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Monopas Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 13 Mar 2026 | 01:39 PM (IST)
Monopas Tablet is an antibiotic medicine used to treat bacterial infections in your body. It is used to treat tuberculosis that is resistant to other medicines. It is generally used in combination with other medicines, as part of a regimen.
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General Information

Contains

Sodium aminosalicylate (1000mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 25°C
The content is shown in English
Monopas Tablet image
Monopas Tablet image
Monopas Tablet image
Monopas Tablet image
Monopas Tablet image
Monopas Tablet image

Product introduction

Monopas Tablet works by stopping the growth of the infection causing bacteria. It may be taken with or without food, preferably at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you to remember to take it. The dose will depend on what you are being treated for, but you should always complete a full course of this antibiotic as prescribed by your doctor. Do not stop taking it until you have finished, even when you feel better. If you stop taking it early, some bacteria may survive and the infection may come back.

The most common side effects of this medicine include allergic reactions, skin rash, vomiting, and nausea. Seek emergency medical help if you get a rash, itchy skin, swelling of face and mouth, or have difficulty breathing.

Before using it, you should tell your doctor if you are allergic to any antibiotics (especially sulpha medicines) or have any kidney or liver problems. Pregnant and breastfeeding mothers should not take this medicine. Your doctor may get regular blood and urine tests while undergoing treatment with this medicine.

Uses of Monopas Tablet

Benefits of Monopas Tablet

Tuberculosis (TB)
Monopas Tablet is used to treat tuberculosis, an infectious disease that mainly affects the lungs but can affect other parts of the body as well. It stops the growth of infection causing bacteria and helps in treating the infection. Take it in the dose and duration advised by the doctor. Your symptoms may improve before the infection is completely cured. Do not stop taking it without consulting your doctor as doing so may cause the infection to return or worsen. Follow your doctor’s instructions carefully to get maximum benefit.

Side effects of Monopas Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Monopas
  • Allergic reaction
  • Skin rash
  • Vomiting
  • Nausea

How to use Monopas Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Monopas Tablet may be taken with or without food.

How Monopas Tablet works

Monopas Tablet is an antibiotic. It stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication.

Quick tips

  • Monopas Tablet is used for the treatment of tuberculosis that is resistant to other drugs.
  • Do not skip any doses and finish the full course of treatment even if you feel better.
  • Take it with an acidic liquid such as fruit juices.
  • Diarrhea, nausea, and vomiting may occur as a side effect. Drink plenty of fluids and inform your doctor if you find blood in your stools.
  • Inform your doctor  if you have severe liver disease or if you are allergic to aspirin.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Monopas Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Monopas Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

UNSAFE
Monopas Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

SAFE
Monopas Tablet does not usually affect your ability to drive.
Kidney

Kidney

CAUTION
Monopas Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Monopas Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Monopas with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Methotrexate (Oral Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Methotrexate may raise blood levels of the active form of Sodium aminosalicylate.
Moderate

Acenocoumarol (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may monitor your treatment and adjust the doses as per the observations.
Moderate

Phenindione (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may monitor your treatment and adjust the doses as per the observations.
Moderate

Methotrexate (Injection Route)

Your doctor may monitor your treatment and adjust the doses as per the observations. Methotrexate may raise blood levels of the active form of Sodium aminosalicylate.
Moderate

Warfarin (Oral Route)

If concurrent use is essential, watch out for bleeding and consult your doctor immediately. They may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.
No, do not stop taking Monopas Tablet and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.
Yes, the use of Monopas Tablet can cause diarrhea. It is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If diarrhea gets severe, talk to your doctor about it.

Fact Box

Chemical Class

Aminosalicylic acids

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Sulphonamides

Related lab tests

Complete Blood Count

Erythrocyte Sedimentation Rate

Mycobacterium Tuberculosis DNA PCR - Qualitative

Peripheral Smear Examination

References

  1. Pugh DL, Jones ER, Martin WJ. Domiciliary treatment of pulmonary tuberculosis with sodium para-aminosalicylate. Lancet. 1950 Jul 15;2(6620):92-7. [Accessed 22 Dec. 2025]. Available from:
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User feedback

Thrice A Day
71%
Twice A Day
15%
Once A Day
12%
Four Times A Day
2%
Tuberculosis (TB)
82%
Bacterial infections
14%
Others
5%
Excellent
52%
Poor
33%
Average
15%
Diarrhea
29%
Allergic reaction
14%
No Side Effect
14%
Skin rash
14%
Vomiting
14%
With food
50%
With or without food
50%
Expensive
62%
Not Expensive
24%
Average
14%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

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