Miprogen Vaginal gel

Progesterone (8% w/w)

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Miprogen Vaginal gel is used to restore menstrual cycles in women whose periods have stopped. It is a natural female hormone important for regulating ovulation (release of an egg from a woman's ovary) and menstruation. It is also used in the treatment of infertility to help you get pregnant.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 14 Apr 2026 | 01:19 PM (IST)

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Miprogen Vaginal gel

tube of 1.125 gm Vaginal gel

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C-Hop Vaginal gel

tube of 1.125 gm Vaginal gel

Progesterone (8% w/w)

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General Information

Contains

Progesterone (8% w/w)

Marketer

Bharat Serums & Vaccines Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

You should use Miprogen Vaginal gel as your doctor has advised. Do not use more or less than you have been advised and do not use it for longer than recommended. You may be asked to continue taking this medicine for a period after it is confirmed that you are pregnant.

The most common side effects include headache, feeling very tired, stomach cramps, pain or swelling in your abdomen and feeling sick. You may also feel bloated, less interested in sex and get pain or discharge in your vagina. Your doctor or nurse may be able to help you reduce or prevent side effects if they bother you or do not go away. Very occasionally people get a severe allergic reaction which needs urgent medical attention. Using this medicine may increase your risk of blood clots or breast cancer.

Miprogen Vaginal gel may not suit everybody, and you should tell your doctor if you have, or have had, breast cancer, unusual bleeding in the vagina or liver disease. You may be monitored more carefully if you have liver, kidney or heart problems or have diabetes or asthma. Let your doctor know your medical history to be safe. Check with your doctor about all other medicines which may affect, or be affected by, this medicine. You will probably have several tests both before and during treatment to check your womb. This medicine can alter your thinking or reactions and you may feel very tired so be careful if you drive or need to be alert. In general, alcohol is not recommended while taking this medicine.

Uses of Miprogen Vaginal gel

Benefits of Miprogen Vaginal gel

Female infertility
Miprogen Vaginal gel contains progesterone, a female hormone that is important in the regulation of ovulation and menstruation. It is used to cause menstrual periods in women who have not reached menopause but are not having periods due to a lack of natural progesterone in the body. Progesterone helps to prepare the uterus for pregnancy by causing the uterus lining (endometrium) to thicken. This increases the chance of a successful pregnancy. You should use the medicine as prescribed for it to be effective. You may be asked to continue with this treatment for a period after becoming pregnant.

Hormone replacement therapy
Hormone Placement Therapy (HRT) is a treatment to relieve symptoms of menopause such as hot flushes, night sweats, mood swings, vaginal dryness, and reduced sex drive. Since menopause can last for several years, this treatment can make a big improvement to your daily life and mood. Progesterone is one of two important hormones (the other is estrogen) used in this treatment. Vaginal tablets and gels are an easy way to deliver hormones but may not treat all the symptoms. You should use this medicine as it is prescribed, and for as long as it is prescribed by your doctor.

Side effects of Miprogen Vaginal gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Miprogen

Fatigue
Headache
Joint pain
Abnormal menstrual bleeding
Musculoskeletal (bone, muscle or joint) pain
Vertigo

How to use Miprogen Vaginal gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying

How Miprogen Vaginal gel works

Miprogen Vaginal gel contains a progesterone (a female sex hormone). It helps to establish and maintain pregnancy. It also prevents the increase in thickness of the endometrium (lining of the uterus) caused by estrogen.

All substitutes for Miprogen Vaginal gel

For information purposes only. Consult a doctor before taking any medicine.

C-Hop Vaginal gel

by Corona Remedies Pvt Ltd

₹212.81/vaginal gel

19% costlier

Quick tips

Miprogen Vaginal gel helps increase your chances of getting pregnant. It prepares the lining of your uterus to receive and nourish a fertilized egg.
If you become pregnant, it can be used for another 10 to 12 weeks until your progesterone levels are high enough.
It also helps regulate menstrual cycle in women who do not have a regular period due to a decrease in the hormone progesterone.
It exposes your body to less hormone invasion compared to pills or injections thereby preventing various gastric side effects.
Do not use tampons or other vaginal products for at least 6 hours before and after using Miprogen Vaginal gel.
You may get a brownish or white discharge during this time. It is not unusual, but talk to your doctor if it bothers you.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

The safety of Miprogen Vaginal gel during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

SAFE IF PRESCRIBED

Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Interaction with drugs

Taking Miprogen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Tamoxifen (Oral Route)

Avoid concurrent use. Please consult with your doctor.

Severe

Letrozole (Oral Route)

Avoid concurrent use. Please consult with your doctor.

Severe

Anastrozole (Oral Route)

Avoid concurrent use. Please consult with your doctor.

Severe

Pomalidomide (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Moderate

Ursodeoxycholic Acid (Oral Route)

Careful consideration is advised when taking Ursodeoxycholic Acid with Progesterone. Your doctor may monitor your treatment and adjust the doses as per the observations.

Frequently asked questions

What is Miprogen Vaginal gel and what is it used for?

Miprogen Vaginal gel is a synthetic form of micronized progesterone, which is a natural female sex hormone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. It is also prescribed along with estrogen as a part of hormonal replacement therapy to prevent endometrial hyperplasia (thickening of the lining of the uterus).

How and in what dose should I take Miprogen Vaginal gel?

Miprogen Vaginal gel should be taken strictly as advised by your doctor. The dose and duration will depend on your exact medical condition. It is recommended to use it at the same time each day to ensure consistent levels of medicine in your body.

Is Miprogen Vaginal gel safe?

Miprogen Vaginal gel is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.

What if I miss to take Miprogen Vaginal gel?

If you miss the dose, you should take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your usual dosing schedule. Do not take a double dose to make up for the missed one.

What are the common side effects which I can experience while taking Miprogen Vaginal gel?

The common side effects include vaginal discharge, headache, feeling tired, stomach cramps and breast tenderness. If any of the side effects bother you, please consult with your doctor.

Is Miprogen Vaginal gel effective?

Miprogen Vaginal gel is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Miprogen Vaginal gel too early, the symptoms may return or worsen.

Fact Box

Chemical Class

Gluco/mineralocorticoids, progestogin derivative

Habit Forming

Therapeutic Class

GYNAECOLOGICAL

Action Class

Natural Progesterone

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 706-707.
Levin ER, Hammes SR. Estrogens and Progestins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1180-85.
Progesteroene. Feltham, Middlesex: Merck; 2013 [revised Mar. 2015]. [Accessed 03 Apr. 2019] (online) Available from:
Progesterone. Poland Street, London: Besins Healthcare (UK) Ltd.; 2012 [revised 29 Jun. 2017]. [Accessed 03 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 03 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
Progesterone [Prescribing Information]. Pittsburgh, PA: Nutritional Specialties, Inc.; 2023. [Accessed 28 Mar. 2023] (online) Available from:
Draft Guidance on Progesterone, February 2022 [Accessed 28 Mar. 2023] (online) Available from:
Progesterone. Florham Park, NJ: Xiromed, LLC; 2026.

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Miprogen Vaginal gel

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Miprogen Vaginal gel

Benefits of Miprogen Vaginal gel

Side effects of Miprogen Vaginal gel

How to use Miprogen Vaginal gel

How Miprogen Vaginal gel works

All substitutes for Miprogen Vaginal gel

C-Hop Vaginal gel

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tamoxifen (Oral Route)

Letrozole (Oral Route)

Anastrozole (Oral Route)

Pomalidomide (Oral Route)

Ursodeoxycholic Acid (Oral Route)

Frequently asked questions

What is Miprogen Vaginal gel and what is it used for?

How and in what dose should I take Miprogen Vaginal gel?

Is Miprogen Vaginal gel safe?

What if I miss to take Miprogen Vaginal gel?

What are the common side effects which I can experience while taking Miprogen Vaginal gel?

Is Miprogen Vaginal gel effective?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Anti Mullerian Hormone

Glycosylated Hemoglobin

Testosterone Total

Thyroid Stimulating Hormone

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests