Naltrex 50mg Tablet

Naltrexone (50mg)

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Naltrex 50mg Tablet is used in the treatment of opioid dependence and alcohol addiction. It works by blocking the euphoric feelings (highs) that some people may experience after taking opiates and alcohol. This reduces the craving and helps you stay away from them.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 21 Jan 2026 | 04:44 PM (IST)

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General Information

Contains

Naltrexone (50mg)

Marketer

Synmedic Laboratories

Storage

Store below 30°C

The content is shown in English

Product introduction

Naltrex 50mg Tablet may be taken with or without food. Take it regularly at a fixed time each day to get the maximum benefit of the medicine. Continue taking the medicine for as long as the doctor has prescribed it. Do not stop taking the medicine until you have finished the full course.

Common side effects of this medicine include nausea, vomiting, headache, nervousness, anxiety, sleep disorders, restlessness, abdominal pain, joint pain, muscle pain, and weakness. Do not drive or operate machinery after taking the medicine, as you may feel dizzy or tired.

Uses of Naltrex Tablet

Benefits of Naltrex Tablet

Treatment of Opioid dependence
Opioids are prescribed to treat pain. With prolonged use, the body may become dependent on them and causing withdrawal symptoms, which makes it difficult to stop taking them. Naltrex 50mg Tablet helps prevent these cravings that lead to opioid dependence and also helps the person refrain from taking them repeatedly.

Treatment of Alcohol addiction
Naltrex 50mg Tablet is a medicine used, along with social support and counseling, to help people recover from alcohol addiction and to avoid having the urge to drink alcohol again. Naltrex 50mg Tablet starts working from the very first dose and is a very safe and effective way of treating alcohol addiction.

Side effects of Naltrex Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Naltrex

Joint pain
Muscle pain
Headache
Vomiting
Weakness
Nausea
Abdominal pain
Anxiety
Nervousness
Restlessness
Sleep disorder
Fatigue
Sleepiness

How to use Naltrex Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Naltrex 50mg Tablet may be taken with or without food.

How Naltrex Tablet works

Naltrex 50mg Tablet is an opioid antagonist. It works by blocking the euphoric feelings (highs) that you may experience after taking opiates and alcohol. This reduces craving and helps you remain off of them.

All substitutes for Naltrex 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it at the same time every day to help you remember to take it.
Do not consume opioid derivatives while on this treatment.
Do not drive or do anything requiring concentration until you know how Naltrex 50mg Tablet affects you.
Your doctor may check your liver function before starting treatment and regularly thereafter.
Inform your doctor if you are pregnant, planning to become pregnant or are breastfeeding.

Safety advice

Alcohol

SAFE

Consuming alcohol with Naltrex 50mg Tablet does not usually cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

Naltrex 50mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Naltrex 50mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Naltrex 50mg Tablet may cause side effects that could affect your ability to drive.
Naltrex 50mg Tablet may make you feel tired or dizzy. This may affect your driving ability.

Kidney

CAUTION

Naltrex 50mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Naltrex 50mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is advisable while you are taking this medicine.

Interaction with drugs

Taking Naltrex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Buprenorphine (Injection Route)

Do not consume Naltrexone with Buprenorphine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Buprenorphine.

Life-threatening

Buprenorphine (Oral Route)

Do not consume Naltrexone with Buprenorphine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Buprenorphine.

Life-threatening

Buprenorphine (Transdermal Route)

Do not consume Naltrexone with Buprenorphine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Buprenorphine.

Life-threatening

Buprenorphine (Sublingual route)

Do not consume Naltrexone with Buprenorphine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Buprenorphine.

Life-threatening

Butorphanol (Injection Route)

Do not consume Naltrexone with Butorphanol; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Butorphanol.

Frequently asked questions

Can you take Naltrex 50mg Tablet forever?

No, Naltrex 50mg Tablet must be taken as long as prescribed by your doctor

Does Naltrex 50mg Tablet make you high/ sleepy?

No, Naltrex 50mg Tablet does not make you high but, may rarely make you sleepy

Does Naltrex 50mg Tablet help with opiate cravings?

Yes, Naltrex 50mg Tablet helps reduce opiate cravings

Fact Box

Chemical Class

Phenanthrene derivative

Habit Forming

Therapeutic Class

NEURO CNS

Action Class

Opioid Antagonists

Related lab tests

Opiates

References

Schuckit MA. Ethanol and Methanol. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 642-43.
Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 547-48.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 953-54.
Central Drugs Standard Control Organisation (CDSCO). [Accessed 6 Apr. 2019] (online) Available from:
Naltrexone hydrochloride [Drug label]. Pomona, New York; Duramed Pharmaceuticals, Inc.; 2013. [Accessed 20 Feb. 2024] (online) Available from:
Naltrexone [Prescribing Information]. Auckland, New Zealand: Max Health Ltd.; 2020.

User feedback

What are you using Naltrex Tablet for?

Alcohol addiction

82%

Opioid dependence

18%

How much was the improvement?

Average

62%

Poor

29%

Excellent

What were the side-effects while using Naltrex 50mg Tablet?

Weakness

12%

Back pain

12%

Joint pain

12%

No Side Effect

12%

Muscle pain

12%

How do you take Naltrex Tablet?

With food

67%

With or without food

33%

Please rate Naltrex 50mg Tablet on price

Not Expensive

44%

Average

39%

Expensive

17%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Synmedic Laboratories
Address: No. 202, Sai Plaza, 187-188, Sant Nagar East Of Kailash,New Delhi 110065 India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Naltrex 50mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Naltrex Tablet

Benefits of Naltrex Tablet

Side effects of Naltrex Tablet

How to use Naltrex Tablet

How Naltrex Tablet works

All substitutes for Naltrex 50mg Tablet

Naltima 50 Tablet

Nodict 50mg Tablet

Naltrawave Tablet

Nalcovig 50 Tablet

Addline Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Buprenorphine (Injection Route)

Buprenorphine (Oral Route)

Buprenorphine (Transdermal Route)

Buprenorphine (Sublingual route)

Butorphanol (Injection Route)

Frequently asked questions

Can you take Naltrex 50mg Tablet forever?

Does Naltrex 50mg Tablet make you high/ sleepy?

Does Naltrex 50mg Tablet help with opiate cravings?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Opiates

References

User feedback

What are you using Naltrex Tablet for?

How much was the improvement?

What were the side-effects while using Naltrex 50mg Tablet?

How do you take Naltrex Tablet?

Please rate Naltrex 50mg Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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