


Nicoflox TZ Tablet
Ofloxacin (200mg)+ Tinidazole (600mg)
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Nicoflox TZ Tablet is a combination medicine that is used to treat diarrhea and dysentery. It prevents the growth of microorganisms to treat the infection.
Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 Jun 2026 | 05:05 PM (IST)
Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 Jun 2026 | 05:05 PM (IST)
0

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Oflox TZ Tablet
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Nicoflox TZ Tablet
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₹21.7

Same composition
Oflox TZ Tablet
strip of 10 tablets
by Cipla Ltd
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₹87.5
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General Information
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Product introduction
Nicoflox TZ Tablet is a prescription medicine that is advised to be taken as suggested by the doctor. It should be taken with or without food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as an overdose of it may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better to ensure a complete recovery.
Nicoflox TZ Tablet may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.
Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.
Nicoflox TZ Tablet may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.
Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.
Benefits of Nicoflox TZ Tablet
Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Nicoflox TZ Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Nicoflox TZ Tablet helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.
Dysentery
Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Nicoflox TZ Tablet helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.
Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Nicoflox TZ Tablet helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.
Side effects of Nicoflox TZ Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nicoflox TZ
- Nausea
- Dryness in mouth
- Metallic taste
- Headache
How to use Nicoflox TZ Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Nicoflox TZ Tablet may be taken with or without food.
How Nicoflox TZ Tablet works
Nicoflox TZ Tablet is a combination of two antibiotics: Ofloxacin and Tinidazole. Ofloxacin works by preventing the bacterial cells from dividing and repairing, thereby killing the bacteria. Tinidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, they treat your infection effectively.
All substitutes for Nicoflox TZ Tablet
For information purposes only. Consult a doctor before taking any medicine.
Oflox TZ Tablet
by Cipla Ltd
₹10.3/tablet
375% costlier
Oflomac TZ 200 mg/600 mg Tablet
by Macleods Pharmaceuticals Pvt Ltd
₹10.7/tablet
393% costlier
Dto 200 mg/600 mg Tablet
by DWD Pharmaceuticals Ltd
₹6.11/tablet
182% costlier
Pin OT 200 mg/600 mg Tablet
by Medoz Pharmaceutical Pvt. Ltd
₹5.12/tablet
136% costlier
Oflavid-TZ 200mg/600mg Tablet
by Trigenesis Life Sciences Pvt Ltd
₹5.82/tablet
168% costlier
Quick tips
- Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
- Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you.
- Consult your doctor if your diarrhea lasts for more than 48 hours.
- Do not use Nicoflox TZ Tablet if you have blood in your stool or if you are severely constipated.
- It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
- Avoid consuming alcohol when taking Nicoflox TZ Tablet as it may irritate your stomach and also cause excessive drowsiness.
- Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Safety advice

Alcohol
UNSAFE
Consumption of alcohol with Nicoflox TZ Tablet may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.

Pregnancy
UNSAFE
Nicoflox TZ Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding
UNSAFE
Nicoflox TZ Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving
UNSAFE
Nicoflox TZ Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Nicoflox TZ Tablet may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.
Nicoflox TZ Tablet may make you feel drowsy or gives you problems with coordination or sensation (e.g. numbness or weakness). This may affect your driving ability.

Kidney
CAUTION
Nicoflox TZ Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Nicoflox TZ Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions
Yes, the use of Nicoflox TZ Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry.
Nicoflox TZ Tablet should be used with caution in nursing mothers as it can lead to serious side effects. You should always consult your doctor before taking Nicoflox TZ Tablet.
Yes, the use of Nicoflox TZ Tablet can cause a temporary metallic taste. This metallic taste can be reduced by chewing sugar-free gum or mints, brushing teeth after the meals and by staying hydrated.
No, taking a higher than the recommended dose of Nicoflox TZ Tablet can lead to increased side effects. If you are experiencing increased severity of your symptoms which are not relieved by the recommended doses, please consult your doctor for re-evaluation.
The use of Nicoflox TZ Tablet is considered to be harmful for patients with known allergy to ofloxacin or tinidazole or any other excipient. It should preferably be avoided in patients with a history of any inflammation of the tendons (tendinitis), or tendon rupture seen with the use of ofloxacin or any other medicine which belongs to the same group (quinolone group) of antimicrobial agents and in patients with some neurological disorders.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
No, do not stop taking Nicoflox TZ Tablet and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.
Take Nicoflox TZ Tablet as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
It is usually taken with or without food, twice a day, for 3 days to 6 weeks. The length of treatment depends on the type of infection being treated. Always consult the doctor before taking the medicine.
No, taking Nicoflox TZ Tablet may make you feel sleepy, dizzy and may lead to visual disturbances. So, do not drive or use machines while you are on this medicine.
Fact Box
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Related lab tests
References
- Rosenthal PJ. Antiprotozoal drugs. In: Katzung BG, Masters SB, Trevor AJ (Editors). Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 899-923.
- Phillips MA, Stanley, Jr SL. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1049-72.
- MacDougall C. Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1111-1126.
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- CBC (Complete Blood Count)
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- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
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