Nugine 0.125mg Tablet is a medicine used to control bleeding from the uterus, that may occur after childbirth or an abortion. It works on the smooth muscle of the uterus and increases tone, rate, and amplitude of contractions thus reduces blood loss.

Nugine 0.125mg Tablet can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include headache, increase in blood pressure and seizure. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. Generally, alcohol should be avoided while taking this medicine.

Before taking this medicine, let your doctor know if you have ever had heart disease or you have high blood pressure. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.

Uses of Nugine Tablet

Post-delivery bleeding
Induction of labour

Benefits of Nugine Tablet

In Post-delivery bleeding

Nugine 0.125mg Tablet helps control excessive bleeding after childbirth by tightening the muscles of the uterus. This reduces blood loss and supports a quicker recovery, ensuring the mother's safety and well-being after delivery.

Side effects of Nugine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Nugine

High blood pressure
Headache
Seizure

How to use Nugine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nugine 0.125mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Nugine Tablet works

Nugine 0.125mg Tablet is an ergot alkaloid. It works by causing sustained contractions of the smooth muscles of the uterus. This results in compression of the blood vessels which controls bleeding after delivery.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Nugine 0.125mg Tablet. Please consult your doctor.

Pregnancy

UNSAFE

Nugine 0.125mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CAUTION

Nugine 0.125mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.

Driving

CONSULT YOUR DOCTOR

It is not known whether Nugine 0.125mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

CONSULT YOUR DOCTOR

There is limited information available on the use of Nugine 0.125mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited information available on the use of Nugine 0.125mg Tablet in patients with liver disease. Please consult your doctor.

What if you forget to take Nugine Tablet?

If you miss a dose of Nugine 0.125mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n \n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Nugine 0.125mg Tablet

₹6.31/Tablet

Methergin Tablet

Dr Reddy's Laboratories Ltd

₹9.02/tablet

43% costlier

Utergin 0.125mg Tablet

Maneesh Pharmaceuticals Ltd

₹9.02/tablet

43% costlier

Ergolin 0.125mg Tablet

Lincoln Pharmaceuticals Ltd

₹7.14/tablet

13% costlier

Mergin 0.125mg Tablet

Shrinivas Gujarat Laboratories Pvt Ltd

₹7.37/tablet

17% costlier

Gotrin 0.125mg Tablet

Rekvina Laboratories Ltd

₹4.46/tablet

29% cheaper

View all substitutes

Quick tips

Nugine 0.125mg Tablet is used for the prevention and control of post-delivery bleeding.
It may also be used for the active management of the third stage of labor, to facilitate the delivery of the placenta.
It should be avoided in patients, with high blood pressure, and heart disease.

Fact Box

Chemical Class

Ergolines

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Uterotonics & Abortificients

Interaction with drugs

Taking Nugine with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Ketoconazole (Injection Route) Life-threatening

Do not consume Methylergometrine with Ketoconazole. Ketoconazole may raise blood levels of Methylergometrine. Concurrent use may cause gangrene of fingers and toes.

Itraconazole (Oral Route) Life-threatening

Do not consume Methylergometrine with Itraconazole. Itraconazole may raise blood levels of Methylergometrine. Concurrent use may cause gangrene of fingers and toes.

Ketoconazole (Oral Route) Life-threatening

Do not consume Methylergometrine with Ketoconazole. Ketoconazole may raise blood levels of Methylergometrine. Concurrent use may cause gangrene of fingers and toes.

Clarithromycin (Oral Route) Severe

Do not consume Methylergometrine with Clarithromycin. Concurrent use may cause gangrene of fingers and toes.

Clarithromycin (Injection Route) Severe

Do not consume Methylergometrine with Clarithromycin. Concurrent use may cause gangrene of fingers and toes.

View all drug interactions

Patient concerns

I am pregnant.the doctor's date was 06.12.2016.but till now labour pain is not being occured.pls give the proper suggestions

Dr. Sonu Balhara Ahlawat

Obstetrics and Gynaecology

Go for induction of labour

Madam , after doing color dopler usg and bpp(report attached),my doc.is rocommending me to take castor oil.and telling aminic fluid is just adequate.So pl suggest upto which date we can wait for normal delivery.

Dr. Suman Rao

Obstetrics and Gynaecology

They have mentioned compromised maternal fetal circulation. If you have completed 9 weeks then better to go for induction of labour.

Right side of entire stomach and vegina lip and back side of spine heavy pain. Post delivery, C-Section. Also heavy bleeding through motion

Dr. Megha Tuli

Obstetrics and Gynaecology

Please visit an orthopedician regarding the pain. The pain could be due to a faulty spinal anaesthesia of a spinal issue. It is unrelated to the C section. For the bleeding, take plenty of fiber rich diet and lots of water. You can also take Syrup cremation 3 sf at night for a week

Should Nugine 0.125mg Tablet be taken with or without food?

Take Nugine 0.125mg Tablet orally with or without food as directed by your doctor, usually 3 to 4 times daily for up to 1 week after delivery. Dosage is based on your medical condition and response to treatment. Always follow your doctor's advice while taking Nugine 0.125mg Tablet.

Who should not take Nugine 0.125mg Tablet?

Nugine 0.125mg Tablet should not be taken by individuals who have a history of high blood pressure, heart disease, liver disease, kidney disease, or a history of seizures. It should also not be taken by pregnant women, as it can cause contractions of the uterus.

Can Nugine 0.125mg Tablet be used during breastfeeding?

Nugine 0.125mg Tablet can pass into breast milk and may harm a nursing infant. It is recommended to wait at least 12 hours after taking Nugine 0.125mg Tablet before breastfeeding.

Does Nugine 0.125mg Tablet increase blood pressure?

Yes, one of the most common adverse effects of Nugine 0.125mg Tablet is hypertension along with seizure. Seek immediate medical help in such a case.

Can Nugine 0.125mg Tablet be given to patients with heart disease?

Patients with risk factors for coronary artery disease (e.g., smoking, obesity, diabetes, high cholesterol) if administered Nugine 0.125mg Tablet, are more susceptible to heart blockage leading to severe complications.

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References

Methylergometrine. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2012. [Accessed 03 Apr. 2019] (online) Available from:

Marketer details

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Country of origin: India

The list of available options shown with the same composition has been prepared upon the advice of registered medical practitioners, pharmacists affiliated with TATA 1MG. TATA 1MG does not promote any pharmaceutical product of any particular company, and all recommendations are based on the medical opinion, advisories from specialist medical and pharmaceutical professionals.