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Orzithro 250 Tablet

Written By Dr. Lipika Khurana, PGDHHM, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Orzithro 250 Tablet is an antibiotic used to treat various types of bacterial infections of the respiratory tract, ear, nose, throat, lungs, skin, and eye in adults and children. It is also effective in typhoid fever and some sexually transmitted diseases like gonorrhea.
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General Information

The content is shown in English
Orzithro 250 Tablet image
Orzithro 250 Tablet image

Your child’s medicine at a glance

Orzithro 250 Tablet can be taken with or without food. Take it regularly and at a fixed time. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the return or worsening of the infection.


Common side effects seen with Orzithro 250 Tablet include diarrhea, vomiting, nausea, and stomach pain. These are usually temporary and subside with the completion of treatment. Consult your doctor if you find these side effects worry you or persist for a longer duration.


Do not use Orzithro 250 Tablet if you have a history of cholestatic jaundice or hepatic dysfunction that can be worsened with the use of Orzithro 250 Tablet. Inform your doctor if you have any previous history of allergy or heart problems before taking this medicine. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Orzithro 250 Tablet in children

Benefits of Orzithro 250 Tablet for your child

Treatment of Bacterial infections
Orzithro 250 Tablet is an antibiotic medicine that can be used to treat many different infections caused by bacteria. These include infections of the blood, brain, lungs, bones, joints, urinary tract, stomach, and intestines. It can also be used to treat sexually transmitted diseases. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.

Side effects of Orzithro 250 Tablet in children

Orzithro 250 Tablet does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Orzithro
  • Diarrhea
  • Nausea
  • Abdominal pain

How can I give Orzithro 250 Tablet to my child?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Orzithro 250 Tablet may be taken with or without food.

How Orzithro Tablet works

Orzithro 250 Tablet is an antibiotic. It works by preventing the synthesis of essential proteins required by bacteria to carry out vital functions. Thus, it stops the bacteria from growing and prevents the infection from spreading.

Quick tips

  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and be harder to treat.
  • Do not take antacids 2 hours before or after taking Orzithro 250 Tablet.
  • Stop taking Orzithro 250 Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking it.

Safety advice

Kidney

Kidney

CAUTION
Orzithro 250 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Orzithro 250 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Orzithro with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Domperidone (Oral Route)

Do not consume Domperidone with Azithromycin.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Orzithro 250 Tablet is safe if used at prescribed doses for the prescribed duration as advised by your doctor.
You should inform your doctor if you do not notice any improvement in your symptoms after 3 days of taking Orzithro 250 Tablet. Also, if your symptoms get worse, inform your doctor immediately.
Orzithro 250 Tablet starts working within a few hours of taking it. You may notice an improvement in symptoms after a few days. Do not stop taking the medicine without completing the course mentioned by your doctor. Stopping the medicine without consulting your doctor may cause the infection to come back, which may be more difficult to treat.
Generally, it is recommended that patients taking Orzithro 250 Tablet should avoid taking any antacid with this medicine, as this can affect the overall effectiveness of Orzithro 250 Tablet. It is also recommended to avoid exposure to sunlight or tanning beds as Orzithro 250 Tablet increases the risk of sunburn.
Orzithro 250 Tablet is an antibiotic that is used for the treatment of many bacterial infections. Compared to other antibiotics, Orzithro 250 Tablet has a longer half-life, which means that it stays in the body for a long time, because of which it is given once a day and for a short period. Other antibiotics comparatively have a shorter half-life and are usually given twice, thrice, or four times a day.

Fact Box

Chemical Class

Aminoglycosides

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Macrolides

References

  1. Chambers HF, Deck DH. Tetracyclines, Macrolides, Clindamycin, Chloramphenicol, Streptogramins, & Oxazolidiones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 801.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 117-20.
  3. Azithromycin [EMC Label]. Frimley, Camberley: Sandoz Ltd.; 2018. [Accessed 31 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 31 Mar. 2019] (online) Available from:
  5. Azithromycin [Prescribing Information]. Panchmahal, Gujarat: Alembic Pharmaceuticals Limited; 2019. [Accessed 09 Jun, 2023] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Origam Pharmocrats
Address: AO.Kalpatru, AV.6, RT Street,20th Cross, BVK Iyenger Road ,Bengaluru 560053, Karnataka, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Orzithro 250 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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