Obenow 5mg Tablet is used in alone or in combination therapy to treat primary biliary cirrhosis. It helps improve the liver function by inhibiting the production of bile acid and increasing the removal of bile acid from the liver. This reduces the bile acid in the liver and hence prevents its toxic effects.

Obenow 5mg Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. You should always complete the full course of the medicine as prescribed by your doctor. Do not stop taking it until you have finished.

The most common side effects of this medicine include itching, fatigue, rash, throat pain, dizziness, constipation, joint pain, eczema, and thyroid disorders. If you experience any of these side effects that does not resolve on its own or get worse, you should let your doctor.

Before taking the medicine, tell your doctor if you have any other medical conditions. You should also let your doctor know about all the other medicines you are taking (if any), as they may affect or be affected by this medicine. Consult your doctor before using this medicine if you are pregnant or breastfeeding.

Uses of Obenow Tablet

Treatment of Primary biliary cirrhosis

Benefits of Obenow Tablet

In Treatment of Primary biliary cirrhosis

Primary biliary cholangitis is a type of liver disease that gradually gets worse over time. It does not always have symptoms but, over time, it can lead to liver failure. Obenow 5mg Tablet is used to treat this condition and may be used by itself or with other medicines. It can help prevent or delay liver damage in most people, especially if you start taking it in the early stages. Once you start this treatment, it is likely that you will be taking it for the rest of your life. To make the medicine more effective and for general health benefits, you can help yourself by stopping smoking, keeping a healthy weight, and not drinking too much alcohol.

Side effects of Obenow Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Obenow

Throat pain
Itching
Fatigue
Abdominal discomfort
Rash
Joint pain
Oropharyngeal pain
Dizziness
Constipation
Peripheral edema
Palpitations
Fever
Thyroid disorders
Eczema

How to use Obenow Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Obenow 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Obenow Tablet works

Obenow 5mg Tablet stimulates Farnesoid X receptor (FXR), a chemical that regulates synthesis and transport of bile acid, lipid metabolism and regulation of glucose levels. Obenow 5mg Tablet inhibits bile acid synthesis and increases bile acid secretions. This reduces the bile acid pool in the liver and hence prevents its toxic effects. Therefore, it helps to improve liver function.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Obenow 5mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Obenow 5mg Tablet during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Obenow 5mg Tablet during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Obenow 5mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

SAFE IF PRESCRIBED

Obenow 5mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Obenow 5mg Tablet may not be needed in these patients. Please consult your doctor.

Liver

CAUTION

Obenow 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Obenow 5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Obenow Tablet?

If you miss a dose of Obenow 5mg Tablet, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Obenow 5mg Tablet

₹31.89/Tablet

Ocanash 5mg Tablet

Macleods Pharmaceuticals Pvt Ltd

₹21.5/tablet

33% cheaper

Obil 5mg Tablet

Astonea Labs Private Limited

₹21.3/tablet

33% cheaper

Ocanat 5mg Tablet

Natco Pharma Ltd

₹24.2/tablet

24% cheaper

Ocabile 5 Tablet

Torrent Pharmaceuticals Ltd

₹23.4/tablet

27% cheaper

Obitocip 5 Tablet

Cipla Ltd

₹19.4/tablet

39% cheaper

View all substitutes

Quick tips

Obenow 5mg Tablet is used for the treatment of primary biliary cirrhosis.
Your liver function will be monitored closely while on treatment with Obenow 5mg Tablet.
Eat a well-balanced diet and indulge in some sort of physical activity daily in order to reduce fatigue and improve well-being.
Itching is one of the common side effects of Obenow 5mg Tablet. Follow these tips to manage itching:
a) Keeping cool will also tend to reduce itch, compared to being warm. Cool showers or cold flannels may be helpful.
b)Dry skin can make the itch worse, so using liberal amounts of moisturizer is useful if you have dry skin.
c) Do not scratch as scratching will generally make it worse. If scratching is irresistible it may help to rub the itchy area with an ice cube.

Fact Box

Chemical Class

Dihydroxy bile acids, alcohols and derivatives

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Hepatoprotectives

Interaction with drugs

Taking Obenow with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Theophylline (Oral Route) Moderate

Obeticholic acid may raise blood levels of Theophylline. watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may ... More

Cholestyramine (Oral Route) Moderate

Cholestyramine may reduce the efficacy of Obeticholic acid. To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Cholestyramine.

Tizanidine (Oral Route) Moderate

Obeticholic acid may raise blood levels of Tizanidine. watch out for symptoms of Tizanidine side effects such as breathlessness, fatigue, drowsiness, sedation or faintness or vomi... More

Warfarin (Oral Route) Moderate

Obeticholic acid may raise blood levels of Warfarin. Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly.

Colesevelam (Oral Route) Moderate

Colesevelam may reduce the efficacy of Obeticholic acid. To take Obeticholic acid, ensure a gap of at least 6 hours before or after taking Colesevelam.

View all drug interactions

Patient concerns

Suffering from chronic liver parenchymal disease since last three months is it curable and what food habit will follow?

Dr. Sfurti Mann

Internal Medicine

Liver cirrhosis can not be cured. Cause of liver cirrhosis needs to be worked up as well as upper GI endoscopy to look for varies. Avoid alcohol & pain killers .

attached is the report these are the medicines I've been taking: 1.udiplus 2.lecithin capsules - essential l 3.liv 52 ds since the last 10 days, the ggtp level is not going down from this level (84). what could be the reason?? is there any way or medicine to get it low?

Dr. Sfurti Mann

Internal Medicine

Alcohol can be a reasonOr obstruction in the biliary pathway

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Obeticholic acid [FDA Label]. New York, NY: Intercept Pharmaceuticals, Inc.; 2016. [Accessed 30 Jun. 2020]. (online) Available from:
Obeticholic Acid [Package Infirmation Sheet]. Haridwar, Uttarakhand: Akums Drugs & Pharmaceuticals Ltd.; 2020. [Accessed 20 Feb. 2024] (online) Available from:

Marketer details

Name: Lupin Ltd

Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.