Neocalm 5mg Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 07 Apr 2026 | 02:54 PM (IST)

Neocalm 5mg Tablet is used in the treatment of schizophrenia. It may also be used for the short term to treat anxiety when other medications have not worked. It alters the thoughts and elevates the mood, improving the person’s ability to think, feel, and behave.

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General Information

Contains

Trifluoperazine (5mg)

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Neocalm 5mg Tablet should be taken with or without food. Take it at the same time each day, as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor, and if you have missed a dose, take it as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Finish the full course of treatment even if you feel better. This medication must not be stopped suddenly without talking to your doctor, as it may worsen your symptoms.

Some common side effects of this medicine include dry mouth, dizziness, skin reactions, insomnia, and muscular weakness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions. Rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, or allergy medication. This medicine can also lead to weight gain. Eat a healthy, balanced diet, avoid snacking on high-calorie food, and exercise regularly.

Uses of Neocalm Tablet

Benefits of Neocalm Tablet

Short term anxiety
Neocalm 5mg Tablet reduces the symptoms of excessive anxiety and worry that are triggered only at the time of stressful conditions that last for a shorter duration. These could be job interviews, exams, stage performances, etc. It can effectively manage feelings of restlessness, tiredness, difficulty concentrating and feeling irritable. Neocalm 5mg Tablet will therefore help you go about your daily activities more easily and be more productive. Keep taking this medicine even if you feel well. Stopping suddenly can cause serious problems.

Treatment of Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Neocalm 5mg Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to as it can worsen your condition.

Side effects of Neocalm Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Neocalm

Skin reaction

How to use Neocalm Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Neocalm 5mg Tablet may be taken with or without food.

How Neocalm Tablet works

Neocalm 5mg Tablet is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Inhibiting dopamine receptors helps restore neurotransmitter balance, making it effective in managing schizophrenia, anxiety, and other mood disorders. This action helps reduce symptoms such as hallucinations, delusions, and disorganized thinking, improving overall mental stability.

All substitutes for Neocalm 5mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take Neocalm 5mg Tablet at bedtime to avoid feeling sleepy during the day.
Use caution while driving or doing anything that requires concentration, as Neocalm 5mg Tablet can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid drinking alcohol while taking this medicine, as it can cause increased sedation.
It may increase your blood sugar and cholesterol levels. Eat healthy, exercise regularly, and monitor your blood levels regularly.
Don't stop taking Neocalm 5mg Tablet without talking to your doctor first, as it may cause worsening of symptoms.
You have been prescribed Neocalm 5mg Tablet for the treatment of schizophrenia.
It may cause less weight gain as compared to other similar medicines.
Take it at bedtime to avoid feeling sleepy during the day.
Use caution while driving or doing anything that requires concentration as Neocalm 5mg Tablet can cause dizziness and sleepiness.
To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
Avoid drinking alcohol while taking this medicine as it can cause increased sedation.
Inform your doctor if you experience abnormal movements, particularly of the face, lips, jaw and tongue, while taking this medicine.
It may increase your blood sugar and cholesterol level. Eat healthy, exercise regularly and monitor your blood levels regularly.
Don't stop taking Neocalm 5mg Tablet without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Neocalm 5mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

Neocalm 5mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Neocalm 5mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Neocalm 5mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Neocalm 5mg Tablet make u feel dizzy, drowsy, or can cause blurred vision. This may affect your driving ability.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Neocalm 5mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Neocalm 5mg Tablet in patients with liver disease.

Interaction with drugs

Taking Neocalm with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Iopamidol (Injection Route)

Do not consume Trifluoperazine 48 hours before and At least 12 hours after consuming Iopamidol.

Life-threatening

Iohexol (Injection Route)

Do not consume Trifluoperazine 48 hours before and At least 24 hours after consuming Iohexol.

Severe

Moxifloxacin (Oral Route)

Do not consume Moxifloxacin with Trifluoperazine. If concurrent use is essential, watch out for symptoms such as muscle spasms, tremors, tiredness, nausea, reduced appetite, palpitations, or numbness. Your doctor may monitor your heart functioning regularly.

Severe

Lithium carbonate (Oral Route)

If concurrent use is essential, watch out for symptoms such as double vision, weakness, dizziness, impaired coordination, or confusion and consult your doctor if you experience them. Your doctor may monitor your ECG frequently and discontinue the medicines if required. Lithium carbonate may reduce blood levels of active form of Trifluoperazine.

Severe

Moxifloxacin (Injection Route)

Frequently asked questions

What is Neocalm 5mg Tablet used for?

Neocalm 5mg Tablet is mainly used to treat schizophrenia (a mental illness that affects thinking and behavior) and can also be used short-term for severe anxiety when other treatments haven’t worked.

Can Neocalm 5mg Tablet be used in elderly people with memory problems or dementia?

No, Neocalm 5mg Tablet should not be used in elderly patients with dementia-related psychosis, as it can increase the risk of stroke or death. Always consult your doctor for a safer and better treatment regimen.

What are the most serious side effects of Neocalm 5mg Tablet?

The serious side effects of Neocalm 5mg Tablet include tardive dyskinesia (uncontrollable facial and body movements), neuroleptic malignant syndrome (fever, stiff muscles, confusion), low white blood cell counts (increased risk of infections), risk of seizures or their worsening, and liver problems or jaundice. If you notice symptoms like fever, stiff muscles, confusion, or yellowing of skin or eyes, seek medical help immediately.

Can Neocalm 5mg Tablet cause movement problems?

Yes. Neocalm 5mg Tablet can cause tremors, muscle stiffness, restlessness, or uncontrollable movements. These effects may be temporary or permanent, especially with long-term use.

How long does Neocalm 5mg Tablet take to work?

You may notice some calming effects within hours after taking Neocalm 5mg Tablet, but full therapeutic benefits for psychotic symptoms typically take a few weeks of consistent use. Continue taking as directed by your doctor, even if you feel immediate symptom relief.

Can Neocalm 5mg Tablet cause weight gain?

Unlike newer antipsychotic medicines, Neocalm 5mg Tablet is less likely to cause significant weight gain. However, some patients may experience mild appetite changes. Monitor your weight and discuss any concerns with your doctor.

Is it safe to drink alcohol while taking Neocalm 5mg Tablet?

Alcohol should be avoided with Neocalm 5mg Tablet as it can increase drowsiness and dizziness. Combining alcohol with Neocalm 5mg Tablet may also worsen side effects and reduce the medication's effectiveness.

When should I stop taking Neocalm 5mg Tablet?

Never stop Neocalm 5mg Tablet abruptly. Your doctor will create a gradual tapering schedule to avoid withdrawal symptoms like nausea, vomiting, dizziness, or return of psychotic symptoms. Follow their instructions carefully.

Can Neocalm 5mg Tablet cause addiction?

Neocalm 5mg Tablet is not considered addictive, but stopping suddenly after long-term use can cause withdrawal symptoms. Always follow your doctor's instructions for discontinuing the medication.

Fact Box

Chemical Class

Phenothiazines

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Typical Antipsychotics

References

Stahl SM, editor. Trifluoperazine. In: Stahl's Essential Psychopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 691-95.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 1404.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Trifluoperazine. [Updated 2018 Oct 31]. [Accessed 20 Feb. 2020] (online) Available from:
Trifluoperazine [EMC Label]. Leeds, Yorkshire: Rosemont Pharmaceuticals Limited; 2018. [Accessed 19 Mar. 2019] (online) Available from:
Trifluoperazine. Vaughan, Ontario; 2014 [revised 27 Nov. 2018]. [Accessed 05 Feb. 2025] (online) Available from:
Trifluoperazine [Medication Information Leaflet]. 2021. [Accessed 05 Feb. 2025] (online) Available from:
Trifluoperazine [Prescribing Information]. Morgantown, WV: Mylan Pharmaceuticals Inc.; 2024. [Accessed 05 Feb. 2025] (online) Available from:

User feedback

Patients taking Neocalm 5mg Tablet

Once A Day

50%

Twice A Day

25%

Alternate Day

12%

Thrice A Day

12%

What are you using Neocalm Tablet for?

Anxiety disorder

100%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Neocalm 5mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Neocalm Tablet

Benefits of Neocalm Tablet

Side effects of Neocalm Tablet

How to use Neocalm Tablet

How Neocalm Tablet works

All substitutes for Neocalm 5mg Tablet

Talecalm 5mg Tablet

Schizonil 5mg Tablet

Gencalm 5mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Iopamidol (Injection Route)

Iohexol (Injection Route)

Moxifloxacin (Oral Route)

Lithium carbonate (Oral Route)

Moxifloxacin (Injection Route)

Frequently asked questions

What is Neocalm 5mg Tablet used for?

Can Neocalm 5mg Tablet be used in elderly people with memory problems or dementia?

What are the most serious side effects of Neocalm 5mg Tablet?

Can Neocalm 5mg Tablet cause movement problems?

How long does Neocalm 5mg Tablet take to work?

Can Neocalm 5mg Tablet cause weight gain?

Is it safe to drink alcohol while taking Neocalm 5mg Tablet?

When should I stop taking Neocalm 5mg Tablet?

Can Neocalm 5mg Tablet cause addiction?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Neocalm 5mg Tablet

What are you using Neocalm Tablet for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

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