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Last updated:
18 Feb 2020 | 05:25 PM (IST)
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Natclovir 250mg Injection

Prescription Required
Manufacturer
SALT COMPOSITION

Overview

Introduction

Natclovir 250mg Injection is an antiviral medicine used to treat viral infections caused by cytomegalovirus in immunocompromised people who have undergone an organ or bone marrow transplantation. It also reduces the risk of blindness in a serious eye infection caused by CMV, known as CMV retinitis.

Natclovir 250mg Injection is administered as an injection by a healthcare professional. Kindly do not self administer. It is given by slow intravenous (I.V.) infusion over a 1-hour period to avoid damage to kidneys. You should drink plenty of water while on treatment with this medicine as it helps to prevent dehydration and kidney damage.

Some side effects include vomiting, nausea, and increased liver enzymes. You may also notice some injection site reactions like pain, swelling or redness. Inform your doctor if these side effects persist for a longer duration. Please consult your doctor if you are pregnant, planning to conceive or breastfeeding.

Uses of Natclovir Injection

  • Cytomegalovirus Infection

Side effects of Natclovir Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Natclovir

  • Vomiting
  • Nausea
  • Injection site reaction
  • Increased liver enzymes

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Injection site reaction
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.
  • Coping with Increased liver enzymes
    There may be no symptoms, so your doctor should carry out a blood test and give you advice. Some lifestyle changes can bring down levels of liver enzymes. In general, you will need to stop drinking alcohol or limit the amount you drink, lose weight and keep active. Drink plenty of fluids to avoid dehydration. Eat a healthy diet. Some particular foods like nuts, fatty fish, coffee, tea, olive oil, sprouts and bananas may be beneficial. Try to control stress as this can make your symptoms worse.

How to use Natclovir Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Natclovir Injection works

Natclovir 250mg Injection is an antiviral medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Natclovir 250mg Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Natclovir 250mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Natclovir 250mg Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Natclovir 250mg Injection may cause side effects which could affect your ability to drive.
You may feel sleepy, dizzy, confused or shaky, or you may lose your balance or have fits while using Natclovir 250mg Injection.
Kidney
CAUTION
Natclovir 250mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Natclovir 250mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test and some blood tests may be advised while you are taking this medicine.
Liver
CAUTION
Natclovir 250mg Injection should be used with caution in patients with liver disease. Dose adjustment of Natclovir 250mg Injection may be needed. Please consult your doctor.

What if you forget to take Natclovir Injection?

If you miss a dose of Natclovir 250mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Fact Box

Chemical Class
Nucleoside analog
Habit Forming
No

Interaction with Drugs

Taking Natclovir with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Abamune, A-Bec, Virol
LIFE-THREATENING
Brand(s): Adesera, Adheb, Adfovir
LIFE-THREATENING
Brand(s): Dinex EC, Dinosin, Virosine DR
LIFE-THREATENING
Brand(s): Entehep
LIFE-THREATENING

Patient Concerns

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I got my body tests done and found testosterone below the minimum range. Please advice.
Dr. Vinod Raina
Sexology
Take inj sustonone 250mg depot once a month
PATIENT of 36 days. Left eye is feeling like having conjunctivitis infection. Yellow excretion is started which eye drop should be given.
Dr. Richa Jain
Ophthalmology
If there is heavy infection. . Antibiotic injection shd be given. Visit for examination
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Do you have any questions related to Natclovir 250mg Injection ?

FAQs

Q. Is Natclovir a vesicant/ antibiotic?

No, Natclovir is not a vesicant/ an antibiotic

Q. Is Natclovir?

Yes, Natclovir is dialyzabl

Q. Is Natclovir a chemotherapy drug?

Yes, Natclovir is a chemotherapy used for the treatment of viral infections. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer

Q. Is Natclovir nephrotoxic?

Yes, Natclovir is known to have nephrotoxicity (toxic to kidneys)

Q. Is ganciclovir a protease inhibitor?

No, ganciclovir is not a protease inhibitor; it belongs to synthetic nucleoside analogues class of antivirals

Q. Does Natclovir cover hsv (hepes simplex virus)?

Yes, Natclovir may be used to treat hsv (hepes simplex virus)

Q. How does Natclovir cause myelosuppression?

Natclovir is directly toxic to colony forming stem cells inside bone marrow which is responsible for RBCs, WBCs and platelets formation, thereby causing myelosuppression.

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Acosta EP, Flexner C. Antiviral Agents (Nonretroviral). In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1603-605.
  2. Safrin S. Antiviral Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 851-52.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 613-14.
  4. Ganciclovir sodium. Garden City, Hertfordshire: Roche Products Limited; 1988 [revised 16 May 2018]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. Medscape. Ganciclovir. [Accessed 01 Apr. 2019] (online) Available from:External Link
  6. Ganciclovir. Nutley, New Jersey: Roche Pharmaceuticals. [Accessed 01 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
A licensed vendor partner from your nearest location will deliver Natclovir 250mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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₹1474.75
1 Injection in 1 vial
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