Ondestar 4MD Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 21 Sep 2025 | 06:09 PM (IST)

Ondestar 4MD Tablet is a medicine used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to surgery, cancer drug therapy, or radiotherapy.

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Ondestar 4MD Tablet

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Vomikind -MD 4 Tablet

strip of 10 tablet dt

Ondansetron (4mg)

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General Information

Contains

Ondansetron (4mg)

Marketer

Bioncare Pharma

Storage

Store below 30°C

The content is shown in English

Product introduction

Ondestar 4MD Tablet may be used alone or with other medications and can be taken with or without food. Your doctor will suggest the appropriate dose depending on what you are taking it for. The first dose is normally taken before the start of surgery, chemotherapy, or radiotherapy. After these treatments, take any further doses as prescribed by your doctor (normally only for a few days at most). Take it regularly at the same time(s) each day to get the most benefit. Be careful not to take too much.

Ondestar 4MD Tablet does not relieve other side effects associated with cancer treatments. Also, it has little effect on vomiting caused by motion sickness. The most common side effects of taking this medicine include headache, diarrhea or constipation, and feeling tired. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

Before taking Ondestar 4MD Tablet, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicines you might be taking, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.

Uses of Ondestar Tablet DT

Benefits of Ondestar Tablet DT

Treatment and prevention of Vomiting
Ondestar 4MD Tablet is used to prevent and treat vomiting by blocking signals in the brain that trigger the vomiting reflex. It provides quick relief and helps patients feel more comfortable, especially after surgery, chemotherapy, or certain illnesses.

Treatment and prevention of Nausea
Ondestar 4MD Tablet helps relieve nausea by blocking chemical signals in the brain that cause the feeling of sickness. It is especially useful for nausea related to chemotherapy, radiation therapy, or surgery, making patients feel more at ease.

Side effects of Ondestar Tablet DT

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ondestar

Fatigue
Headache
Constipation
Diarrhea

How to use Ondestar Tablet DT

Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Ondestar 4MD Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Ondestar Tablet DT works

Ondestar 4MD Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

All substitutes for Ondestar 4MD Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Ondestar 4MD Tablet for the prevention of nausea and vomiting caused by surgery or due to chemotherapy and radiotherapy.
It is fast-acting and starts working within 30 minutes.
If you vomit within one hour of taking a dose, take another dose.
Avoid heavy meals and try eating small, nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Safety advice

Alcohol

CAUTION

Caution is advised when consuming alcohol with Ondestar 4MD Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Ondestar 4MD Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Ondestar 4MD Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Ondestar 4MD Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Ondestar 4MD Tablet is safe to use in patients with kidney disease. No dose adjustment of Ondestar 4MD Tablet is recommended.
However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.

Liver

CAUTION

Ondestar 4MD Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Ondestar 4MD Tablet may be needed. Please consult your doctor.

Interaction with drugs

Taking Ondestar with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Disopyramide (Oral Route)

Do not consume Ondansetron with Disopyramide.

Life-threatening

Amiodarone (Oral Route)

Do not consume Ondansetron with Amiodarone.

Life-threatening

Amiodarone (Injection Route)

Do not consume Ondansetron with Amiodarone.

Life-threatening

Amisulpride (Oral Route)

Do not consume Ondansetron with Amisulpride.

Life-threatening

Amisulpride (Injection Route)

Do not consume Ondansetron with Amisulpride.

Frequently asked questions

How quickly does Ondestar 4MD Tablet work?

Ondestar 4MD Tablet starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.

What are the side effects of Ondestar 4MD Tablet?

The most common side effects of Ondestar 4MD Tablet are constipation, diarrhea, fatigue, and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.

When should you take Ondestar 4MD Tablet?

Ondestar 4MD Tablet should be taken with a full glass of water, with or without food. It should be used exactly as per the dose and duration advised by the doctor. Usually, the first dose of Ondestar 4MD Tablet is taken before the start of your surgery, chemotherapy, or radiation treatment.

Is Ondestar 4MD Tablet a steroid?

No, Ondestar 4MD Tablet is an antiemetic and not a steroid. Ondestar 4MD Tablet is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting, which is commonly observed after surgery or due to cancer chemotherapy.

Does Ondestar 4MD Tablet work for seasickness?

No, Ondestar 4MD Tablet does not work for seasickness. This is because Ondestar 4MD Tablet has very little effect on the nausea associated with motion sickness.

Fact Box

Chemical Class

Carbazole Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin 5-HT3 Receptor Antagonists

References

Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
Ondansetron. Portage, IN: Monosol Rx, LLC; 1991 [revised Jul. 2010]. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Ondansetron hydrochloride [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 25 Jul. 2024] (online) Available from:
Ondansetron [Prescribing Information]. Mahwah, NJ: Glenmark Pharmaceuticals Inc.; 2021. [Accessed 19 Mar. 2025] (online) Available from:
Ondansetron [Prescribing Information]. 2022. [Accessed 19 Mar. 2025] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bioncare Pharma
Address: Tapadia Mall, Sector C-2, Town Center, Cidco, Aurangabad, Maharashtra 431003

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Ondestar 4MD Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Ondestar Tablet DT

Benefits of Ondestar Tablet DT

Side effects of Ondestar Tablet DT

How to use Ondestar Tablet DT

How Ondestar Tablet DT works

All substitutes for Ondestar 4MD Tablet

Vomikind -MD 4 Tablet

Zofer MD 4 Tablet

Emigo-MD Tablet

Vomiliv 4mg Tablet DT

Ondiwel 4mg Tablet DT

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Disopyramide (Oral Route)

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Amisulpride (Oral Route)

Amisulpride (Injection Route)

Frequently asked questions

How quickly does Ondestar 4MD Tablet work?

What are the side effects of Ondestar 4MD Tablet?

When should you take Ondestar 4MD Tablet?

Is Ondestar 4MD Tablet a steroid?

Does Ondestar 4MD Tablet work for seasickness?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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