Nusulta 375 Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 22 Feb 2026 | 06:32 PM (IST)

Nusulta 375 Tablet helps the body fight infections caused by bacteria. It is used to treat infections like upper respiratory tract infections, otitis media (ear infection), and tonsillitis. It also helps treat lower respiratory tract infections, including pneumonia, gonorrhea, and urinary tract infections.

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Saltum Tablet

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Nusulta 375 Tablet

strip of 10 tablets

₹393

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Same composition

Saltum Tablet

strip of 10 tablets

Sultamicillin tosilate (375mg)

by Morepen Laboratories Ltd

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General Information

Contains

Sultamicillin tosilate (375mg)

Marketer

Hawitt Pharmaceuticals Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Nusulta 375 Tablet may be taken with or without food. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it.

The dose will depend on what you are being treated for, but you should always complete a full course of Nusulta 375 Tablet as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive, and the infection may come back.

The most common side effects of this medicine include rash, vomiting, and diarrhea. These are usually mild, but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics or have any kidney or liver problems. This medicine is generally regarded as safe to use during pregnancy and breastfeeding if prescribed by a doctor.

Uses of Nusulta Tablet

Treatment of Bacterial infections

Benefits of Nusulta Tablet

Treatment of Bacterial infections
Nusulta 375 Tablet is an antibiotic medicine used for bacterial infections of the urinary tract and ear (otitis media) and gonorrhea. It stops the growth of infection-causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor; doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Nusulta Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nusulta

Vomiting
Diarrhea
Rash
Itching
Enterocolitis
Agranulocytosis (deficiency of granulocytes in the blood)

How to use Nusulta Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nusulta 375 Tablet may be taken with or without food.

How Nusulta Tablet works

Nusulta 375 Tablet is a combination of two medicines: ampicillin and sulbactam. Ampicillin kills bacteria by preventing them from building a protective cell wall, which is essential for their survival. Sulbactam helps by blocking bacterial enzymes that can make some bacteria resistant to ampicillin. This combination makes the antibiotic more effective in treating infections like respiratory, urinary, and skin infections.

All substitutes for Nusulta 375 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
Diarrhea may occur as a side effect, but it should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Discontinue Nusulta 375 Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of your face and mouth, or difficulty breathing.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nusulta 375 Tablet. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Nusulta 375 Tablet is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.

Breast feeding

CONSULT YOUR DOCTOR

Nusulta 375 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Nusulta 375 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CAUTION

Nusulta 375 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Nusulta 375 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Nusulta with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Sultamicillin tosilate. Please consult your doctor. Sultamicillin tosilate may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Sultamicillin tosilate may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Sultamicillin tosilate may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Amikacin (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Kanamycin (Injection Route)

Let your doctor know if you have a history of kidney disease. Your doctor may monitor your kidney function regularly.

Moderate

Streptomycin (Injection Route)

Let your doctor know if you have a history of kidney disease. Your doctor may monitor your kidney function regularly.

Frequently asked questions

Is Nusulta 375 Tablet safe?

Nusulta 375 Tablet is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

What if I forget to take a dose of Nusulta 375 Tablet?

If you forget a dose of Nusulta 375 Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next scheduled dose in the prescribed time. Do not double the dose to make up for the missed one, as this may increase the chances of developing side effects.

Can the use of Nusulta 375 Tablet cause diarrhea?

Yes, the use of Nusulta 375 Tablet can cause diarrhea. It is an antibiotic that kills the harmful bacteria. However, it can also affect the helpful bacteria in your stomach or intestine and cause diarrhea. If you experience severe diarrhea, inform your doctor about it.

Can I stop taking Nusulta 375 Tablet when I feel better?

No, do not stop taking Nusulta 375 Tablet without talking to your doctor, even if you feel better. Your symptoms may improve before the infection is completely cured. If you stop using Nusulta 375 Tablet too early, the symptoms may return or worsen. Continue taking Nusulta 375 Tablet in the dose and duration advised by the doctor.

Who should not use Nusulta 375 Tablet?

Use of Nusulta 375 Tablet should be avoided in patients who are allergic to Nusulta 375 Tablet or any of its components. However, if you are not aware of any allergy or if you are using Nusulta 375 Tablet for the first time, consult your doctor.

Fact Box

Chemical Class

Penicillins

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Ampicillin & Sulbactam ester compound

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hawitt Pharmaceuticals Pvt Ltd
Address: A-804, S3 Lifestyle Apartments, Pimple Saudagar, Pune -411027, Maharashtra (India)

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Nusulta 375 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Nusulta Tablet

Benefits of Nusulta Tablet

Side effects of Nusulta Tablet

How to use Nusulta Tablet

How Nusulta Tablet works

All substitutes for Nusulta 375 Tablet

Bactomin 375 Tablet

Marzon Tablet

Recontrex Tablet

Saltum Tablet

Sultalact 375mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Amikacin (Injection Route)

Kanamycin (Injection Route)

Streptomycin (Injection Route)

Frequently asked questions

Is Nusulta 375 Tablet safe?

What if I forget to take a dose of Nusulta 375 Tablet?

Can the use of Nusulta 375 Tablet cause diarrhea?

Can I stop taking Nusulta 375 Tablet when I feel better?

Who should not use Nusulta 375 Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests