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Obetee 5mg Tablet

Obeticholic acid (5mg)

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Obetee 5mg Tablet is used in alone or in combination therapy to treat primary biliary cirrhosis. It helps improve the liver function by inhibiting the production of bile acid and increasing the removal of bile acid from the liver. This reduces the bile acid in the liver and hence prevents its toxic effects.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 30 Mar 2026 | 04:26 PM (IST)

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10 tablets

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General Information

Contains

Obeticholic acid (5mg)

Marketer

Synokem Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Obetee 5mg Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete the full course of the medicine as prescribed by your doctor. Do not stop taking it until you have finished.

The most common side effects of this medicine include itching, fatigue, rash, throat pain, dizziness, constipation, joint pain, eczema, and thyroid disorders. If you experience any of these side effects that does not resolve on its own or get worse, you should let your doctor.

Before taking the medicine, tell your doctor if you have any other medical conditions. You should also let your doctor know about all the other medicines you are taking (if any), as they may affect or be affected by this medicine. Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Uses of Obetee Tablet

Cholestatic liver diseases
Alcoholic fatty liver disease
Non-alcoholic fatty liver disease
Treatment of Primary biliary cirrhosis

Benefits of Obetee Tablet

Treatment of Primary biliary cirrhosis
Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Obetee 5mg Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, it is likely that you will be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

Side effects of Obetee Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Obetee

Throat pain
Itching
Fatigue
Abdominal discomfort
Rash
Joint pain
Oropharyngeal pain
Dizziness
Constipation
Peripheral edema
Palpitations
Fever
Thyroid disorders
Eczema

How to use Obetee Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Obetee 5mg Tablet may be taken with or without food.

How Obetee Tablet works

Obetee 5mg Tablet stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obetee 5mg Tablet inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.

All substitutes for Obetee 5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Obetee 5mg Tablet is used for the treatment of primary biliary cirrhosis.
Your liver function will be monitored closely while on treatment with Obetee 5mg Tablet.
Eat a well-balanced diet and indulge in some sort of physical activity daily in order to reduce fatigue and improve well-being.
Itching is one of the common side effects of Obetee 5mg Tablet. Follow these tips to manage itching:
a) Keeping cool will also tend to reduce itch, compared to being warm. Cool showers or cold flannels may be helpful.
b)Dry skin can make the itch worse, so using liberal amounts of moisturizer is useful if you have dry skin.
c) Do not scratch as scratching will generally make it worse. If scratching is irresistible it may help to rub the itchy area with an ice cube.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Obetee 5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Obetee 5mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Obetee 5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Obetee 5mg Tablet does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Obetee 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Obetee 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Obetee with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Theophylline (Oral Route)

Watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may adjust the dose of Obeticholic acid accordingly. Obeticholic acid may raise blood levels of Theophylline.

Moderate

Tizanidine (Oral Route)

Watch out for symptoms of Tizanidine side effects such as breathlessness, fatigue, drowsiness, sedation or faintness or vomiting and consult your doctor if you experience them. They may adjust the dose of Tizanidine as per the observations. Obeticholic acid may raise blood levels of Tizanidine.

Moderate

Warfarin (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly. Obeticholic acid may raise blood levels of Warfarin.

Moderate

Cholestyramine (Oral Route)

To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Cholestyramine. Cholestyramine may reduce the efficacy of Obeticholic acid.

Moderate

Colesevelam (Oral Route)

To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Colesevelam. Colesevelam may reduce the efficacy of Obeticholic acid.

Frequently asked questions

What is Obetee 5mg Tablet used for?

Obetee 5mg Tablet is used to treat primary biliary cholangitis (PBC), a liver condition where bile builds up and damages the liver, especially in patients who do not fully respond to first-line therapy.

Who should not take Obetee 5mg Tablet?

Individuals should not take Obetee 5mg Tablet if they are allergic to obeticholic acid or any ingredients in the medicine, or if they have a complete blockage of the bile ducts (obstructive cholestasis).

Can Obetee 5mg Tablet cause serious liver problems?

Yes, in some cases, Obetee 5mg Tablet can cause worsening liver function or severe itching. Your liver function will be closely monitored by your doctor during treatment.

During Obetee 5mg Tablet treatment, what symptoms should lead me to call my doctor immediately?

During Obetee 5mg Tablet treatment, if you experience severe itching, yellowing of the skin or eyes, dark urine, severe stomach pain, or swelling, you should seek medical advice right away.

Is Obetee 5mg Tablet safe for people with liver cirrhosis?

Special caution is needed for people with liver cirrhosis while taking Obetee 5mg Tablet. Dosage adjustment and close monitoring by your doctor are important to avoid liver complications.

Can I take Obetee 5mg Tablet if I have gallstones?

You should tell your doctor if you have gallstones or any history of gallbladder problems before taking Obetee 5mg Tablet, as this might affect your treatment plan.

What lifestyle advice should I follow while on Obetee 5mg Tablet?

While you are on Obetee 5mg Tablet treatment, maintain regular liver checkups, avoid alcohol and liver toxins, report new or worsening symptoms early, and follow your doctor’s guidance on diet and exercise.

Fact Box

Chemical Class

Dihydroxy bile acid derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotective Agents

Related lab tests

Alkaline Phosphatase, Serum

Bilirubin Direct

Bilirubin Total

Glycosylated Hemoglobin

Liver Function Test

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Synokem Pharmaceuticals Ltd
Address: 14/486, Sunder Vihar, Outer Ring , Road, Paschim Vihar, New, Delhi-110 087, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Obetee 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Obetee 5mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Obetee Tablet

Benefits of Obetee Tablet

Side effects of Obetee Tablet

How to use Obetee Tablet

How Obetee Tablet works

All substitutes for Obetee 5mg Tablet

Obetohep 5mg Tablet

Ocabile 5 Tablet

Ocahep 5mg Tablet

Obenow 5mg Tablet

Obil 5mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Theophylline (Oral Route)

Tizanidine (Oral Route)

Warfarin (Oral Route)

Cholestyramine (Oral Route)

Colesevelam (Oral Route)

Frequently asked questions

What is Obetee 5mg Tablet used for?

Who should not take Obetee 5mg Tablet?

Can Obetee 5mg Tablet cause serious liver problems?

During Obetee 5mg Tablet treatment, what symptoms should lead me to call my doctor immediately?

Is Obetee 5mg Tablet safe for people with liver cirrhosis?

Can I take Obetee 5mg Tablet if I have gallstones?

What lifestyle advice should I follow while on Obetee 5mg Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Alkaline Phosphatase, Serum

Bilirubin Direct

Bilirubin Total

Glycosylated Hemoglobin

Liver Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests