Obeticholic acid

Last updated 10 Apr 2025 | 04:43 AM (UTC)

Obeticholic acid Uses

Obeticholic acid is used in the treatment of cholestatic liver diseases, primary biliary cirrhosis, alcoholic fatty liver disease and Non-alcoholic fatty liver disease.

How Obeticholic acid works

Obeticholic acid stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obeticholic acid inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.

Common side effects of Obeticholic acid

Itching, Fatigue, Abdominal pain, Abdominal discomfort, Rash, Joint pain, Oropharyngeal pain, Dizziness, Constipation, Peripheral edema, Palpitations, Fever, Thyroid disorders, Eczema

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Medicine brands for Obeticholic acid

Obilnex

Qonexa Life Care Private Limited

Nexwin Pharma Pvt. Ltd.

₹390 to ₹390

1 variant(s)

Obedec

Mits Healthcare Pvt Ltd

Astonea Labs Private Limited

₹206 to ₹378

2 variant(s)

Expert advice for Obeticholic acid

It protects the liver cells from toxins and helps the liver to perform its normal functions.
It should preferably be taken after meals. One of the doses should always be taken after your evening meal.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if diarrhea persists or if you find blood in your stools.
Do not take antacids that contain aluminum while you are taking Obeticholic acid as this decreases the amount of Obeticholic acid absorbed by your body.
Consult with your doctor if you are pregnant, planning pregnancy or breastfeeding.