Limited
Address: Shop No 344 Plot No 7 Vardhman Dee Cee Plaza, Sector 11 Dwarka Delhi South West Delhi 110075 India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Osteo One Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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