ON-Sure Tablet is an antiemetic medicine commonly used to control nausea and vomiting due to certain medical conditions like stomach upset. It is also used to prevent nausea and vomiting caused due to any surgery, cancer drug therapy, or radiotherapy.
ON-Sure Tablet may be used alone or with other medications and can be taken with or without food. Your doctor will suggest the appropriate dose depending on what you are taking it for. The first dose is normally taken before the start of surgery, chemotherapy, or radiotherapy. After these treatments, take any further doses as prescribed by your doctor (normally only for a few days at most). Take it regularly at the same time(s) each day to get the most benefit. Be careful not to take too much.
This medicine does not relieve other side effects associated with cancer treatments. Also, it has little effect on vomiting caused by motion sickness. The most common side effects of taking this medicine include headache, diarrhea, or constipation and feeling tired. These symptoms should disappear when you stop taking the medicine. However, if these side effects bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.
Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also, tell your doctor about any other medicines you might be taking, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of ON-Sure
Fatigue
Headache
Constipation
Diarrhea
How to use ON-Sure Tablet MD
Take this medicine in the dose and duration as advised by your doctor. Do not handle the tablets with wet hands. Put it in your mouth but do not swallow it. ON-Sure Tablet may be taken with or without food, but it is better to take it at a fixed time.
How ON-Sure Tablet MD works
ON-Sure Tablet is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.
Safety advice
Alcohol
CAUTION
Caution is advised when consuming alcohol with ON-Sure Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Information regarding the use of ON-Sure Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of ON-Sure Tablet during breastfeeding is not available. Please consult your doctor.
Driving
CONSULT YOUR DOCTOR
It is not known whether ON-Sure Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
ON-Sure Tablet is safe to use in patients with kidney disease. No dose adjustment of ON-Sure Tablet is recommended. However, inform your doctor if you have an underlying kidney disease. Limited information is available in patients taking this medicine for more than one day.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of ON-Sure Tablet in patients with liver disease. Please consult your doctor.
What if you forget to take ON-Sure Tablet MD?
If you miss a dose of ON-Sure Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
HELLO SIR Mr. PATIENT is my Father. He is having Diabetes from a long 30 years. Presently from past few months he is facing problems with leg pain and constipation. Also more of the time he murmur some of the old memories and present situation many times. He is consuming a tablet called Gravitor 60mg as suggested by doctor three times a day. Please suggest if any tests or any medicine can be prescribed to him to recover soon.
Sir I want to know about the graviola fruit I have heard that it is an anticancer fruit,it helps fighting cancer cells unlike chemo medicine without harming good cells like n prevents hairloss n other harms done with chemotherapy. Please tell thr truth
Dr. Deepak Kumar Soni
Ayurveda
Not sure Kindly check the research of fruit on internet & Research paper
hello dr!! me n my husband had sex last tym aftr it n my pragnancy test is negative but nw i am hving lots of problem lyk short periods n feeling like vomiting n abdomen pain i want to knw dat am i pragnant or not?? or there is another problem wid me am very confused
Dr. Suman Rao
Obstetrics and Gynaecology
Get a serum beta hCG done to be sure about pregnancy.
I have a swelling which is palpable and pain is felt,fever 2days,also vomiting only 1 time in night,not feeling well, swelling earliar i felt was like lymph node but it is smaller and it has reduced a slight after heating it with cloth my physician recommended me cefakind I want if any ayur.medicie available
Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.
ON-Sure Tablet starts working within half an hour to 2 hours. It dissolves rapidly into the bloodstream and starts showing its effect.
What are the side effects of ON-Sure Tablet?
The most common side effects of ON-Sure Tablet are constipation, diarrhea, fatigue and headache. However, these are usually not bothersome and resolve on their own after some time. Consult your doctor if these persist or worry you.
When should you take ON-Sure Tablet?
ON-Sure Tablet should be taken with a full glass of water, with or without food. It should be used exactly as per the dose and duration advised by the doctor. Usually, the first dose of ON-Sure Tablet is taken before the start of your surgery, chemotherapy or radiation treatment.
Is ON-Sure Tablet a steroid?
No, ON-Sure Tablet is an antiemetic and not a steroid. ON-Sure Tablet is a selective 5-HT3 receptor antagonist. It is prescribed for the prevention and treatment of nausea and vomiting which is commonly observed after surgery or due to cancer chemotherapy.
Does ON-Sure Tablet work for seasickness?
No, ON-Sure Tablet does not work for seasickness. This is because ON-Sure Tablet has very little effect on the nausea associated with motion sickness.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1341-42.
Katzung BG. Histamine, Serotonin, & the Ergot Alkaloids. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 285
Ondansetron. Portage, IN: Monosol Rx, LLC; 1991 [revised Jul. 2010]. [Accessed 28 Mar. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Ondansetron. [Updated 2019 Feb 7]. [Accessed 20 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
Ondansetron hydrochloride [Prescribing Information]. Research Triangle Park, NC: GlaxoSmithKline; 2016. [Accessed 25 Jul. 2024] (online) Available from:
Country of origin: India Expires on or after: March, 2025
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