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Nizonide-O Tablet is a combination medicine that is used to treat diarrhea and dysentery. It prevents the growth of microorganisms to treat the infection.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 02 Mar 2026 | 12:39 PM (IST)
₹113 MRP ₹125.0910% off 
As per Ministry of Health and Family Welfare
 
 
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General Information

The content is shown in English
Nizonide-O Tablet image
Nizonide-O Tablet image
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Nizonide-O Tablet image
Nizonide-O Tablet image
Nizonide-O Tablet image

Product introduction

Nizonide-O Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It should be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.

Nizonide-O Tablet may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.

Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.

Uses of Nizonide-O Tablet

Benefits of Nizonide-O Tablet

Diarrhea
Diarrhea is a condition marked by frequent, loose, or watery stools, often caused by infections, contaminated food or water, or digestive issues. If not treated, it can lead to dehydration, weakness, and disruption of daily activities. Nizonide-O Tablet helps treat the infection causing the diarrhea, reduces the frequency of loose stools, and supports faster recovery. It brings quick relief, restores digestive balance, and helps individuals regain strength and return to normal routines more comfortably.
Dysentery
Dysentery is a more severe form of intestinal infection that causes diarrhea with blood and mucus, along with abdominal cramps, fever, and weakness. If left untreated, it can lead to significant fluid loss and serious health complications. Nizonide-O Tablet targets the underlying infection, reduces inflammation, and helps stop the bloody diarrhea. This results in faster healing, less abdominal pain, and improved overall well-being, making recovery smoother and safer.

Side effects of Nizonide-O Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nizonide-O
  • Nausea
  • Vomiting
  • Stomach pain
  • Headache

How to use Nizonide-O Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nizonide-O Tablet may be taken with or without food.

How Nizonide-O Tablet works

Nizonide-O Tablet is a combination of two medicines: Nitazoxanide and Ofloxacin. Nitazoxanide is an antiparasitic. It works by interfering with the energy metabolism of parasites, which ultimately causes their death. Ofloxacin kills bacteria by preventing them from reproducing and repairing themselves. Together, they treat your infection effectively.

Quick tips

  • Take your medication timely to maintain steady levels in your body.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
  • Discontinue Nizonide-O Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • It is advisable to drink plenty of fluids and a healthy diet while taking the medicine.
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how medicine affects you.
  • Take your medication timely to maintain steady levels in your body.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
  • Discontinue Nizonide-O Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • It is advisable to drink plenty of fluids and a healthy diet while taking the medicine.
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how medicine affects you.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Nizonide-O Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Nizonide-O Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Nizonide-O Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Nizonide-O Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Nizonide-O Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Nizonide-O Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Inform your doctor about all your medical conditions and the medicines you are taking.
Nizonide-O Tablet contains ofloxacin, which can cause insomnia. Consult your doctor if you have a consistent sleeping problem while taking this medicine.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

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User feedback

Twice A Day
89%
Once A Day
10%
Thrice A Day
1%
Alternate Day
1%
Diarrhea
50%
Others
32%
Bacterial infections
11%
Worm infections
7%
Average
52%
Poor
33%
Excellent
14%
No Side Effect
43%
Headache
29%
Nausea
14%
Fever
14%
With food
50%
With or without food
25%
Empty stomach
25%
Average
47%
Not Expensive
33%
Expensive
20%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India
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