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MMST, MBBS
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MD (Pharmacology), MBBS
Last updated on:
20 Aug 2019 | 05:00 PM (IST)
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Noxitef TZ 400mg/600mg Tablet


Overview

Introduction

Noxitef TZ 400mg/600mg Tablet is a combination of two antibiotics that effectively treats diarrhea and dysentery. It kills the microorganisms to treat the infection.

Noxitef TZ 400mg/600mg Tablet is a prescription medicine that can be taken with or without food. Take the medicine in the dose and duration advised by your doctor. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better.

Noxitef TZ 400mg/600mg Tablet may lead to some side effects such as nausea, dryness of mouth, stomach upset, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. In cases of severe liver or kidney disease it is advised to consult your doctor before you start with the treatment. It is strictly advised not to drive or operate heavy machinery while you are on the treatment.

Uses of Noxitef TZ Tablet

Noxitef TZ Tablet side effects

Common
  • Nausea
  • Dryness in mouth
  • Metallic taste
  • Headache

How to use Noxitef TZ Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Noxitef TZ 400mg/600mg Tablet is to be taken with food.
Taking it empty stomach can cause stomach upset.

How Noxitef TZ Tablet works

Noxitef TZ 400mg/600mg Tablet is a combination of two antibiotics: Norfloxacin and Tinidazole. Norfloxacin works by preventing the bacterial cells from dividing and repairing, thereby killing the bacteria. Tinidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, they treat your infection effectively.

Noxitef TZ Tablet related warnings

Alcohol
UNSAFE
Consuming alcohol while taking Noxitef TZ 400mg/600mg Tablet may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Noxitef TZ 400mg/600mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Noxitef TZ 400mg/600mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Noxitef TZ 400mg/600mg Tablet may cause side effects which could affect your ability to drive.
Noxitef TZ 400mg/600mg Tablet may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.
Kidney
CAUTION
Noxitef TZ 400mg/600mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Noxitef TZ 400mg/600mg Tablet may be needed. Please consult your doctor.
Use of Noxitef TZ 400mg/600mg Tablet is not advised in patients with severe kidney disease.
Liver
SAFE IF PRESCRIBED
Noxitef TZ 400mg/600mg Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Noxitef TZ 400mg/600mg Tablet may not be needed in these patients. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Noxitef TZ 400mg/600mg Tablet
₹3.62/Tablet
Nor-TZ Tablet
Alkem Laboratories Ltd
₹7/Tablet
93% costlier
Norflokem TZ Tablet
Alkem Laboratories Ltd
₹8.3/Tablet
129% costlier
₹7/Tablet
93% costlier
Matrix 400 mg/600 mg Tablet
Macleods Pharmaceuticals Pvt Ltd
₹10.5/Tablet
190% costlier
Fulstop 400 mg/600 mg Tablet
Adonis Laboratories Pvt Ltd
₹6.98/Tablet
93% costlier

Expert Advice

  • Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
  • Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you. 
  • Consult your doctor if your diarrhea lasts for more than 48 hours.
  • Do not use Noxitef TZ 400mg/600mg Tablet if you have blood in your stool or if you are severely constipated.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Noxitef TZ 400mg/600mg Tablet as it may irritate your stomach and also cause excessive drowsiness.
  • Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Patient Concerns

Questions Related to Noxitef TZ

arrow
Fever ; severe diarrhea & vomiting
Dr. Pushkar Mani
Diabetes Specialist
norflox tz twice daily for 3 days and paracetamol 500 mg thrice daily after food for 3 days and omez d 20mg twice daily for 5 days before foodalso give 2-3 sachets of electrol powder daily till 3-4 days
Sir dysentery problem. Taken norflox tz 3 doze + ors. Please help me out.
Dr. Pushkar Mani
Diabetes Specialist
u taking right medicine
arrow
Do you have any questions related to Noxitef TZ 400mg/600mg Tablet?

User Feedback


FAQs

Q. What is Noxitef TZ?

Noxitef TZ is a combination of two medicines: Norfloxacin and Tinidazole. This medication is used to treat diarrhea caused due to infection. They work by killing the harmful microorganisms that cause infection. Together they help to treat infection more effectively.

Q. Can I stop taking Noxitef TZ when my symptoms are relieved?

No, do not stop taking Noxitef TZ and complete the full course of treatment, even if you feel better. Your symptoms may improve before the infection is completely cured.

Q. Can Noxitef TZ increase the risk of tendon rupture?

Yes, Noxitef TZ is known to increase the risk of tendon rupture commonly in the achilles tendon. Tendon problems can happen in people of all ages who take Noxitef TZ. Inform your health care provider if you hear or feel a snap or pop, have severe pain, rapid or immediate bruising after an accident, and are unable to use the affected arm or leg. This may indicate that you have a tendon rupture.

Q. Can the use of Noxitef TZ cause metallic taste?

Yes, Noxitef TZ can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints, brushing teeth after the meals and by staying hydrated.

Q. Are there any specific contraindications associated with the use of Noxitef TZ?

The use of Noxitef TZ is considered to be harmful for patients with known allergy to norfloxacin or tinidazole or any other excipient present in the medicine. It should preferably be avoided in patients with a history of tendinitis (inflammation of the tendons) or tendon rupture caused because of the use of ciprofloxacin or any other medicine which belongs to the quinolone group of antimicrobial agents. It is also avoided in patients with some neurological disorders.

Q. Can I drink alcohol while taking Noxitef TZ?

No, avoid drinking alcohol while taking Noxitef TZ and for at least 3 days after the dosage is completed. Drinking alcohol while taking this medicine may cause an unpleasant reaction (Disulfuram like reaction) with symptoms such as stomach pain, nausea, vomiting, headache, flushing or redness of the face.

Q. Can I take ORS solution with Noxitef TZ?

Yes, you can take ORS (oral rehydration salts) with Noxitef TZ. ORS is a special combination of dry salts that is mixed with clean drinking water. It can help restore the fluids lost due to diarrhea. ORS packets or solution can be availed from the nearest pharmacy, shop or from our website.

Q. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Noxitef TZ can lead to increased side effects. Noxitef TZ takes time to show its full effect and treat your infection. If you are experiencing increased severity of diarrhea which is not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What is the recommended storage condition for Noxitef TZ?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. What if I don't get better after using Noxitef TZ?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Q. Can I stop taking Noxitef TZ when I feel better?

No, do not stop taking Noxitef TZ and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.

Q. What if I miss my dose?

Take Noxitef TZ as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Norfloxacin. Whitehouse Station, New Jersey: K MERCK & CO; 2008. [Accessed 15 Apr. 2019] (online) Available from:External Link
  2. Tinidazole. Atlanta, Georgia: Mikart Inc.; 2004 [revised May 2007]. [Accessed 15 Apr. 2019] (online) Available from:External Link
  3. ScienceDirect. Norfloxacin. [Accessed 15 Apr.] (online) Available from:External Link
  4. Tindazole. France: Fareva Amboise; 2016. [Accessed 15 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Leeford Healthcare Limited , Leo House, Shaheed Bhagat Singh Nagar, Dugri-Dhandra Road, Near Joseph School , Ludhiana-141116
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