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Olfamist Nasal Solution

Oxymetazoline (0.05% w/v)
Genuine
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Olfamist Nasal Solution is a medicine used to treat nasal congestion (blocked nose) caused by the common cold or flu, hay fever, and other allergies. It narrows the blood vessels in your nose to relieve nasal congestion and blockage.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 20 Jan 2026 | 11:00 AM (IST)
MRP ₹60
 
 
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Olfamist Nasal Solution
Olfamist Nasal Solution
bottle of 10 ml Nasal Solution
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General Information

The content is shown in English
Olfamist Nasal Solution image
Olfamist Nasal Solution image

Product introduction

Olfamist Nasal Solution should be used as you have been advised by your doctor. Normally, you should blow your nose gently before using it, keep one nostril closed while applying the medicine into the other, and then sniff hard to make sure it reaches deep into the nose. Then repeat the same for the other nostril. It provides relief very quickly and can last for several hours. It provides only temporary relief, but do not use it more often or for longer than recommended. If you use this medicine too often or for too long, it may worsen your symptoms rather than improve them.


The most common side effects are nose irritation and dryness of the mouth or throat. These are usually mild, but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.


It is generally a safe medicine. Before taking it, talk to your doctor about any health problems you have, such as heart problems, high blood pressure (hypertension), an overactive thyroid gland, or glaucoma (increased pressure in the eye), or prostate enlargement. Let your doctor know about any other medicines you are taking to make sure you are safe. Ask your doctor for advice before using this medicine if you are pregnant or breastfeeding.

Uses of Olfamist Nasal Solution

  • Treatment of Nasal congestion (blocked nose)

Benefits of Olfamist Nasal Solution

Treatment of Nasal congestion (blocked nose)
Nasal congestion occurs when the blood vessels in the nasal passages become swollen due to colds, allergies, or sinus infections, leading to a stuffy or blocked nose. This can make breathing difficult, disrupt sleep, and cause discomfort. Olfamist Nasal Solution is used to provide quick relief from nasal congestion. It works by shrinking the swollen blood vessels inside the nose, allowing for easier airflow. This helps restore normal breathing and provides relief from pressure and discomfort associated with blocked nasal passages.

Side effects of Olfamist Nasal Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Olfamist
  • Dryness
  • Dry throat
  • Irritation
  • Sneezing

How to use Olfamist Nasal Solution

Use it as advised by your doctor or check the label for directions before use.

How Olfamist Nasal Solution works

Olfamist Nasal Solution is a nasal decongestant. It works by narrowing the small blood vessels in the inner surface of the nose. This provides temporary relief from congestion or stuffiness in the nose.

Quick tips

  • Olfamist Nasal Solution works right away, and each dose provides relief for up to 12 hours. 
  • Shake the bottle before using the medicine, and clean your nose thoroughly before using the medicine.
  • Avoid deep breathing as it will cause medication to go back to the throat and make it less effective.
  • Do not share the bottle with anyone else so that you do not spread germs.
  • Olfamist Nasal Solution can make nasal congestion worse if used for more than 3 or 4 days in a row (called rebound congestion).

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Olfamist Nasal Solution is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Olfamist Nasal Solution during breastfeeding is not available. Please consult your doctor.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Olfamist with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Furazolidone (Oral Route)

Do not consume Furazolidone with Oxymetazoline. If essential, consult your doctor.
Life-threatening

Sevoflurane (Oral Route)

Do not consume Sevoflurane with Oxymetazoline.
Life-threatening

Sevoflurane (Inhalation Route)

Do not consume Sevoflurane with Oxymetazoline.
Life-threatening

Tranylcypromine (Oral Route)

Do not consume Tranylcypromine with Oxymetazoline. If Tranylcypromine is essential, ensure a gap of at least 2 weeks after discontinuing Oxymetazoline. Please consult your doctor.
Moderate

Selegiline (Oral Route)

Do not consume Selegiline with Oxymetazoline. If concurrent use is essential, your doctor may monitor your blood pressure frequently.

Frequently asked questions

Treatment with Olfamist Nasal Solution does not cause mental addiction. However, patients may get physically addicted such that they may feel an urge to use Olfamist Nasal Solution. Hence, it should only be used at prescribed doses for the prescribed duration as advised by your doctor.
No, Olfamist Nasal Solution is not a steroid or an antihistamine. It belongs to a class of medications called adrenergic medicines that are used as nasal decongestants (to relieve congestion of the nose).
Olfamist Nasal Solution is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
There are no such reports that suggest the occurrence of side effects such as cataract, insomnia (inability to sleep), or drowsiness during treatment with Olfamist Nasal Solution. However, Olfamist Nasal Solution can raise blood pressure when taken with medicines that are used to treat depression, like selegiline and moclobemide. It can also decrease the effect of medicines used to treat blood pressure. Hence, patients should consult doctors regarding the possible side effects and drug interactions.
Olfamist Nasal Solution should not be taken simultaneously with diphenhydramine/phenylephrine/pseudoephedrine. Consult your doctor before using any other medicine with Olfamist Nasal Solution.

Fact Box

Chemical Class

Xylenols

Habit Forming

No

Therapeutic Class

RESPIRATORY

Action Class

Sympathomimetics- Alpha-1 (Nasal)

References

  1. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 140.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1041-42.
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:
  4. Oxymetazoline Hydrochloride [Summary of Product Characteristics]. Ahmedabad, Gujarat: Zydus Lifesciences Limited; 2023.
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Strides shasun Ltd
Address: Strides Shasun Limited, (Formerly Strides Arcolab Limited), Strides House, Bilekahalli, Bannerghatta Road, Bangalore – 560076, India

Vendor Details

Country of origin: India
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