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Modalift 100mg Tablet

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 20 Feb 2026 | 03:03 PM (IST)
Modalift 100mg Tablet is a medicine used in the treatment of excessive daytime sleepiness (narcolepsy). It promotes wakefulness and helps you to stay awake. Thereby, reducing the tendency to fall asleep during the day and restoring the normal sleep cycle.
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General Information

Contains

Modafinil (100mg)

Marketer

Ryon Pharma

Storage

Store below 30°C
The content is shown in English
Modalift 100mg Tablet image
Modalift 100mg Tablet image

Product introduction

Modalift 100mg Tablet may also be used to treat obstructive sleep apnea and shift work sleep disorder. Additionally, it has cognitive-enhancing properties and can aid in increased focus, alertness, and productivity.


Modalift 100mg Tablet may be taken with or without food. It is advised to take this medicine at a fixed time each day to maintain a consistent level in the blood. If you miss any doses, take it as soon as you remember. Do not skip any doses and finish the full course of treatment even if you feel better. This medication mustn't be stopped suddenly as it may worsen your symptoms.


Some common side effects of this medicine include headache, nausea, nervousness, anxiety, and insomnia (difficulty sleeping). You may also have diarrhea, indigestion, back pain, and a runny nose. However, these side effects are temporary and usually resolve on their own in some time. Serious side effects are rare but may include skin rashes, severe mood changes, and signs of an allergic reaction. Consult your doctor immediately if you experience any of these side effects.


Always remember that this medicine is only used when advised by a doctor, as it is not a replacement for a good sleep routine. You should try to get the right amount of sleep every night. Before taking Modalift 100mg Tablet, inform your doctor if you have any problems with your kidneys, heart, liver, or have a history of seizures (epilepsy or fits). Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or if you have any suicidal thoughts.

Uses of Modalift Tablet

  • Treatment of Narcolepsy (Uncontrollable daytime sleepiness)

Benefits of Modalift Tablet

Treatment of Narcolepsy (Uncontrollable daytime sleepiness)
Narcolepsy is a sleep disorder that causes excessive daytime drowsiness. The affected person may experience excessive sleepiness, sleep paralysis, hallucinations, and, in some cases, episodes of cataplexy (partial or total loss of muscle control). Modalift 100mg Tablet stimulates the brain, keeping you fully awake and alert. It also relieves these abnormal symptoms and regulates the sleep cycle. This restores normal sleeping habits and improves your quality of life. You will feel more energetic and will be able to perform better in your daily activities. It is also reported to improve cognitive functions, such as enhanced memory, problem-solving abilities, and mental clarity.

Side effects of Modalift Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Modalift
  • Headache
  • Nausea
  • Nervousness
  • Anxiety
  • Dizziness
  • Indigestion
  • Back pain
  • Runny nose
  • Insomnia (difficulty in sleeping)
  • Diarrhea

How to use Modalift Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Modalift 100mg Tablet may be taken with or without food.

How Modalift Tablet works

Modalift 100mg Tablet modulates the levels of chemical messengers in the brain and exerts a stimulant effect to reduce extreme sleepiness.

Quick tips

  • Take it with or without food, preferably in the morning before you need to be alert.
  • It is not a replacement for a good sleep routine. Try to get the right amount of sleep every night.
  • Do not drive or do anything requiring concentration until you know how it affects you.
  • Avoid taking alcohol while taking this medicine, as it may increase the risk of side effects.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
  • It makes contraceptive pills less effective; consult with a doctor for effective contraception.
  • Talk to your doctor if you notice sudden mood changes or develop suicidal thoughts.
  • It may cause addiction/dependence potential when taken for the long term.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Modalift 100mg Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Modalift 100mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Modalift 100mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

UNSAFE
Modalift 100mg Tablet may cause side effects that could affect your ability to drive.
Patients with abnormal levels of sleepiness who take modafinil should be advised that their level of wakefulness may not return to normal, so they should avoid driving.
Kidney

Kidney

CAUTION
Modalift 100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Modalift 100mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Modalift with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Diazepam (Injection Route)

Watch out for symptoms of Modafinil side effects such as tremors, fever, sleepiness, dizziness, dry mouth or nausea and consult your doctor if you experience them. They may adjust or discontinue the doses if required. Modafinil may raise blood levels of Diazepam.
Severe

Diazepam (Oral Route)

Watch out for symptoms of Modafinil side effects such as tremors, fever, sleepiness, dizziness, dry mouth or nausea and consult your doctor if you experience them. They may adjust or discontinue the doses if required. Modafinil may raise blood levels of Diazepam.
Severe

Ulipristal acetate (Oral Route)

Do not consume Ulipristal acetate with Modafinil. If Ulipristal acetate is essential, ensure a gap of At least 4 weeks after discontinuing Modafinil. Please consult your doctor.
Severe

Sofosbuvir (Oral Route)

Do not consume Sofosbuvir with Modafinil. Modafinil may reduce blood levels of Sofosbuvir.
Severe

Lemborexant (Oral Route)

Do not consume Lemborexant with Modafinil. Modafinil may reduce blood levels of Lemborexant.

Frequently asked questions

No, rash can occur after day 1 to 2 months of starting the medicine. The period can be very variable and cannot be predicted. You should discontinue the use of Modalift 100mg Tablet and contact your doctor at the first sign of rash since it cannot be predicted whether the rash is serious or benign.
Modalift 100mg Tablet is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness). Modalift 100mg Tablet may help decrease your sleepiness, but it will not cure your sleep disorder. However, one of the common side effects of Modalift 100mg Tablet is trouble falling asleep, though it does not occur in everyone. Consult your doctor if you face any issues with sleep.
Yes, Modalift 100mg Tablet is more effective than amphetamine. It not only helps to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) but also improves task performance. On comparing, it shows less association with side effects such as excess locomotor activities, anxiety, jitteriness, or rebound effects, which are seen with amphetamine.
Modalift 100mg Tablet has a mood enhancing and mood-brightening effect. It has been tried in patients with depression.
Modalift 100mg Tablet should be taken strictly as advised by the doctor. It can be taken with or without food. Tablets should be swallowed whole with water.
Yes, Modalift 100mg Tablet may cause diarrhea. However, diarrhea and constipation both are equally common side effects associated with this medicine. Other common side effects related to gastrointestinal tract include abdominal pain, nausea, dry mouth, diarrhoea and indigestion.
Modalift 100mg Tablet not only has a waking effect (helps in reducing sleepiness) but is also known for its memory-enhancing effects. It has been used in patients with Alzheimer's disease, age-related memory decline and cognitive impairment in schizophrenia.
No, do not stop taking Modalift 100mg Tablet on your own without consulting your doctor. Sudden discontinuation of medicine may reduce the effect and with this your sleepiness may also return. Continue taking this medicine for the time recommended by your doctor, except when you experience serious side effects.
It is usually not recommended for long-term use. Studies have shown that long-term use of Modalift 100mg Tablet can damage the memory. It also has abuse potential. In addition, its prolonged use can induce stress response (especially if you are misusing and not getting good enough sleep and remaining wakeful for consecutive days). It can also affect your immunity which may make you prone to infection.
Modalift 100mg Tablet has abuse potential if used for longer periods. Usually, patients with a history of alcoholism and drug abuse are more likely to become addicted to Modalift 100mg Tablet. These patients should be carefully monitored and observed for signs of misuse or abuse (drug seeking behavior).
Modalift 100mg Tablet is a prescription medicine and should be taken only as prescribed by the doctor. It may cause serious side effects (e.g., a serious rash or a serious allergic reaction) that may affect your liver or blood cells. Seek immediate medical help on the occurrence of any such side effect as it can endanger life.
No, rash can occur after day 1 to 2 months of starting the medicine. The period can be very variable and cannot be predicted. You should discontinue the use of Modalift 100mg Tablet and contact your doctor at the first sign of rash since it cannot be predicted whether the rash is serious or benign.
Modalift 100mg Tablet is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness). Modalift 100mg Tablet may help decrease your sleepiness, but it will not cure your sleep disorder. However, one of the common side effects of Modalift 100mg Tablet is trouble falling asleep, though it does not occur in everyone. Consult your doctor if you face any issues with sleep.
Yes, Modalift 100mg Tablet is more effective than amphetamine. It not only helps to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) but also improves task performance. On comparing, it shows less association with side effects such as excess locomotor activities, anxiety, jitteriness, or rebound effects, which are seen with amphetamine.
Modalift 100mg Tablet has a mood enhancing and mood-brightening effect. It has been tried in patients with depression.
Modalift 100mg Tablet should be taken strictly as advised by the doctor. It can be taken with or without food. Tablets should be swallowed whole with water.
Yes, Modalift 100mg Tablet may cause diarrhea. However, diarrhea and constipation both are equally common side effects associated with this medicine. Other common side effects related to gastrointestinal tract include abdominal pain, nausea, dry mouth, diarrhoea and indigestion.
Modalift 100mg Tablet not only has a waking effect (helps in reducing sleepiness) but is also known for its memory-enhancing effects. It has been used in patients with Alzheimer's disease, age-related memory decline and cognitive impairment in schizophrenia.
No, do not stop taking Modalift 100mg Tablet on your own without consulting your doctor. Sudden discontinuation of medicine may reduce the effect and with this your sleepiness may also return. Continue taking this medicine for the time recommended by your doctor, except when you experience serious side effects.
It is usually not recommended for long-term use. Studies have shown that long-term use of Modalift 100mg Tablet can damage the memory. It also has abuse potential. In addition, its prolonged use can induce stress response (especially if you are misusing and not getting good enough sleep and remaining wakeful for consecutive days). It can also affect your immunity which may make you prone to infection.
Modalift 100mg Tablet has abuse potential if used for longer periods. Usually, patients with a history of alcoholism and drug abuse are more likely to become addicted to Modalift 100mg Tablet. These patients should be carefully monitored and observed for signs of misuse or abuse (drug seeking behavior).
Modalift 100mg Tablet is a prescription medicine and should be taken only as prescribed by the doctor. It may cause serious side effects (e.g., a serious rash or a serious allergic reaction) that may affect your liver or blood cells. Seek immediate medical help on the occurrence of any such side effect as it can endanger life.
No, rash can occur after day 1 to 2 months of starting the medicine. The period can be very variable and cannot be predicted. You should discontinue the use of Modalift 100mg Tablet and contact your doctor at the first sign of rash since it cannot be predicted whether the rash is serious or benign.
Modalift 100mg Tablet is used to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness). Modalift 100mg Tablet may help decrease your sleepiness, but it will not cure your sleep disorder. However, one of the common side effects of Modalift 100mg Tablet is trouble falling asleep, though it does not occur in everyone. Consult your doctor if you face any issues with sleep.
Yes, Modalift 100mg Tablet is more effective than amphetamine. It not only helps to treat excessive sleepiness caused by narcolepsy (a condition that causes excessive daytime sleepiness) but also improves task performance. On comparing, it shows less association with side effects such as excess locomotor activities, anxiety, jitteriness, or rebound effects, which are seen with amphetamine.
Modalift 100mg Tablet has a mood enhancing and mood-brightening effect. It has been tried in patients with depression.
Modalift 100mg Tablet should be taken strictly as advised by the doctor. It can be taken with or without food. Tablets should be swallowed whole with water.
Yes, Modalift 100mg Tablet may cause diarrhea. However, diarrhea and constipation both are equally common side effects associated with this medicine. Other common side effects related to gastrointestinal tract include abdominal pain, nausea, dry mouth, diarrhoea and indigestion.
Modalift 100mg Tablet not only has a waking effect (helps in reducing sleepiness) but is also known for its memory-enhancing effects. It has been used in patients with Alzheimer's disease, age-related memory decline and cognitive impairment in schizophrenia.
No, do not stop taking Modalift 100mg Tablet on your own without consulting your doctor. Sudden discontinuation of medicine may reduce the effect and with this your sleepiness may also return. Continue taking this medicine for the time recommended by your doctor, except when you experience serious side effects.
It is usually not recommended for long-term use. Studies have shown that long-term use of Modalift 100mg Tablet can damage the memory. It also has abuse potential. In addition, its prolonged use can induce stress response (especially if you are misusing and not getting good enough sleep and remaining wakeful for consecutive days). It can also affect your immunity which may make you prone to infection.
Modalift 100mg Tablet has abuse potential if used for longer periods. Usually, patients with a history of alcoholism and drug abuse are more likely to become addicted to Modalift 100mg Tablet. These patients should be carefully monitored and observed for signs of misuse or abuse (drug seeking behavior).
Modalift 100mg Tablet is a prescription medicine and should be taken only as prescribed by the doctor. It may cause serious side effects (e.g., a serious rash or a serious allergic reaction) that may affect your liver or blood cells. Seek immediate medical help on the occurrence of any such side effect as it can endanger life.

Fact Box

Chemical Class

Diphenylmethanes

Habit Forming

Yes

Therapeutic Class

NEURO CNS

Action Class

Eugeroic Agents

References

  1. Stahl SM, editor. Modafinil. In: Stahl's Essential Psychopharmacology: Prescriber's Guide. 5th ed. New York, New York: Cambridge University Press; 2014. pp. 453-56.
  2. Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 141, 145.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 933-34.
  4. Modafinil. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2012 [revised 06 Mar. 2017]. (online) Available from:
  5. Modafinil [Prescribing Information]. North Wales, PA: Teva Pharmaceuticals USA; 1998 [revised Jan. 2015]. [Accessed 25 Mar. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 25 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Ryon Pharma
Address: Village Ajnoud Ludhiana - 141421, Punjab, India

Vendor Details

Country of origin: India

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