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Omefol Capsule

Omeprazole (NA)
Genuine
Authenticity Assured
Prescription
required
Omefol Capsule is a medicine that helps reduce the amount of acid made by the stomach. It is used for the treatment of peptic ulcer, gastric ulcer, gastroesophageal reflux disease (GERD), and for the management of Zollinger-Ellison syndrome, a rare condition in which the stomach produces too much acid.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 27 Nov 2025 | 02:48 PM (IST)
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General Information

The content is shown in English
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Product introduction

Take Omefol Capsule exactly as directed by your doctor, usually once daily before a meal. Swallow it whole; do not chew or crush it. To get the most benefit, take it regularly at the same time each day. Continue the full course even if you feel better, as stopping too soon may cause symptoms to return. Along with treatment, avoid irritants such as alcohol, tobacco, and spicy or acidic foods. Eat smaller, more frequent meals and do not lie down immediately after eating.


The most common side effects include headache, stomach pain, nausea, diarrhea, vomiting, and gas. These are generally mild and often go away as your body adjusts to the medicine. If diarrhea is severe, persistent, or watery, inform your doctor. Staying hydrated and maintaining a balanced diet can help reduce discomfort.


Before taking this medicine, tell your doctor if you have liver disease or any kidney problems. Long-term or high-dose use may increase the risk of bone fractures, low vitamin B12 or magnesium levels, or fundic gland polyps in the stomach. Therefore, the medicine should be used at the lowest effective dose for the shortest possible time. Seek immediate help if you notice signs of severe allergic reaction, such as swelling, breathing difficulty, or rash with blisters. Do not take Omefol Capsule if you are allergic to omeprazole or any ingredients in the medicine. Inform your doctor about all other medicines you take, as Omefol Capsule can affect how other medicines work.

Uses of Omefol Capsule

Benefits of Omefol Capsule

Treatment of Stomach ulcers
In gastric ulcers, Omefol Capsule lowers acid levels in the stomach, protecting the stomach wall from further damage and giving it time to recover. Regular use as prescribed can help relieve symptoms such as burning pain and discomfort, and promote complete ulcer healing.
Treatment of Gastroesophageal reflux disease (Acid reflux)
Omefol Capsule provides relief from the burning sensation of acid reflux and heartburn caused by gastroesophageal reflux disease (GERD). It reduces acid production, preventing stomach acid from flowing back into the food pipe, and helps heal irritation or inflammation of the esophagus, improving comfort and digestion.
Treatment of Peptic ulcer disease
Omefol Capsule helps relieve pain and promotes healing in peptic ulcers (duodenal ulcers) by reducing excess stomach acid that irritates the ulcer lining. It blocks acid production and allows the damaged tissue in the stomach and upper intestine to heal properly. It also helps prevent the ulcer from coming back.
Management of Zollinger-Ellison syndrome
For people with Zollinger-Ellison syndrome, where the stomach produces too much acid, Omefol Capsule helps control acid secretion and prevents complications such as ulcers. It provides long-term management of acid levels, improving quality of life and preventing damage to the stomach and intestines.

Side effects of Omefol Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Omefol
  • Abdominal pain
  • Flatulence
  • Headache
  • Nausea
  • Diarrhea
  • Vomiting

How to use Omefol Capsule

Take this medicine in the dose and duration as advised by your doctor. Omefol Capsule is to be taken on an empty stomach.

How Omefol Capsule works

Omefol Capsule works by specifically blocking an enzyme system known as the “acid pump” in the stomach lining. This enzyme is responsible for the final step in the production of gastric acid. Inhibiting this pump reduces both the volume and acidity of stomach secretions, providing lasting acid suppression and promoting healing of acid-related conditions such as ulcers and reflux disease.

All substitutes for Omefol Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Take it before a meal, preferably in the morning, 30–60 minutes before breakfast, to get the best effect.
  • Take it at the same time every day to help maintain consistent acid control.
  • Avoid trigger foods, such as spicy, fatty, or acidic foods, and limit caffeine and alcohol intake.
  • Avoid laying down right after eating. Wait at least 2–3 hours after meals before lying down to prevent acid reflux.
  • Combine the treamtent with with lifestyle changes, such as healthy weight and quitting smoking.
  • If you still experience heartburn or indigestion after 2 weeks, consult with your doctor.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Omefol Capsule. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Omefol Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Omefol Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Omefol Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Omefol Capsule in patients with kidney disease. Please consult your doctor.
Liver

Liver

CAUTION
Omefol Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Omefol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Voriconazole (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Omeprazole may raise blood levels of Voriconazole.
Severe

Erlotinib (Oral Route)

Do not consume Erlotinib with Omeprazole. Omeprazole may reduce blood levels of Erlotinib.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Atazanavir (Oral Route)

Do not consume Atazanavir with Omeprazole. If concurrent use is essential, please consult your doctor. Omeprazole may reduce blood levels of Atazanavir.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Omefol Capsule is used to treat several acid-related stomach and intestinal conditions such as peptic ulcer, gastric ulcer, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. It helps relieve heartburn, heals ulcers, and prevents damage caused by excess acid in the stomach and food pipe.
Some people begin to feel better within a few days, but it may take up to 4 weeks for full relief. Most ulcers and reflux symptoms heal within 4 to 8 weeks of treatment, depending on your condition.
Yes, Omefol Capsule can be taken daily as prescribed. However, prolonged or unnecessary use should be avoided. Long-term use may increase the risk of bone fractures, vitamin B12 deficiency, magnesium imbalance, or fundic gland polyps. Use the lowest effective dose for the shortest duration necessary.
Some medicines can interact with Omefol Capsule. Do not take it with rilpivirine-containing medicines. Avoid combining it with St. John’s Wort or rifampin, as these can reduce its effectiveness. This medicine may also affect the way clopidogrel, warfarin, methotrexate, and digoxin work. Always inform your doctor about all other medicines or supplements you use.
Studies have not shown an increased risk of birth defects with Omefol Capsule use during pregnancy. It may be used if clearly needed under medical advice. Small amounts may pass into breast milk, but no harmful effects have been reported in infants. Always consult your doctor before use if you are pregnant or breastfeeding.
Do not stop taking it suddenly without consulting your doctor. Stopping early may cause your symptoms to return or worsen. Complete the full treatment course as directed.
Avoid drinking alcohol, smoking, or eating spicy and fatty foods, as these can worsen acid-related symptoms. Do not take it with rilpivirine or herbal products such as St. John’s Wort, as they may interfere with treatment.

Fact Box

Chemical Class

Sulfinylbenzimidazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Proton-Pump Inhibitors
100% genuine products
100% genuine products
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No contact delivery
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Fully sanitized facilities
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User feedback

Heartburn
36%
Acidity
27%
Stomach ulcers
18%
Others
18%
Poor
72%
Average
17%
Excellent
11%
Headache
33%
Abdominal pain
33%
No Side Effect
33%
Empty stomach
100%
Average
67%
Not Expensive
33%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Leeford Healthcare Ltd
Address: 203, Mangalam, Keshav Road, Sion, Mumbai-400 022, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Omefol Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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