Neopred Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 01 Feb 2026 | 11:37 PM (IST)

Neopred Tablet is a type of antibiotic used to prevent infection before or after certain intestinal surgeries. It works by stopping the growth of bacteria in the intestines. This medicine is also used to treat a certain type of coma seen in patients with liver disease (hepatic encephalopathy).

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General Information

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The content is shown in English

Product introduction

Neopred Tablet should be taken orally, as per the dosage and schedule prescribed by your doctor. It may be taken with or without food. Use this medicine regularly to derive maximum benefit from it. Do not skip any doses and finish the full course of treatment even if you feel better.

Commonly seen side effects seen with this medicine include diarrhea, nausea, and vomiting. These are usually temporary and subside with the completion of treatment. Consult your doctor if you find these side effects bother or worry you.

Before taking this medicine, inform your doctor if you have any previous history of allergy to it or any other medicine in the past. Pregnant or breastfeeding women should consult their doctor before using this medicine.

Uses of Neopred Tablet

Bacterial infections
Hepatic encephalopathy

Benefits of Neopred Tablet

Bacterial infections
Neopred Tablet is an antibiotic which works by stopping the growth of infection causing bacteria on your skin. It prevents the synthesis of essential proteins necessary for survival of bacteria. It is effective against skin infections such as boils, impetigo and infected hair follicles. It may also be used to treat infections in small cuts or wounds on your skin. This treatment has few common side effects and should clear up infections within a few days, but you should keep using it for as long as it is prescribed.

Hepatic encephalopathy
Hepatic encephalopathy is a severe liver disease that can cause changes in brain function leading to confusion, tremors (shaking), sleep problems and loss of consciousness. Neopred Tablet lowers the levels of ammonia-producing bacteria in the blood which has harmful effects on the brain. If taken as prescribed, this medicine can improve your brain function and reduce the symptoms associated with hepatic encephalopathy.

Side effects of Neopred Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neopred

Diarrhea
Nausea
Vomiting

How to use Neopred Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neopred Tablet may be taken with or without food.

How Neopred Tablet works

Neopred Tablet is an antibiotic. It works in liver disease by killing the ammonia-producing bacteria. The liver normally breaks down ammonia, but in liver disease this function may be impaired, allowing it to enter the brain. Neopred Tablet prevents this by affecting bacteria's production of certain proteins that are necessary for their survival. This ultimately kills the bacteria and treats the infection.

Quick tips

Neopred Tablet is used to sterilise the bowel before surgery.
It may also be used to prevent impairment of brain function in severe liver disease.
Your doctor may regularly monitor your kidney function and your hearing while you are taking this medicine.
Inform your doctor if you experience any hearing loss, ringing sensation, dizziness or unsteadiness during treatment.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Neopred Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Neopred Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Neopred Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

NOT RELEVANT

Not relevant, as Neopred Tablet is intended for use in hospitalized patients.

Kidney

CAUTION

Neopred Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Neopred Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Neopred with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Neomycin. Please consult your doctor. Neomycin may reduce the efficacy of Cholera Vaccine (Inactivated).

Severe

Sorafenib (Oral Route)

Neomycin may reduce blood levels and efficacy of Sorafenib. Neomycin may reduce blood levels and efficacy of Sorafenib.

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Neomycin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Neomycin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Moderate

Pyridostigmine (Oral Route)

Your doctor may monitor the effects of Pyridostigmine along with your overall treatment and adjust the doses as per the observations. Neomycin may block the action of Pyridostigmine.

Moderate

Digoxin (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Neomycin may reduce the efficacy of Digoxin.

Frequently asked questions

What is Neopred Tablet used for?

Neopred Tablet is mainly used to reduce harmful bacteria in the intestines, especially before certain bowel surgeries. It may also be used in people with hepatic coma (a serious liver-related condition) to help lower the level of toxins produced by gut bacteria.

Is Neopred Tablet an antibiotic?

Yes. Neopred Tablet is an oral antibiotic that helps decrease certain bacteria in the gut. It is not used for colds, flu, or other viral infections.

Why is Neopred Tablet considered a high-risk antibiotic?

Neopred Tablet can sometimes be absorbed into the body and cause serious side effects such as kidney damage, hearing problems, or nerve issues. Because of these risks, doctors use it only when clearly needed and monitor patients carefully.

Who should not take Neopred Tablet?

Neopred Tablet should be avoided by individuals who have intestinal obstruction, inflammatory, or ulcerative gut diseases (because this increases absorption and risk of toxicity), are allergic to neomycin or any other aminoglycoside antibiotic, or have had previous serious reactions to drugs in this antibiotic group.

Can Neopred Tablet cause permanent hearing loss?

Yes. Neopred Tablet carries a risk of permanent hearing damage, sometimes even after you stop taking the medicine. This risk is higher if you have kidney problems, are elderly, dehydrated, or are taking other drugs that affect hearing.

What are the serious side effects of Neopred Tablet?

Serious side effects of Neopred Tablet include ringing in the ears, difficulty hearing, balance problems, muscle weakness, twitching, unusual numbness, reduced urination, severe nausea, vomiting, or persistent diarrhea. Seek immediate medical attention if you experience any of these symptoms.

Is Neopred Tablet safe for children?

Neopred Tablet is not proven safe or effective for people under 18 years of age. If used in children, it must be with extreme caution, and for a very short duration.

Can Neopred Tablet worsen muscle weakness?

Yes. Neopred Tablet can make muscle-related conditions worse, especially if you have myasthenia gravis or Parkinson’s disease, because it may affect nerve-muscle communication.

Why do doctors limit the duration of Neopred Tablet?

Neopred Tablet becomes riskier the longer you take it. To reduce risks of kidney damage, hearing loss, and nerve problems, doctors use the lowest effective dose for the shortest possible time, usually not longer than two weeks.

Fact Box

Chemical Class

Aminoglycosides

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Bacterial Protein Synthesis Inhibitors- Aminoglycosides

Related lab tests

Ammonia

Complete Blood Count

Liver Function Test

Peripheral Smear Examination

Potassium

Sodium

References

MacDougall C, Chambers HF. Aminoglycosides. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1518.
Chambers HF, Deck DH. Aminoglycosides & Spectinomycin. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 813.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 968.
ScienceDirect. Neomycin. [Accessed 31 Mar. 2019] (online) Available from:
PubChem. Neomycin. [Accessed 31 Mar. 2019] (online) Available from:
Colistin sulfate—neomycin sulfate—thonzonium bromide—hydrocortisone acetate otic suspension. Rochester, MI: JHP Pharmaceuticals, LLC; 2009. [Accessed 08 Apr. 2019] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hema Laboratories
Address: Plot No.: 6201/A, Opp. EWAC Alloys, GIDC, Ankleshwar - 393002, Gujarat, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

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Neopred Tablet

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Neopred Tablet

Benefits of Neopred Tablet

Side effects of Neopred Tablet

How to use Neopred Tablet

How Neopred Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Sorafenib (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Pyridostigmine (Oral Route)

Digoxin (Oral Route)

Frequently asked questions

What is Neopred Tablet used for?

Is Neopred Tablet an antibiotic?

Why is Neopred Tablet considered a high-risk antibiotic?

Who should not take Neopred Tablet?

Can Neopred Tablet cause permanent hearing loss?

What are the serious side effects of Neopred Tablet?

Is Neopred Tablet safe for children?

Can Neopred Tablet worsen muscle weakness?

Why do doctors limit the duration of Neopred Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Ammonia

Complete Blood Count

Liver Function Test

Peripheral Smear Examination

Potassium

Sodium

References

User feedback

How much was the improvement?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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