Onstart Syrup is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy, or radiotherapy.

Onstart Syrup may be used alone or with other medications and can be taken with or without food. Your doctor will suggest the appropriate dose depending on what you are taking it for. The first dose is normally taken before the start of surgery, chemotherapy, or radiotherapy. After these treatments, take any further doses as prescribed by your doctor (normally only for a few days at most). Take it regularly at the same time(s) each day to get the most benefit. Be careful not to take too much.

This medicine does not relieve other side effects associated with cancer treatments. Also, it has little effect on vomiting caused by motion sickness. The most common side effects of taking this medicine include headache, diarrhea, or constipation and feeling tired. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicines you might be taking, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.

Uses of Onstart Syrup

Side effects of Onstart Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Onstart

Fatigue
Headache
Constipation
Diarrhea

How to use Onstart Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Onstart Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Onstart Syrup works

Onstart Syrup is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Onstart Syrup. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Onstart Syrup during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Onstart Syrup during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Onstart Syrup alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Onstart Syrup is safe to use in patients with kidney disease. No dose adjustment of Onstart Syrup is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Onstart Syrup in patients with liver disease. Please consult your doctor.

What if you forget to take Onstart Syrup?

If you miss a dose of Onstart Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Onstart Syrup

₹24.2/Syrup

Emless Syrup

Indian Drugs & Pharmaceuticals Ltd

₹33.04/syrup

32% costlier

Ronset Syrup

RKM Health Care

₹39.18/syrup

57% costlier

Joset Syrup

John Biotech Pvt Ltd

₹34/syrup

36% costlier

Emon Syrup

Embiotic Laboratories Pvt Ltd

₹35.55/syrup

42% costlier

Megaset Syrup

St Morrison

₹34/syrup

36% costlier

View all substitutes

Quick tips

You have been prescribed Onstart Syrup for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
It is fast-acting and starts working within 30 minutes.
If you vomit within one hour of taking a dose, take another dose.
Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Fact Box

Chemical Class

Carbazole Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

Interaction with drugs

Taking Onstart with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Amisulpride (Oral Route) Life-threatening

Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amisulpride.

Amisulpride (Injection Route) Life-threatening

Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amisulpride.

Amiodarone (Oral Route) Life-threatening

Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amiodarone.

Amiodarone (Injection Route) Life-threatening

Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Amiodarone.

Aripiprazole (Oral Route) Life-threatening

Concomitant use may affect heart rhythm and may be fatal. Do not consume Ondansetron with Aripiprazole.

View all drug interactions

Patient concerns

What is side effect of primolut n

Dr. Megha Tuli

Obstetrics and Gynaecology

Bloating, pain abdomen, nausea, vomiting etc are common side of Primolut.

Vomiting, nausea neck pain backside

Dr. Vijay Verma

ENT

Neck pain may be due to nausea NAD vomiting Visit physician for the same

Vomiting nausea problem and fever

Dr. Gopal Bansilal Samdani

Paediatrics

Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.

FAQs

How quickly does Onstart Syrup work?

Onstart Syrup starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

What are the side effects of Onstart Syrup?

The most common side effects of Onstart Syrup are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

When should you take Onstart Syrup?

Onstart Syrup should be taken with a full glass of water, with or without food. It should be used exactly as per the dose and duration advised by the doctor. Usually, the first dose of Onstart Syrup is taken before the start of your surgery, chemotherapy or radiation treatment.

Is Onstart Syrup a steroid?

No, Onstart Syrup is an antiemetic and not a steroid. Onstart Syrup is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.

Does Onstart Syrup work for seasickness?

No, Onstart Syrup does not work for seasickness. This is because Onstart Syrup has very little effect on the nausea associated with motion sickness.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
Ondansetron. Portage, IN: Monosol Rx, LLC; 1991 [revised Jul. 2010]. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Ondansetron hydrochloride [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 25 Jul. 2024] (online) Available from:

Marketer details

Name: Punjab Formulations Ltd

Address: 339, LAXMI PLAZA, LAXMI INDUSTRIAL ESTATE, NEW LINK ROAD, ANDHERI (WEST) MUMBAI MH 400053 IN , - , .

Country of origin: India

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