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Nacphin 20mg Injection

Nalbuphine (20mg)
Genuine
Authenticity Assured
Prescription
required
Nacphin 20mg Injection is a pain-relieving medicine. It is used to treat moderate to severe pain. It is also used as a premedication before surgery. This medicine is generally used when alternative medicines are ineffective or inadequate.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 06 Apr 2026 | 03:49 PM (IST)
₹224 MRP ₹248.1210% off 
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General Information

Contains

Nalbuphine (20mg)

Marketer

Neon Laboratories Ltd

Storage

Store below 30°C
The content is shown in English
Nacphin 20mg Injection image
Nacphin 20mg Injection image

Product introduction

Nacphin 20mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.

The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), headache, dizziness, sleepiness, nausea, vomiting, sweating, and constipation. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Uses of Nacphin Injection

  • Moderate to severe pain

Benefits of Nacphin Injection

Moderate to severe pain
Nacphin 20mg Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Nacphin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Nacphin
  • Injection site reactions (pain, swelling, redness)
  • Headache
  • Dizziness
  • Sleepiness
  • Nausea
  • Vomiting
  • Sweating
  • Constipation

How to use Nacphin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Nacphin Injection works

Nacphin 20mg Injection is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.

Quick tips

  • Use Nacphin 20mg Injection as instructed by your doctor. Never take in greater amounts or more often than prescribed.
  • It causes sleepiness or drowsiness. If this happens to you, do not drive or use machinery.
  • Avoid consuming alcohol when taking the Nacphin 20mg Injection, as it may cause excessive sleepiness or drowsiness.
  • Inform your doctor if you have ever been diagnosed with kidney or liver problems.
  • Store opioid pain relievers in a safe place and out of reach of others.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Nacphin 20mg Injection may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Nacphin 20mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Nacphin 20mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Nacphin 20mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Nacphin 20mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Nacphin 20mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Nacphin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Naltrexone (Oral Route)

Do not consume Naltrexone with Nalbuphine; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Nalbuphine.
Severe

Alprazolam (Oral Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Alprazolam (Injection Route)

If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Chlordiazepoxide (Oral Route)

If concurrent use is essential, watch out for symptoms of Chlordiazepoxide side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Chlordiazepoxide as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe

Clobazam (Oral Route)

If concurrent use is essential, watch out for symptoms of Clobazam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Clobazam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.

Frequently asked questions

Nacphin 20mg Injection may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.

Fact Box

Chemical Class

Phenanthrene derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

Opioids

References

  1. Yaksh TL, WallaceIn MS. Opioids, Analgesia, and Pain Management. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 509.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 950-51.
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Neon Laboratories Ltd
Address: 140, Damji Samji Industrial Complex, Mahakali Caves Rd., Andheri(East), Mumbai-93.

Vendor Details

Country of origin: India

Lab tests offered by us

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