Sign in to your account
or
By signing in you agree to our
Terms & conditions
 and 
Privacy policy
sold out tag

Obiholic 10mg Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 19 Nov 2025 | 11:26 PM (IST)
Obiholic 10mg Tablet is used in alone or in combination therapy to treat primary biliary cirrhosis. It helps improve the liver function by inhibiting the production of bile acid and increasing the removal of bile acid from the liver. This reduces the bile acid in the liver and hence prevents its toxic effects.
Genuine
Authenticity Assured
Prescription
required
₹271 MRP ₹30010% off 
 
 
0
footer-icon
sku_image
Obiholic 10mg Tablet is currently sold out
Same composition alternative:
Obetohep 10mg Tablet
₹405₹448.1
Available alternative from Alkem Laboratories
Sold out
Obiholic 10mg Tablet
Obiholic 10mg Tablet
strip of 10 tablets
₹271
₹300
tag icon
Same composition
Obetohep 10mg Tablet
Obetohep 10mg Tablet
strip of 10 tablets
by Alkem Laboratories Ltd
Get by 2pm
₹405
₹34.4 per tablet

₹344

order for
₹1200

Save more with additional offers

offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon

Save more with additional offers

offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.
chevron icon
offer icon
Get cashback up to ₹500
Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.
chevron icon
offer icon
Get upto Rs.150 Cashback
Get upto Rs.150 Cashback
chevron icon

General Information

The content is shown in English
Obiholic 10mg Tablet image
Obiholic 10mg Tablet image

Product introduction

Obiholic 10mg Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete the full course of the medicine as prescribed by your doctor. Do not stop taking it until you have finished.

The most common side effects of this medicine include itching, fatigue, rash, throat pain, dizziness, constipation, joint pain, eczema, and thyroid disorders. If you experience any of these side effects that does not resolve on its own or get worse, you should let your doctor.

Before taking the medicine, tell your doctor if you have any other medical conditions. You should also let your doctor know about all the other medicines you are taking (if any), as they may affect or be affected by this medicine. Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Uses of Obiholic Tablet

Benefits of Obiholic Tablet

Treatment of Primary biliary cirrhosis
Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Obiholic 10mg Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, it is likely that you will be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

Side effects of Obiholic Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Obiholic
  • Throat pain
  • Itching
  • Fatigue
  • Abdominal discomfort
  • Rash
  • Joint pain
  • Oropharyngeal pain
  • Dizziness
  • Constipation
  • Peripheral edema
  • Palpitations
  • Fever
  • Thyroid disorders
  • Eczema

How to use Obiholic Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Obiholic 10mg Tablet may be taken with or without food.

How Obiholic Tablet works

Obiholic 10mg Tablet stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obiholic 10mg Tablet inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.

Quick tips

  • Obiholic 10mg Tablet is used for the treatment of primary biliary cirrhosis.
  • Your liver function will be monitored closely while on treatment with Obiholic 10mg Tablet.
  • Eat a well-balanced diet and indulge in some sort of physical activity daily in order to reduce fatigue and improve well-being.
  • Itching is one of the common side effects of Obiholic 10mg Tablet. Follow these tips to manage itching:
    a) Keeping cool will also tend to reduce itch, compared to being warm. Cool showers or cold flannels may be helpful.
    b)Dry skin can make the itch worse, so using liberal amounts of moisturizer is useful if you have dry skin.
    c) Do not scratch as scratching will generally make it worse. If scratching is irresistible it may help to rub the itchy area with an ice cube.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Obiholic 10mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Information regarding the use of Obiholic 10mg Tablet during pregnancy is not available. Please consult your doctor.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Obiholic 10mg Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Obiholic 10mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Obiholic 10mg Tablet is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver

Liver

CAUTION
Obiholic 10mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Obiholic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Theophylline (Oral Route)

Watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may adjust the dose of Obeticholic acid accordingly. Obeticholic acid may raise blood levels of Theophylline.
Moderate

Tizanidine (Oral Route)

Watch out for symptoms of Tizanidine side effects such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. They may adjust the dose of Tizanidine as per the observations. Obeticholic acid may raise blood levels of Tizanidine.
Moderate

Warfarin (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly. Obeticholic acid may raise blood levels of Warfarin.
Moderate

Cholestyramine (Oral Route)

To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Cholestyramine. Cholestyramine may reduce the efficacy of Obeticholic acid.
Moderate

Colesevelam (Oral Route)

To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Colesevelam. Colesevelam may reduce the efficacy of Obeticholic acid.

Frequently asked questions

Obiholic 10mg Tablet is used to treat primary biliary cholangitis (PBC), a liver condition where bile builds up and damages the liver, especially in patients who do not fully respond to first-line therapy.
Individuals should not take Obiholic 10mg Tablet if they are allergic to obeticholic acid or any ingredients in the medicine, or if they have a complete blockage of the bile ducts (obstructive cholestasis).
Yes, in some cases, Obiholic 10mg Tablet can cause worsening liver function or severe itching. Your liver function will be closely monitored by your doctor during treatment.
During Obiholic 10mg Tablet treatment, if you experience severe itching, yellowing of the skin or eyes, dark urine, severe stomach pain, or swelling, you should seek medical advice right away.
Special caution is needed for people with liver cirrhosis while taking Obiholic 10mg Tablet. Dosage adjustment and close monitoring by your doctor are important to avoid liver complications.
You should tell your doctor if you have gallstones or any history of gallbladder problems before taking Obiholic 10mg Tablet, as this might affect your treatment plan.
While you are on Obiholic 10mg Tablet treatment, maintain regular liver checkups, avoid alcohol and liver toxins, report new or worsening symptoms early, and follow your doctor’s guidance on diet and exercise.

Fact Box

Chemical Class

Dihydroxy bile acid derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotective Agents
Related products
Products related to Obiholic 10mg Tablet
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Excellent
100%
No Side Effect
100%
With food
100%
<h3 class=titleMediumExtraBold>Want to know more</h3>

Want to know more

We provide you with authentic, trustworthy and relevant information
<h3 class=titleMediumExtraBold>Have issue with the content</h3>

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mankind Pharma Ltd
Address: 208, Okhla Industrial Estate, Phase III, New Delhi - 110020

Vendor Details

Country of origin: India
Why we need a prescription?
Image of Step
Provide right medicines
Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose
Image of Step
In accordance with the law
Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
close sheet